Protein Alignment Corin and f7l

DIOPT Version :10

• Sequence 1: NP_610297.2
• Gene: Corin / 35691
• FlyBaseID: FBgn0033192
• Length: 1397
• Species: Drosophila melanogaster
• Sequence 2: NP_001083027.2
• Gene: f7l / 100038778
• ZFINID: ZDB-GENE-070424-102
• Length: 431
• Species: Danio rerio
• Alignment Length: 536
• Identity: 153/536 - (28%)
• Similarity: 221/536 - (41%)
• Gaps: 131/536 - (24%)

  Fly   829 LVSLFLCTLFVPKCGQSGATVPPCKTLCTET-------MRRCGFFFDVFGLSLPEYLNCKLFKDF 886
            |:.:.:.||.   ||...|..|.......|.       :||...|.:...|...| ..|
Zfish     9 LIQILIVTLV---CGSVCAGRPSVFLSRAEANRPLHPRVRRANSFLEELKLGDLE-REC------ 63

  Fly   887 PSSEDCVGLDEVREVMRAATHP-KCDGF---QCDQNRCLPQEYVCDGHLDCMDQADEAKCERCGP 947
              .|:....:|.||:.   |.| :.:.|   ..:.:.|  |...|.....|:||
Zfish    64 --LEEICSYEEAREIF---TVPDQLEDFWKRYTEVDHC--QSEPCQNGATCVDQ----------- 110

  Fly   948 DEIYCGDSQCIGTKHICDGIIDCPYGQDERNCLRLSERNGDVGTGVLEVYRIGQRQWMPACVKNW 1012
                      |.| :||    .||...:.|:|.:........|.    :||.|..:..  ||:.
Zfish   111 ----------INT-YIC----ICPVNLEGRHCDKEISPRSSFGC----LYRNGGCEHF--CVET- 153

  Fly  1013 DRAVSPSAVCSILGYSAVNATSVLTQLTHRPLLATVNVSTDIWKMYAKRKSTLMQEFANCKKTED 1077
                                    ::.||         |.|....|     ||..:.::|..|.|
Zfish   154 ------------------------SETTH---------SCDCAPGY-----TLHSDNSSCVPTAD 180

  Fly  1078 YPMADLTCSNYECGR-VKRGRHKPSRRIIGGTQASPGNWPFLAAI-LGGPEKIFYCAGVLISDQW 1140
                      :.||| |.:|   ...||:.|.....|..|:.|.: ..|..|   |.||:::.||
Zfish   181 ----------FSCGRPVAKG---VGPRIVKGDVCPKGQCPWQALLEYDGQYK---CGGVILNSQW 229

  Fly  1141 VLTASHCVGNYSVIDLEDWTIQLGVTRRNSFTYSGQKVKVKAVIPHPQYNMAIAHDNDIALFQLA 1205
            ::||:||:.......|:   :.:|...|:....:.|..||..|..|||||.: :.|:|:||.:|.
Zfish   230 IITAAHCIWRKDPALLQ---VIVGEHIRDRDEGTEQMRKVSEVFLHPQYNHS-STDSDVALLRLH 290

  Fly  1206 TRVAFHEHLLPVCLPPPS---VRNLHPGTLCTVIGWGKREDKDPKSTYEYIVNEVQVPIITRNQC 1267
            ..|....:.||||||||:   .|.|....:.||.|||:.....|.||   ::..:|||.::...|
Zfish   291 RPVTLGPYALPVCLPPPNGTFSRTLASIRMSTVSGWGRLAQSGPPST---VLQRLQVPRVSSEDC 352

  Fly  1268 DEWLDNLTVSEGMVCAGFDDGGKDACQGDSGGPLLCPYPGEKNRWFVGGIVSWGIMCAHPRLPGV 1332
             .....||||..|:||||.:||:|:|||||||||:..|   :|.||:.||||||..||...:.|:
Zfish   353 -RARSGLTVSRNMLCAGFAEGGRDSCQGDSGGPLVTRY---RNTWFLTGIVSWGKGCARADVYGI 413

  Fly  1333 YANVVQYVPWIQEQIA 1348
            |..|..:|.||.:.:|
Zfish   414 YTRVSVFVEWILKTVA 429

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Corin	NP_610297.2	CRD_FZ	778..894	CDD:143549	15/71 (21%)
		LDLa	911..942	CDD:238060	7/33 (21%)
		LDLa	945..979	CDD:238060	7/33 (21%)
		SR	980..>1034	CDD:214555	6/53 (11%)
		Tryp_SPc	1104..1346	CDD:238113	95/245 (39%)
f7l	NP_001083027.2	Gla	51..91	CDD:459861	10/51 (20%)
		EGF_CA	93..127	CDD:238011	13/61 (21%)
		FXa_inhibition	139..175	CDD:464251	12/80 (15%)
		Tryp_SPc	195..427	CDD:238113	95/245 (39%)