Protein Alignment Corin and LOC100495541

DIOPT Version :10

• Sequence 1: NP_610297.2
• Gene: Corin / 35691
• FlyBaseID: FBgn0033192
• Length: 1397
• Species: Drosophila melanogaster
• Sequence 2: XP_031749237.1
• Gene: LOC100495541 / 100495541
• XenbaseID: XB-GENE-29082731
• Length: 659
• Species: Xenopus tropicalis
• Alignment Length: 674
• Identity: 167/674 - (24%)
• Similarity: 256/674 - (37%)
• Gaps: 165/674 - (24%)

  Fly   737 IAGGLAAYFNAYP---TIKFVNKTIINTIHVEDTTSFGKN--PAPGTCLPIIVRFCQGPQIPYNY 796
            |.||.||...|:|   ::::      ..||:...:..|.:  .....|..|       .|.|.::
 Frog    44 IVGGSAATEGAWPWQVSLRY------KGIHICGGSVIGTHWILTAAHCFLI-------SQSPSDF 95

  Fly   797 TV----------FPNYIGH-FGQLETQTDLDSYEALVDVRCYELVSLFLCTLFV-PKCGQSGATV 849
            .|          .||.|.: ..::...:..||.....|:......|....|.:: |.|..|.:..
 Frog    96 EVRLGAYQLSLTSPNEITYKVDRIIVNSQFDSSSHYGDIALIRPTSPITYTPYILPVCLPSTSNS 160

  Fly   850 PPCKTLCTETMRRCGFFFDVFGLSLPEYLNCKLFKDFPSSEDCVGLDEVREVMRAATHPKCDGFQ 914
            .|....|..|    |:....|.::||          :|.:        :::||.    |......
 Frog   161 FPEGMECWVT----GWGTTAFQVNLP----------YPQT--------LQQVMT----PLISRTS 199

  Fly   915 CDQ-----------NRCLPQEYVCDGHLDCMDQADEAKCERCGPDEIYCGDSQCIGTKHIC--DG 966
            |||           ...:|.:.:|.|:  ...|.|  .|:         |||   |...:|  .|
 Frog   200 CDQMYHIGTNVPSSTAIIPSDQICAGY--AAGQKD--SCQ---------GDS---GGPLVCKLQG 248

  Fly   967 IIDCPYGQDERNCLRLSERNGDVGTGVLEVYRIGQRQWMPACVKNWDRAVSPSAVCSILGY---- 1027
            |                            .|:||...|...|.    .|..|.....:..|
 Frog   249 I----------------------------WYQIGFVTWGDGCA----IANRPGVYTLVPAYQSWL 281

  Fly  1028 SAVNATSVLTQLTHRPLLATVNVSTDIWKMYAKRKSTLMQE---------FANCKKTEDYPMADL 1083
            |:.|||.....:...|..|...:.:::..:::..||..:..         .|..|.:...|....
 Frog   282 SSYNATENTVNVDSVPTTAPPTLISNVSSLFSLSKSAPLPGACSLLCIWLIAMAKDSSVSPSVSD 346

  Fly  1084 TCSNYECGRVKRGRHKP--SRRIIGGTQASPGNWPFLAAILGGPEKIFYCAGVLISDQWVLTASH 1146
            |.|...||       .|  |.||:|||.|:.|.||:..::......|  |.|.||:.||::||:|
 Frog   347 TTSTLSCG-------SPLVSNRIVGGTDATDGAWPWQVSLDYHGSHI--CGGSLIATQWIMTAAH 402

  Fly  1147 CVGNYSVIDLEDWTIQLGVTRRNSFTYSGQKVKVKAVIPHPQYNMAIAHDNDIALFQLATRVAFH 1211
            |. .||. ...|:.|:||..:.:..:.......|.::|.:...:.:.  :.||||.:|.:.:.:.
 Frog   403 CF-EYSK-SPSDYKIRLGAYQLSLISPHEITSTVDSIIVNSPNSSST--NTDIALIRLTSPITYT 463

  Fly  1212 EHLLPVCLPPPSVRNLHPGTLCTVIGWGKREDKDPKSTYEYIVNEVQVPIITRNQCDEW-----L 1271
            :::||:|||..| .....|..|.|.|||....: ....|...:.:|..|:|:|..|::.     |
 Frog   464 KYILPICLPSTS-DGFTEGMECWVTGWGTIASQ-VNLPYPMTLQQVMTPLISRATCNQMYNTDSL 526

  Fly  1272 DNLTVSEGMVCAGFDDGGKDACQGDSGGPLLCPYPGEKNRWFVGGIVSWGIMCAHPRLPGVYANV 1336
            .::.|....:|||:..|.||:|||||||||:|...|   .|:..||||||..||....||||..|
 Frog   527 LSVVVPLDQICAGYAAGQKDSCQGDSGGPLVCQLQG---IWYQIGIVSWGEGCAVRNRPGVYTLV 588

  Fly  1337 VQYVPWIQEQIAKHSRPIKEDRVN 1360
            ..|..|:          |.|:..|
 Frog   589 PAYYSWV----------IAEENTN 602

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Corin	NP_610297.2	CRD_FZ	778..894	CDD:143549	24/127 (19%)
		LDLa	911..942	CDD:238060	8/41 (20%)
		LDLa	945..979	CDD:238060	7/35 (20%)
		SR	980..>1034	CDD:214555	11/57 (19%)
		Tryp_SPc	1104..1346	CDD:238113	85/246 (35%)
LOC100495541	XP_031749237.1	Tryp_SPc	44..283	CDD:238113	61/325 (19%)
		Tryp_SPc	362..595	CDD:238113	84/243 (35%)