DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Corin and fzd9

DIOPT Version :9

Sequence 1:	NP_610297.2	Gene:	Corin / 35691	FlyBaseID:	FBgn0033192	Length:	1397	Species:	Drosophila melanogaster
Sequence 2:	XP_004911821.1	Gene:	fzd9 / 100487936	XenbaseID:	XB-GENE-478317	Length:	587	Species:	Xenopus tropicalis

Alignment Length:	171	Identity:	51/171 - (29%)
Similarity:	72/171 - (42%)	Gaps:	27/171 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   722 FRLFQILINAFALLAIAGGLAAYFNAYPTIKFVNKTIINTIHVEDTTSFGKNPAPGTCLPIIVRF 786
            |||..:..:||....:|..||.....|...:                  |:.   ..|.||.:..
Frog     2 FRLSSLFTSAFVWQLLAVTLALEMGLYDVER------------------GRE---AKCEPIQIPM 45

  Fly   787 CQGPQIPYNYTVFPNYIGHFGQLETQTDLDSYEALVDVRCYELVSLFLCTLFVPKCGQSGAT-VP 850
            |||  |.||.|..|||:||..|.|....|..:..||:..|:..:..|||:|:.|.|.:..:| :|
Frog    46 CQG--IGYNMTRMPNYVGHESQEEAAAKLQEFAPLVEYGCHIHLRFFLCSLYAPMCTEQVSTSIP 108

  Fly   851 PCKTLCTETMRRCGFFFDVFGLSLPEYLNCKLFKDFPSSED 891
            .||.:|....::|....:.|....||.|:|   ...||..|
Frog   109 ACKPMCEAARQKCAPIMESFQYVWPESLDC---DRLPSKND 146

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Corin	NP_610297.2	CRD_FZ	778..894	CDD:143549	41/115 (36%)
		LDLa	911..942	CDD:238060
		LDLa	945..979	CDD:238060
		SR	980..>1034	CDD:214555
		SRCR	992..1086	CDD:278931
		Tryp_SPc	1103..1343	CDD:214473
		Tryp_SPc	1104..1346	CDD:238113
fzd9	XP_004911821.1	CRD_FZ	34..159	CDD:382974	41/121 (34%)
		7tmF_FZD9	216..535	CDD:320164
		TM helix 1	225..250	CDD:320164
		TM helix 2	259..280	CDD:320164
		TM helix 3	309..335	CDD:320164
		TM helix 4	352..368	CDD:320164
		TM helix 5	390..420	CDD:320164
		TM helix 6	439..466	CDD:320164
		TM helix 7	496..521	CDD:320164
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910