Protein Alignment Corin and tmprss15

DIOPT Version :10

• Sequence 1: NP_610297.2
• Gene: Corin / 35691
• FlyBaseID: FBgn0033192
• Length: 1397
• Species: Drosophila melanogaster
• Sequence 2: XP_068072228.2
• Gene: tmprss15 / 100148042
• ZFINID: ZDB-GENE-091204-83
• Length: 1025
• Species: Danio rerio
• Alignment Length: 1235
• Identity: 269/1235 - (21%)
• Similarity: 417/1235 - (33%)
• Gaps: 397/1235 - (32%)

  Fly   240 DADGISDDDRMSLEN-SVFDESL---TSTPVKVAGYLAGRYAGLSHMAKRAQRSSSSTVDSAY-G 299
            |..|.....::.:.| :||.|.|   .|...|...|                 .:...:..|| .
Zfish    48 DETGSEFTGKLVISNGTVFTEELLNKNSAQFKALAY-----------------DTEQRISDAYRR 95

  Fly   300 SSLGGHSERFASS--------STSVDFRSRFSSVDTQSSLDEKPLSSSIDSPLARDPRDAYRERA 356
            |||   .|:|.||        |..|||...|..|              :||.:|:..
Zfish    96 SSL---KEQFRSSKVNEFSEGSVVVDFDVFFRGV--------------LDSEMAQKQ-------- 135

  Fly   357 VLNDAMHKLNNNNTSLGLALYSASNNNNGSSVASDGSQLPVVPARKQPPPVKGSSNSSNSIGETQ 421
             |.|.:.:..:.|..|.:.:.|....:..::.....:..||    ..|...|..::....|.:|.
Zfish   136 -LVDGLQQGESGNDGLVIDIGSVEVTDKPTTTQRPSTTKPV----NCPDEQKLCADGKTCIPQTD 195

  Fly   422 --------SQSSKEPSSVSASASTSSAASAGSSTISSGTMSSMS------GPCPAVVPPTDAITK 472
                    ...|.|..||.|:.........|    |||:..|.:      ..|..::..||.:..
Zfish   196 FCDGIQNCPDGSDEKPSVCATVCDGQFLLLG----SSGSFHSKNFSDDGLAACRWIIRVTDGLAI 256

  Fly   473 RPGPPEPPLRQANVFDPVETGSRGHPPPPLTVRNKLGRNKPPPITYPRMQQRQDSTLSSDSYSIS 537
            :           .:|...:|                    ...:.:..:.:...||.:...:...
Zfish   257 K-----------LIFHTFDT--------------------EQDLDFLALYEGIGSTKTLAYFLSG 290

  Fly   538 SSPG------------YNSKLMEAPLLGSQQG------------------------------GRK 560
            :|||            :||:      .|::||                              .::
Zfish   291 TSPGDLWLLSHEATAEFNSQ------TGNRQGFNATYMAVNISDFSNEEKINCSFEEDFCLWRKE 349

  Fly   561 SNAPGS---AQRQTPLMDLAPTRFLGGAGGGTGSGKQGPAMPPPRSKINFRQDSTISSDSFSQTS 622
            .|..|.   ||.:||..|..|      :...|...:.|..:..||:..|:.:..
Zfish   350 LNDDGEWVRAQGETPPSDTGP------SFDHTTGNQSGYYIVTPRTSGNWERKF----------- 397

  Fly   623 SPGYNPKLMEAPLLPSLSAKRLCSAPAPIVCRQGVQH---EPIEEL----EPPQTISPLHKAAGQ 680
                  :|...||.|:          ..::|.|...|   |.:..|    |...||:.|.:..|.
Zfish   398 ------RLYSLPLTPT----------KELMCLQFWYHMFGEHVRRLTVTSEGRSTITVLFQKEGN 446

  Fly   681 PS------------SLQTIVRFQNGAPHTMSLQHQIINRRKSSNPYITNGRLKFRLFQILINAFA 733
            ..            |..|:|.|:               .:|||.
Zfish   447 YGDNWNYGQATLNISADTVVVFE---------------AQKSSG--------------------- 475

  Fly   734 LLAIAGGLAAYFNAYPTIKFVNKTIINTIHVEDTTSFGKNPAPGTCLPIIVRFCQGPQIPYNYTV 798
                                    |:|.|.::|.:.     .||:|          .|||.:.|.
Zfish   476 ------------------------ILNDIALDDISI-----VPGSC----------EQIPPDPTP 501

  Fly   799 FPNYIGHFGQLETQTDLDSYEALVDVRCYELVSLFLCTLFVPKCGQSGATVPPCKTLCTETMRRC 863
            .|..:..........||           ||..|.|....:....|.:.:        |..|
Zfish   502 VPPPVNPPEDCGGPFDL-----------YEPNSTFSSPNYPDGYGHNAS--------CMWT---- 543

  Fly   864 GFFFDVFGLSLPEYLNCKL-FKDFPSSEDCVGLDEVREVM--RAATHPKCD--GFQCDQNRCLPQ 923
                    |...|..|.:| |:|       |.|:...:|:  |....|..|  |....: |..|.
Zfish   544 --------LHAKEGQNIQLHFQD-------VALEASYDVLEIRDGVEPYSDLLGVLTGE-RSFPD 592

  Fly   924 EYVCDGHLDCMDQADEAKCER-----------------CGPDEIYCGDSQCIGTKHICDGIIDCP 971
            .:.....:..|...|.....|                 |...:..||...|:....:|||:.|||
Zfish   593 LFSTTSQMTVMLFTDAKTNNRGFLANFSAGVNLGQPDPCPSGQFQCGAGACVFNASVCDGVEDCP 657

  Fly   972 YGQDERNCLRLSERNGDVGTGVLEVYRIGQRQWMPACVKNWDRAVSPSAVCSILGYSAVNATSVL 1036
            .|.||.:|:.:.:.| ..||..|::..  |......|.::|....| ...|..|||.:..|:..:
Zfish   658 NGTDEADCVHVIKDN-TTGTERLKLQI--QNNLYTVCAQDWTPQFS-DFFCRYLGYRSGVASFSI 718

  Fly  1037 TQLTHRPLLATVNVSTDIWKMYAKRKSTLMQEFANCKKTEDYPMADLTCSNYECGRVKRGRHKPS 1101
            |.....| ..||||::: ..:..|.....:.|          .:..|.|:|..||    .|..||
Zfish   719 TVEGDGP-FTTVNVNSN-GSLELKPSDKCLSE----------KIVSLHCNNQPCG----VRKVPS 767

  Fly  1102 R-------------RIIGGTQASPGNWPFLAAI--LGGPEKIFYCAGVLISDQWVLTASHCVGNY 1151
            :             |::||..|..|.||::.::  |||    ..|...||..:|::||:|||...
Zfish   768 KSKIIEETDGKKEGRVVGGQDAQRGAWPWMVSLQWLGG----HACGATLIDREWLITAAHCVYGR 828

  Fly  1152 SVIDLEDWTIQLGV-TRRNSFTYSGQKVKVKAVIPHPQYNMAIAHDNDIALFQLATRVAFHEHLL 1215
            :| .|.:|...||: .:..:...:.|...|..||.|..||.. ..::|.||..|.|.|::.:::.
Zfish   829 NV-QLSNWAAVLGLHAQFETINPNKQVFSVDQVIMHKHYNKR-TKESDFALMHLKTPVSYTDYVQ 891

  Fly  1216 PVCLPPPSVRNLHPGTLCTVIGWGKREDKDPKSTYEYIVNEVQVPIITRNQCDEWLDNLTVSEGM 1280
            |:|||.|.. :...|..|.:.|||...:...|:.   ::.:..||:::..||.:||.....:|.|
Zfish   892 PICLPDPGA-HFEEGRKCFIAGWGLLSESGLKAD---VLQQAVVPLLSNTQCQKWLPEYNFTERM 952

  Fly  1281 VCAGFDDGGKDACQGDSGGPLLCPYPGEKNRWFVGGIVSWGIMCAHPRLPGVYANVVQYVPWIQE 1345
            :|||:.:||.|.|||||||||:|.   |:..|.:.|..|:||.|..|:.||.||.|.|:|.|:.|
Zfish   953 MCAGYAEGGVDTCQGDSGGPLMCE---EEGHWVLVGATSFGIGCGRPQRPGAYARVSQFVDWVAE 1014

  Fly  1346  1345
            Zfish  1015  1014

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Corin	NP_610297.2	CRD_FZ	778..894	CDD:143549	21/116 (18%)
		LDLa	911..942	CDD:238060	6/32 (19%)
		LDLa	945..979	CDD:238060	13/33 (39%)
		SR	980..>1034	CDD:214555	13/53 (25%)
		Tryp_SPc	1104..1346	CDD:238113	88/245 (36%)
tmprss15	XP_068072228.2	None