DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Corin and zgc:165423

DIOPT Version :9

Sequence 1:	NP_610297.2	Gene:	Corin / 35691	FlyBaseID:	FBgn0033192	Length:	1397	Species:	Drosophila melanogaster
Sequence 2:	XP_005164170.1	Gene:	zgc:165423 / 100101646	ZFINID:	ZDB-GENE-070720-11	Length:	538	Species:	Danio rerio

Alignment Length:	314	Identity:	107/314 - (34%)
Similarity:	157/314 - (50%)	Gaps:	40/314 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly  1055 WKMYAKRKSTLMQEFANCKKTEDYPMADLTCSNYECGRVKRGRHKPSRRIIGGTQASPGNWPFLA 1119
            ||:......||:....:|:.|:..|         .||:...     :.:|:|||.||.|:||:.|
Zfish     3 WKLSLLCVVTLLSTGCDCQPTQSPP---------ACGKAPL-----NTKIVGGTNASAGSWPWQA 53

  Fly  1120 AILGGPEKIFYCAGVLISDQWVLTASHCVGNYSVIDLEDWTIQLGVTRRNSFTYSGQKVKVKAVI 1184
            ::  ......:|.|.||||||:|:|:||..  |..:..|:|:.||...::....:.....|..||
Zfish    54 SL--HESGSHFCGGSLISDQWILSAAHCFP--SNPNPSDYTVYLGRQSQDLPNPNEVSKSVSQVI 114

  Fly  1185 PHPQYNMAIAHDNDIALFQLATRVAFHEHLLPVCLPPPSVRNLHPGTLCTVIGWGKRED----KD 1245
            .||.| ....||||:||..|::.|.|..::.||||.... ...:..|: .:.|||..|.    ..
Zfish   115 VHPLY-QGSTHDNDMALLHLSSPVTFSNYIQPVCLAADG-STFYNDTM-WITGWGTIESGVSLPS 176

  Fly  1246 PKSTYEYIVNEVQVPIITRNQCD-EWLDNLTVSEGMVCAGFDDGGKDACQGDSGGPLLCPYPGEK 1309
            |:     |:.||.|||:..|.|: .:....:::..|:|||...||||:||||||||::..   ..
Zfish   177 PQ-----ILQEVNVPIVGNNLCNCLYGGGSSITNNMMCAGLMQGGKDSCQGDSGGPMVIK---SF 233

  Fly  1310 NRWFVGGIVSWGIMCAHPRLPGVYANVVQYVPWIQEQIAKH------SRPIKED 1357
            |.|...|:||:|..||.|..|||||.|.||..||.:.:...      :.||::|
Zfish   234 NTWVQAGVVSFGKGCADPNYPGVYARVSQYQNWISQYVRASFIPVDVNAPIQDD 287

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Corin	NP_610297.2	CRD_FZ	778..894	CDD:143549
		LDLa	911..942	CDD:238060
		LDLa	945..979	CDD:238060
		SR	980..>1034	CDD:214555
		SRCR	992..1086	CDD:278931	7/30 (23%)
		Tryp_SPc	1103..1343	CDD:214473	93/244 (38%)
		Tryp_SPc	1104..1346	CDD:238113	95/246 (39%)
zgc:165423	XP_005164170.1	Tryp_SPc	37..267	CDD:214473	93/244 (38%)
		Tryp_SPc	38..269	CDD:238113	95/245 (39%)
		Tryp_SPc	299..473	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24253
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.010