Protein Alignment Corin and sfrp5

DIOPT Version :10

• Sequence 1: NP_610297.2
• Gene: Corin / 35691
• FlyBaseID: FBgn0033192
• Length: 1397
• Species: Drosophila melanogaster
• Sequence 2: NP_571933.1
• Gene: sfrp5 / 117510
• ZFINID: ZDB-GENE-011108-2
• Length: 310
• Species: Danio rerio
• Alignment Length: 274
• Identity: 62/274 - (22%)
• Similarity: 100/274 - (36%)
• Gaps: 63/274 - (22%)

  Fly   770 FGKNPAPGTC--LPIIVRFCQGPQIPYNYTVFPNYIGHFGQLETQTDLDSYEALVDVRCYELVSL 832
            :.|.|   .|  :|..:|.|.  .:.|.....||.:.|....|.:....|:..|:..||:....:
Zfish    46 YAKQP---QCVDIPADLRLCY--NVGYKKMRLPNLLDHETMPEVKQQAGSWVPLLAKRCHADTQV 105

  Fly   833 FLCTLFVPKCGQSGATVPPCKTLCTETMRRCGFFFDVFGLSLPEYLNCKLFKDFPSSED-CVGLD 896
            |||:||.|.|  ....:.||::||......|....:.:|...||.|.|   :.||...| |:.:.
Zfish   106 FLCSLFAPVC--LDRPIYPCRSLCEAVRDSCAPVMETYGFPWPEMLQC---EKFPIDNDLCIPMQ 165

  Fly   897 ----EVREVMRAATHPKCDG-FQCDQNRCLPQEYVCDGHLDCMDQADEAKCERCGPDEIYCGDSQ 956
                ...:...:...|.||. .:.|    ...|:.|........:..|||.|:        ||.:
Zfish   166 FSAGHATQTPVSKVCPPCDNELKAD----TIMEHYCASDFALKMKIKEAKKEK--------GDRK 218

  Fly   957 CIG---------------------TKHICDGIIDCPYGQDERNCLRLSERNGDVGTGVLEVYRIG 1000
            .|.                     |.:|.:| .:||       |.:|.    ::|:..|.:.|..
Zfish   219 LIAAQKKKKVLKMGILRKKDLKKLTLYIKNG-ANCP-------CSQLD----NLGSNFLIMGRKV 271

  Fly  1001 QRQWMPACVKNWDR 1014
            .:|.:...:..||:
Zfish   272 DQQLLLMSIHKWDK 285

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Corin	NP_610297.2	CRD_FZ	778..894	CDD:143549	34/118 (29%)
		LDLa	911..942	CDD:238060	6/31 (19%)
		LDLa	945..979	CDD:238060	8/54 (15%)
		SR	980..>1034	CDD:214555	7/35 (20%)
		Tryp_SPc	1104..1346	CDD:238113
sfrp5	NP_571933.1	CRD_SFRP5	46..172	CDD:143553	36/135 (27%)
		NTR_Sfrp1_like	177..302	CDD:239635	26/133 (20%)