Protein Alignment Corin and tmprss12

DIOPT Version :10

• Sequence 1: NP_610297.2
• Gene: Corin / 35691
• FlyBaseID: FBgn0033192
• Length: 1397
• Species: Drosophila melanogaster
• Sequence 2: XP_031751504.1
• Gene: tmprss12 / 100127698
• XenbaseID: XB-GENE-964846
• Length: 324
• Species: Xenopus tropicalis
• Alignment Length: 313
• Identity: 109/313 - (34%)
• Similarity: 149/313 - (47%)
• Gaps: 52/313 - (16%)

  Fly  1079 PMADLTCS-----------NYECGRVKRGRHKPSRRIIGGTQASPGNWPFLAAI-----LGGPEK 1127
            ||..||.|           :..||.... .|.|..||:||..|.||.||:..::     |.|
 Frog     6 PMLHLTLSLCWLGIIQAIDSEVCGEPPL-VHTPGSRIVGGRNALPGAWPWQVSLQYFRTLSG--- 66

  Fly  1128 IFY---CAGVLISDQWVLTASHCV-GNYSVIDLEDWTIQLGVTRRNSFTYSGQ--KVKVKAVIPH 1186
              |   |.|.||.:.|||:|:||. .|.:.   |.|...||:  .|.|.....  |.|:|.:|.|
 Frog    67 --YSHRCGGSLIQNNWVLSAAHCFRANRNP---EYWRAVLGL--HNIFMEGSPVVKAKIKQIIIH 124

  Fly  1187 PQYNMAIAHDNDIALFQLATRVAFHEHLLPVCL----PPPSVRNLHPGTLCTVIGWGKREDKDPK 1247
            ..|: .||..|||||..|...|.:.:::.||||    .|.|:      |.|.:.|||..::   |
 Frog   125 ASYD-HIAITNDIALLLLHDFVTYSDYIHPVCLGSVTVPDSL------TACFITGWGVTKE---K 179

  Fly  1248 STYEYIVNEVQVPIITRNQCDEWLD-NLTVSEGMVCAGFDDGGKDACQGDSGGPLLCPYPGEKNR 1311
            .:...|:.|..|..|..::|:.... |..:::.|:|||.:.|..|:||||||||.:| |..|:.|
 Frog   180 GSISVILQEALVQTIPYSECNSSSSYNGFITQSMICAGDNSGAVDSCQGDSGGPFVC-YNTERMR 243

  Fly  1312 WFVGGIVSWGIMCAHPRLPGVYANVVQYVPWIQEQIAKHSRPIKE---DRVNK 1361
            ::..||.|:|..|..|..||||..|..||.||:..:|.......|   :|.||
 Frog   244 FYQMGITSFGYGCGKPNFPGVYTKVESYVSWIKAHMAYEKTSNTEWSPERQNK 296

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Corin	NP_610297.2	CRD_FZ	778..894	CDD:143549
		LDLa	911..942	CDD:238060
		LDLa	945..979	CDD:238060
		SR	980..>1034	CDD:214555
		Tryp_SPc	1104..1346	CDD:238113	94/257 (37%)
tmprss12	XP_031751504.1	Tryp_SPc	41..278	CDD:238113	94/257 (37%)