Protein Alignment Corin and Proc

DIOPT Version :10

• Sequence 1: NP_610297.2
• Gene: Corin / 35691
• FlyBaseID: FBgn0033192
• Length: 1397
• Species: Drosophila melanogaster
• Sequence 2: XP_006525784.1
• Gene: Proc / 19123
• MGIID: 97771
• Length: 484
• Species: Mus musculus
• Alignment Length: 516
• Identity: 135/516 - (26%)
• Similarity: 199/516 - (38%)
• Gaps: 161/516 - (31%)

  Fly   890 EDCVGLDEVREVMRAATHPKC------DGFQCDQNRCLPQEYVCDGHLDCMDQADEAKCERCGPD 948
            |:....:|.:|:.:.......      ||.||.   ..|.::.||           :.|
Mouse    84 EEICDFEEAQEIFQNVEDTLAFWIKYFDGDQCS---APPLDHQCD-----------SPC------ 128

  Fly   949 EIYCGDSQCIGTKHICDGI----IDCPYGQDERNC---LRLSE---RNGDVGTGVLEVYRIGQRQ 1003
               ||...||      |||    ..|..|.:.:.|   ||..:   .||......||... |:|
Mouse   129 ---CGHGTCI------DGIGSFSCSCDKGWEGKFCQQELRFQDCRVNNGGCLHYCLEESN-GRR- 182

  Fly  1004 WMPACVKNWDRAVSPSAVCSILGYSAVNATSVLTQLTHRPLLATVNVSTDIWKMYAKRKSTLMQE 1068
                |      |.:|       ||.                                    |..:
Mouse   183 ----C------ACAP-------GYE------------------------------------LADD 194

  Fly  1069 FANCKKTEDYPMADLTCSNYECGRVKRGRHK----------------PSRRIIGGTQASPGNWPF 1117
            ...||.|.::|          ||::.|...|                |..||:.||....|:.|:
Mouse   195 HMRCKSTVNFP----------CGKLGRWIEKKRKILKRDTDLEDELEPDPRIVNGTLTKQGDSPW 249

  Fly  1118 LAAILGGPEKIFYCAGVLISDQWVLTASHCV----------GNYSVIDLEDWTIQLGVTRRNSFT 1172
            .|.:|...:|: .|.||||...|||||:|||          |.|.:...:.|.:.|
Mouse   250 QAILLDSKKKL-ACGGVLIHTSWVLTAAHCVEGTKKLTVRLGEYDLRRRDHWELDL--------- 304

  Fly  1173 YSGQKVKVKAVIPHPQYNMAIAHDNDIALFQLATRVAFHEHLLPVCLPPPSVRN--LHPGTLCTV 1235
                  .:|.::.||.|..: :.||||||.:||......:.::|:|||...:..  ...|....|
Mouse   305 ------DIKEILVHPNYTRS-SSDNDIALLRLAQPATLSKTIVPICLPNNGLAQELTQAGQETVV 362

  Fly  1236 IGWGKRED--KDPKSTYEYIVNEVQVPIITRNQCDEWLDNLTVSEGMVCAGFDDGGKDACQGDSG 1298
            .|||.:.|  ||.:....:|:..:::|::.||:|.|.:.|: |||.|:|||.....:|||.||||
Mouse   363 TGWGYQSDRIKDGRRNRTFILTFIRIPLVARNECVEVMKNV-VSENMLCAGIIGDTRDACDGDSG 426

  Fly  1299 GPLLCPYPGEKNRWFVGGIVSWGIMCAHPRLPGVYANVVQYVPWIQEQIAKHSRPIKEDRV 1359
            ||::..:.|   .||:.|:||||..|.|....|:|..|..|:.||...|.:....:|..::
Mouse   427 GPMVVFFRG---TWFLVGLVSWGEGCGHTNNYGIYTKVGSYLKWIHSYIGEKGVSLKSQKL 484

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Corin	NP_610297.2	CRD_FZ	778..894	CDD:143549	1/3 (33%)
		LDLa	911..942	CDD:238060	7/30 (23%)
		LDLa	945..979	CDD:238060	9/37 (24%)
		SR	980..>1034	CDD:214555	13/56 (23%)
		Tryp_SPc	1104..1346	CDD:238113	88/255 (35%)
Proc	XP_006525784.1	GLA	50..110	CDD:214503	3/25 (12%)
		EGF_CA	111..155	CDD:238011	17/72 (24%)
		FXa_inhibition	163..198	CDD:464251	12/89 (13%)
		Tryp_SPc	236..470	CDD:238113	88/254 (35%)