Protein Alignment Corin and Sfrp1

DIOPT Version :10

• Sequence 1: NP_610297.2
• Gene: Corin / 35691
• FlyBaseID: FBgn0033192
• Length: 1397
• Species: Drosophila melanogaster
• Sequence 2: NP_038862.2
• Gene: Sfrp1 / 20377
• MGIID: 892014
• Length: 314
• Species: Mus musculus
• Alignment Length: 325
• Identity: 71/325 - (21%)
• Similarity: 111/325 - (34%)
• Gaps: 90/325 - (27%)

  Fly   727 ILINAFALLAIAGGLAAY--------FNAYPTIKFVNKTIINTIHVEDTTSFGKNPAPGTC--LP 781
            :|..|.|||| ||..:.|        ..:|.:.:|..|                   |..|  :|
Mouse    18 LLALAAALLA-AGSASEYDYVSFQSDIGSYQSGRFYTK-------------------PPQCVDIP 62

  Fly   782 IIVRFCQGPQIPYNYTVFPNYIGHFGQLETQTDLDSYEALVDVRCYELVSLFLCTLFVPKCGQSG 846
            :.:|.|.  .:.|...|.||.:.|....|.:....|:..|::..|:....:|||:||.|.|  ..
Mouse    63 VDLRLCH--NVGYKKMVLPNLLEHETMAEVKQQASSWVPLLNKNCHMGTQVFLCSLFAPVC--LD 123

  Fly   847 ATVPPCKTLCTETMRRCGFFFDVFGLSLPEYLNCKLFKDFPSSEDCVGL-----DEVREVMRAAT 906
            ..:.||:.||......|......||...||.|.|   ..||..:.|:.:     .|..:......
Mouse   124 RPIYPCRWLCEAVRDSCEPVMQFFGFYWPEMLKC---DKFPEGDVCIAMTPPNTTEASKPQGTTV 185

  Fly   907 HPKCDGFQCDQNRCLPQ---EYVCDGHLDCMDQADEAKCERCGPDEIYCGDSQCIGTK------- 961
            .|.||      |....:   |::|........:..|.|.|.        ||.:.:..|
Mouse   186 CPPCD------NELKSEAIIEHLCASEFALRMKIKEVKKEN--------GDKKIVPKKKKPLKLG 236

  Fly   962 ------------HICDGIIDCPYGQDERNCLRLSERNGDVGTGVLEVYRIGQRQWMPACVKNWDR 1014
                        .:.:| .|||       |.:|.    ::....|.:.|..:.|::...:..||:
Mouse   237 PIKKKELKRLVLFLKNG-ADCP-------CHQLD----NLSHNFLIMGRKVKSQYLLTAIHKWDK 289

  Fly  1015  1014
            Mouse   290  289

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Corin	NP_610297.2	CRD_FZ	778..894	CDD:143549	34/117 (29%)
		LDLa	911..942	CDD:238060	5/33 (15%)
		LDLa	945..979	CDD:238060	7/52 (13%)
		SR	980..>1034	CDD:214555	6/35 (17%)
		Tryp_SPc	1104..1346	CDD:238113
Sfrp1	NP_038862.2	CRD_SFRP1	52..175	CDD:143552	36/148 (24%)
		NTR_Sfrp1_like	183..306	CDD:239635	23/133 (17%)