DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Corin and sfrpx

DIOPT Version :9

Sequence 1:	NP_610297.2	Gene:	Corin / 35691	FlyBaseID:	FBgn0033192	Length:	1397	Species:	Drosophila melanogaster
Sequence 2:	NP_001090810.1	Gene:	sfrpx / 100037908	XenbaseID:	XB-GENE-495296	Length:	288	Species:	Xenopus tropicalis

Alignment Length:	161	Identity:	44/161 - (27%)
Similarity:	60/161 - (37%)	Gaps:	28/161 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   773 NPAPGTCLPII-----------------VRFCQGPQIPYNYTVFPNYIGHFGQLETQTDLDSYEA 820
            |..|...||.|                 :..|.|  :.|:....||.:||....|......|:..
Frog    13 NLCPSAALPFILTQLSTRKSSCKAIPSSMTLCHG--VGYSEMRLPNLLGHDTMKEVLQQAGSWVP 75

  Fly   821 LVDVRCYELVSLFLCTLFVPKC-GQSGATVPPCKTLCTETMRRCGFFFDVFGLSLPEYLNCKLFK 884
            |:..:|:.....|||:||.|.| .:....|.||::||......|......||...|:..||   .
Frog    76 LLTKQCHADTKKFLCSLFAPVCLSELEEAVYPCRSLCEAVRDGCTPVMAAFGFPWPDMFNC---T 137

  Fly   885 DFP-SSEDCV----GLDEVREVMRAATHPKC 910
            .|| .:|.||    ..|:.:||...|....|
Frog   138 QFPLGNELCVPPAGSEDKQQEVKEEAPCSAC 168

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Corin	NP_610297.2	CRD_FZ	778..894	CDD:143549	37/138 (27%)
		LDLa	911..942	CDD:238060	44/161 (27%)
		LDLa	945..979	CDD:238060
		SR	980..>1034	CDD:214555
		SRCR	992..1086	CDD:278931
		Tryp_SPc	1103..1343	CDD:214473
		Tryp_SPc	1104..1346	CDD:238113
sfrpx	NP_001090810.1	CRD_FZ	30..157	CDD:413323	35/131 (27%)
sfrpx	NP_001090810.1	NTR_Sfrp1_like	162..288	CDD:239635	2/7 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000