| Sequence 1: | NP_610297.2 | Gene: | Corin / 35691 | FlyBaseID: | FBgn0033192 | Length: | 1397 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_032081.3 | Gene: | Fzd4 / 14366 | MGIID: | 108520 | Length: | 537 | Species: | Mus musculus |
| Alignment Length: | 191 | Identity: | 53/191 - (27%) |
|---|---|---|---|
| Similarity: | 80/191 - (41%) | Gaps: | 26/191 - (13%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 767 TTSFGKNPAPGTCLPIIVRFCQGPQIPYNYTVFPNYIGHFGQLETQTDLDSYEALVDVRCYELVS 831
Fly 832 LFLCTLFVPKCGQS-GATVPPCKTLCTETMRRCGFFFDVFGLSLPEYLNCKLFKDFPSSED---- 891
Fly 892 CV---GLDEVREVMRAATHPKCDGFQCDQNRCLPQEYV-CDGHLDCMDQADEAKCERCGPD 948 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Corin | NP_610297.2 | CRD_FZ | 778..894 | CDD:143549 | 38/123 (31%) |
| LDLa | 911..942 | CDD:238060 | 5/31 (16%) | ||
| LDLa | 945..979 | CDD:238060 | 3/4 (75%) | ||
| SR | 980..>1034 | CDD:214555 | |||
| Tryp_SPc | 1104..1346 | CDD:238113 | |||
| Fzd4 | NP_032081.3 | CRD_FZ4 | 42..167 | CDD:143557 | 39/129 (30%) |
| 7tmF_FZD4 | 209..509 | CDD:320166 | |||
| TM helix 1 | 218..243 | CDD:320166 | |||
| TM helix 2 | 252..273 | CDD:320166 | |||
| TM helix 3 | 303..329 | CDD:320166 | |||
| TM helix 4 | 346..362 | CDD:320166 | |||
| TM helix 5 | 384..413 | CDD:320166 | |||
| TM helix 6 | 433..460 | CDD:320166 | |||
| TM helix 7 | 470..495 | CDD:320166 | |||
| Lys-Thr-X-X-X-Trp motif, mediates interaction with the PDZ domain of Dvl family members. /evidence=ECO:0000250 | 499..504 | ||||
| PDZ-binding | 535..537 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||