DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1598 and get3

DIOPT Version :9

Sequence 1:	NP_610296.2	Gene:	CG1598 / 35690	FlyBaseID:	FBgn0033191	Length:	336	Species:	Drosophila melanogaster
Sequence 2:	NP_001002298.1	Gene:	get3 / 325704	ZFINID:	ZDB-GENE-040625-120	Length:	341	Species:	Danio rerio

Alignment Length:	335	Identity:	228/335 - (68%)
Similarity:	282/335 - (84%)	Gaps:	5/335 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 ADNLEPLEPSLQNLVEQDSLKWIFVGGKGGVGKTTCSSSLAVQLSKVRESVLIISTDPAHNISDA 66
            |.::|||||:|:|::||.|||||||||||||||||||.||||||:.|||||||||||||||||||
Zfish    12 APDVEPLEPTLKNIIEQKSLKWIFVGGKGGVGKTTCSCSLAVQLAAVRESVLIISTDPAHNISDA 76

  Fly    67 FDQKFTKVPTKVNGFDNLFAMEIDPNAGLNELPEEYFDGENEALRVSKGVMQEMINALPGIDEAM 131
            |||||:||||||.|:||||||||||:.|:.|||:|:|: |:..|.:.|.:|||.::|.|||||||
Zfish    77 FDQKFSKVPTKVKGYDNLFAMEIDPSLGVAELPDEFFE-EDNMLSMGKKMMQEAMSAFPGIDEAM 140

  Fly   132 SYAEVMKLVKGMNFSVVVFDTAPTGHTLRLIAFPQVVEKGLGKLLRLKMKVAPLLSQFVSMLGMA 196
            ||||||:|||||||||||||||||||||||:.||.:||:|||:|:::|.:::|.:||..:|||:.
Zfish   141 SYAEVMRLVKGMNFSVVVFDTAPTGHTLRLLNFPTIVERGLGRLMQIKNQISPFISQMCNMLGLG 205

  Fly   197 DVNADTLSQKLDDMLRVITQVNEQFKNPDQTTFVCVCIAEFFSLYETERLVQELTKCGIDVHNII 261
            |:|||.|:.||::.|.||..|:||||:|:||||:|||||||.||||||||:|||.||.||.||||
Zfish   206 DMNADQLASKLEETLPVIRSVSEQFKDPEQTTFICVCIAEFLSLYETERLIQELAKCRIDTHNII 270

  Fly   262 VNQLLFLQNSHDSCSMCASRFKIQEKYLDQIADLYEDFHVTKLPLLEKEVRGPESIRSFSENLMK 326
            ||||:|..|.. .|.||.:|.|||.|||||:.|||||||:.|||||..||||.:.:.:||:.|::
Zfish   271 VNQLVFPDNER-PCKMCEARHKIQSKYLDQMEDLYEDFHIVKLPLLPHEVRGADKVNTFSKQLLE 334

  Fly   327 PYNPKGEPKE 336
            ||:|   ||:
Zfish   335 PYSP---PKK 341

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1598	NP_610296.2	ArsA_ATPase	21..326	CDD:280525	212/304 (70%)
CG1598	NP_610296.2	ArsA	37..330	CDD:223082	198/292 (68%)
get3	NP_001002298.1	ArsA_ATPase	31..334	CDD:396792	212/304 (70%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170594226
Domainoid	1	1.000	435	1.000	Domainoid score	I552
eggNOG	1	0.900	-	-		E1_COG0003
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H31513
Inparanoid	1	1.050	470	1.000	Inparanoid score	I1480
OMA	1	1.010	-	-		QHG60619
OrthoDB	1	1.010	-	-		D401779at33208
OrthoFinder	1	1.000	-	-		FOG0004079
OrthoInspector	1	1.000	-	-		oto40610
orthoMCL	1	0.900	-	-		OOG6_100709
Panther	1	1.100	-	-	LDO	PTHR10803
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R486
SonicParanoid	1	1.000	-	-		X2829
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	17	16.800