Protein Alignment Corin and fz4

DIOPT Version :10

• Sequence 1: NP_610297.2
• Gene: Corin / 35691
• FlyBaseID: FBgn0033192
• Length: 1397
• Species: Drosophila melanogaster
• Sequence 2: XP_319612.2
• Gene: fz4 / 1279837
• VectorBaseID: AGAMI1_009142
• Length: 616
• Species: Anopheles gambiae
• Alignment Length: 533
• Identity: 120/533 - (22%)
• Similarity: 183/533 - (34%)
• Gaps: 179/533 - (33%)

  Fly   778 TCLPIIVRFCQGPQIPYNYTVFPNYIGHFGQLETQTDLDSYEALVDVRCYELVSLFLCTLFVPKC 842
            ||.||.:..|:|  |.||.|..||.:||..|.:....|.::..|:...|.:.:..|||..:||.|
Mosquito    33 TCEPIRIELCRG--IGYNETSLPNIVGHELQSDANFTLQTFFPLIQFGCSKQLKFFLCATYVPMC 95

  Fly   843 -GQSGATVPPCKTLCTETMRRCGFFFDVFGLSLPEYLNCKLFKDFPSSED-CV---GLDEVREVM 902
             .:....:.||::||.....||......||...|..|:|..|.:..:.|. |:   |.....||:
Mosquito    96 TPKVSMPIGPCRSLCNTVKNRCHPILQGFGFPWPSALDCNRFPEENNHEHMCMQGPGEPAEGEVL 160

  Fly   903 RAATHPKCDGFQ-----CDQNRCLPQEYVCDGHLDCMDQADEAKCERCGPDEIYCGDSQCIGTKH 962
             .:..|.|.|.|     ...||                      ..||.|
Mosquito   161 -VSDRPSCQGLQRSNLYVQLNR----------------------SGRCAP--------------- 187

  Fly   963 ICDGIIDCPYGQDERNCLRL---SERNGDVGTGVLEVYRIGQRQWMPACV----KNWDRAVSPSA 1020
            :|:.  |..:.|:|::...:   |.....:||.::..          .|:    |.||:::.|..
Mosquito   188 LCEA--DIMFEQNEKHFAEVWLTSWSVAALGTAIVAT----------LCLILSTKRWDKSLMPLV 240

  Fly  1021 V--CSILGYSAV------NATS------------VLTQ-LTHRPLLAT------VNVSTDIWKMY 1058
            :  |.:....||      |||:            :||. |:..|..||      ..:|..:|  :
Mosquito   241 ISHCLVTVGWAVRWLAGRNATACGYDPQLPGVALLLTDGLSTAPCAATFLLRYYFGLSAAVW--W 303

  Fly  1059 AKRKSTLMQEFANCKKTEDYPMADLTCSNYECGRVKRGRHKPSRRIIGGTQASPGNWP------- 1116
            |                       :.|..:.         |..||::|....||.:..
Mosquito   304 A-----------------------ILCLRWS---------KSVRRLLGTDLTSPADLHAEKPNSS 336

  Fly  1117 ----FLAAILGGP---EKIFYCAGVLISDQWVLTASHCVGNYS---------VIDLEDWTIQLGV 1165
                |..|..|.|   ..|...|.::.:|:  |..|..:||.|         |..|..|.|..|.
Mosquito   337 HDTLFQLAAWGIPAVLTVIVLVARLVDADE--LFGSCFIGNQSDKALLTFVIVPLLSSWVIGSGY 399

  Fly  1166 TRRNSFTYSGQKVKVKAVIPHPQYNMAI-AHDNDIALFQLATRVA------FHEHLLPVC----- 1218
            .    ||   ..::.::..|...:|:.: .|.....||..|...|      |:|:   .|
Mosquito   400 L----FT---AYLRKRSAAPPLVHNLPVHIHGMGKFLFIYAVPSAALLMLMFYEY---ACRENWL 454

  Fly  1219 -LPPPSVRN-LHP 1229
             ||.||:.: |||
Mosquito   455 HLPHPSLDSPLHP 467

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Corin	NP_610297.2	CRD_FZ	778..894	CDD:143549	38/120 (32%)
		LDLa	911..942	CDD:238060	4/35 (11%)
		LDLa	945..979	CDD:238060	6/33 (18%)
		SR	980..>1034	CDD:214555	13/68 (19%)
		Tryp_SPc	1104..1346	CDD:238113	39/163 (24%)
fz4	XP_319612.2	None