Protein Alignment Corin and KLK11

DIOPT Version :10

• Sequence 1: NP_610297.2
• Gene: Corin / 35691
• FlyBaseID: FBgn0033192
• Length: 1397
• Species: Drosophila melanogaster
• Sequence 2: XP_011524671.1
• Gene: KLK11 / 11012
• HGNCID: 6359
• Length: 307
• Species: Homo sapiens
• Alignment Length: 267
• Identity: 89/267 - (33%)
• Similarity: 127/267 - (47%)
• Gaps: 41/267 - (15%)

  Fly  1103 RIIGGTQASPGNWPFLAAILGGPEKI-FYCAGVLISDQWVLTASHCV------------------ 1148
            |||.|.:..|.:.|:.||:.   ||. ..|...||:.:|:|||:||:
Human    53 RIIKGFECKPHSQPWQAALF---EKTRLLCGATLIAPRWLLTAAHCLKPWVSLTSPTHVSPDLSS 114

  Fly  1149 GNYSVIDLEDWTIQLGVTRRNSFTYSGQKVKVKAVIPHPQYNMAIA---HDNDIALFQLATRVAF 1210
            .||.:..|..:.:.||...........|........|||.:|.::.   |.|||.|.::|:.|:.
Human   115 SNYCLSHLSRYIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNSLPNKDHRNDIMLVKMASPVSI 179

  Fly  1211 HEHLLPVCLPPPSVRNLHPGTLCTVIGWGKREDKDPKSTYEYIVNEVQVPIITRNQCDE-WLDNL 1274
            ...:.|:.|   |.|.:..||.|.:.|||  ....|:....:.:....:.||...:|:. :..|:
Human   180 TWAVRPLTL---SSRCVTAGTSCLISGWG--STSSPQLRLPHTLRCANITIIEHQKCENAYPGNI 239

  Fly  1275 TVSEGMVCAGFDDGGKDACQGDSGGPLLCPYPGEKNRWFVGGIVSWG-IMCAHPRLPGVYANVVQ 1338
            |  :.||||...:||||:|||||||||:|       ...:.||:||| ..||..|.||||..|.:
Human   240 T--DTMVCASVQEGGKDSCQGDSGGPLVC-------NQSLQGIISWGQDPCAITRKPGVYTKVCK 295

  Fly  1339 YVPWIQE 1345
            ||.||||
Human   296 YVDWIQE 302

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Corin	NP_610297.2	CRD_FZ	778..894	CDD:143549
		LDLa	911..942	CDD:238060
		LDLa	945..979	CDD:238060
		SR	980..>1034	CDD:214555
		Tryp_SPc	1104..1346	CDD:238113	88/266 (33%)
KLK11	XP_011524671.1	Tryp_SPc	53..300	CDD:214473	85/263 (32%)