Protein Alignment Corin and Klk1

DIOPT Version :10

• Sequence 1: NP_610297.2
• Gene: Corin / 35691
• FlyBaseID: FBgn0033192
• Length: 1397
• Species: Drosophila melanogaster
• Sequence 2: NP_034769.4
• Gene: Klk1 / 16612
• MGIID: 102850
• Length: 261
• Species: Mus musculus
• Alignment Length: 281
• Identity: 85/281 - (30%)
• Similarity: 134/281 - (47%)
• Gaps: 67/281 - (23%)

  Fly  1105 IGGTQASPGNWPFLAAILGG--------PEKI-------FYCAGVLISDQWVLTASHCVGNYSVI 1154
            :||..|:|   |..:.|:||        |.::       :.|.|:|::..|||||:||..
Mouse    12 LGGIDAAP---PVQSRIVGGFNCEKNSQPWQVAVYRFTKYQCGGILLNANWVLTAAHCHN----- 68

  Fly  1155 DLEDWTIQLGVTRRNSFTY---SGQKVKVKAVIPHPQYNMAIAHD----------NDIALFQLAT 1206
              :.:.:.||   :|:|..   |.|...|...||||.:||::.::          ||:.|.:|..
Mouse    69 --DKYQVWLG---KNNFLEDEPSAQHRLVSKAIPHPDFNMSLLNEHTPQPEDDYSNDLMLLRLKK 128

  Fly  1207 RVAFHEHLLPVCLP--PPSVRNLHPGTLCTVIGWGKREDKDPKSTYEYIVNEVQ---VPIITRNQ 1266
            .....:.:.|:.||  .|.:     |:.|...|||    ......||| .:|:|   :.::....
Mouse   129 PADITDVVKPIDLPTEEPKL-----GSTCLASGWG----SITPVKYEY-PDELQCVNLKLLPNED 183

  Fly  1267 CDE-WLDNLTVSEGMVCAGFDDGGKDACQGDSGGPLLCPYPGEKNRWFVGGIVSWG-IMCAHPRL 1329
            |.: .::.:|  :.|:|||..|||||.|.|||||||:|.       ..:.||.||| ..|..|.:
Mouse   184 CAKAHIEKVT--DDMLCAGDMDGGKDTCAGDSGGPLICD-------GVLQGITSWGPSPCGKPNV 239

  Fly  1330 PGVYANVVQYVPWIQEQIAKH 1350
            ||:|..|:.:..||:|.:|::
Mouse   240 PGIYTRVLNFNTWIRETMAEN 260

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Corin	NP_610297.2	CRD_FZ	778..894	CDD:143549
		LDLa	911..942	CDD:238060
		LDLa	945..979	CDD:238060
		SR	980..>1034	CDD:214555
		Tryp_SPc	1104..1346	CDD:238113	83/275 (30%)
Klk1	NP_034769.4	Tryp_SPc	24..253	CDD:214473	76/257 (30%)