Protein Alignment Corin and Klk1b5

DIOPT Version :10

• Sequence 1: NP_610297.2
• Gene: Corin / 35691
• FlyBaseID: FBgn0033192
• Length: 1397
• Species: Drosophila melanogaster
• Sequence 2: NP_032482.1
• Gene: Klk1b5 / 16622
• MGIID: 892020
• Length: 261
• Species: Mus musculus
• Alignment Length: 285
• Identity: 85/285 - (29%)
• Similarity: 129/285 - (45%)
• Gaps: 73/285 - (25%)

  Fly  1105 IGGTQASPGNWPFLAAILGG--------PEKI-------FYCAGVLISDQWVLTASHCVGNYSVI 1154
            :||..|:|   |..:.|.||        |.::       :.|.|||::..|||||:||..
Mouse    12 LGGIDAAP---PVQSRIFGGFNCEKNSQPWQVAVYRFTKYQCGGVLLNANWVLTAAHCHN----- 68

  Fly  1155 DLEDWTIQLGVTRRNSF---TYSGQKVKVKAVIPHPQYNMAIAHD----------NDIALFQLAT 1206
              :.:.:.||   :|:|   ..|.|...|...||||.:||::.::          ||:.|.:|..
Mouse    69 --DKYQVWLG---KNNFFEDEPSAQHRLVSKAIPHPDFNMSLLNEHTPQPEDDYSNDLMLLRLKK 128

  Fly  1207 RVAFHEHLLPVCLP--PPSVRNLHPGTLCTVIGWGK-----REDKDPKS--TYEYIVNEVQVPII 1262
            .....:.:.|:.||  .|.:     |:.|...|||.     .|..|...  .::.:.||..|...
Mouse   129 PADITDVVKPIDLPTEEPKL-----GSTCLASGWGSITPVIYEPADDLQCVNFKLLPNEDCVKAH 188

  Fly  1263 TRNQCDEWLDNLTVSEGMVCAGFDDGGKDACQGDSGGPLLCPYPGEKNRWFVGGIVSWG-IMCAH 1326
            ...          |::.|:|||..|||||.|.|||||||:|.       ..:.||.||| ..|..
Mouse   189 IEK----------VTDVMLCAGDMDGGKDTCMGDSGGPLICD-------GVLHGITSWGPSPCGK 236

  Fly  1327 PRLPGVYANVVQYVPWIQEQIAKHS 1351
            |.:||:|..::::..||::.|||::
Mouse   237 PNVPGIYTKLIKFNSWIKDTIAKNA 261

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Corin	NP_610297.2	CRD_FZ	778..894	CDD:143549
		LDLa	911..942	CDD:238060
		LDLa	945..979	CDD:238060
		SR	980..>1034	CDD:214555
		Tryp_SPc	1104..1346	CDD:238113	82/278 (29%)
Klk1b5	NP_032482.1	Tryp_SPc	24..253	CDD:214473	75/260 (29%)