Protein Alignment Gpo2 and glpA

DIOPT Version :10

• Sequence 1: NP_610295.1
• Gene: Gpo2 / 35689
• FlyBaseID: FBgn0033190
• Length: 713
• Species: Drosophila melanogaster
• Sequence 2: NP_416744.1
• Gene: glpA / 946713
• ECOCYCID: EG10391
• Length: 542
• Species: Escherichia coli
• Alignment Length: 606
• Identity: 134/606 - (22%)
• Similarity: 217/606 - (35%)
• Gaps: 163/606 - (26%)

  Fly    56 DILIIGGGAVGSGCALDAATRGLKTALVEANDFGSGTSSKSSKLLHGGLR----DLEQAISRLDV 116
            |::||||||.|:|.|.|.|.|||:..|||.:|..:|.:.::..|||.|.|    |.|.|
E. coli    10 DVIIIGGGATGAGIARDCALRGLRVILVERHDIATGATGRNHGLLHSGARYAVTDAESA------ 68

  Fly   117 AAFRRVRCSLQERSHIGKLAPHLSQPVPILLPVHHWWQAPLYYMKLKIYHLMAPKATRSFQ--YL 179
                  |..:.|...:.::|.|..:|...|.                   :..|:...|||  ::
E. coli    69 ------RECISENQILKRIARHCVEPTNGLF-------------------ITLPEDDLSFQATFI 108

  Fly   180 SADD-----ALEVFPMLRR-------QELFGAFVFYEGQHDDARMCLSVALTAARYGADICNHMK 232
            .|.:     |..:.|...|       ..|.||....:|..|..|:..:..|.|..:||.|....:
E. coli   109 RACEEAGISAEAIDPQQARIIEPAVNPALIGAVKVPDGTVDPFRLTAANMLDAKEHGAVILTAHE 173

  Fly   233 VSRLIKNKDGNVAGAEAVDQLTGKKYSIRAKVVVNATGHMSDSLRQMEDSEAKPLCTRSWSSIIV 297
            |:.||: :...|.|....:.|||:..::.|.|||||.|.....:.:..|...:....:  .|:::
E. coli   174 VTGLIR-EGATVCGVRVRNHLTGETQALHAPVVVNAAGIWGQHIAEYADLRIRMFPAK--GSLLI 235

  Fly   298 MPRFYCPEEVGVFDPHT------PSGRSIFFLPWQGHTLVGSSDEPLNLPE-QDTQPTETDVQSL 355
            |..        ..:.|.      ||...| .:|....:|:|::...::..| .|.:.|..:|..|
E. coli   236 MDH--------RINQHVINRCRKPSDADI-LVPGDTISLIGTTSLRIDYNEIDDNRVTAEEVDIL 291

  Fly   356 LDCVKHFVTPNFDVRRCDVLAVWGGYKPLPVQSDTLHHTRFKNHVIQL------GPRNMLSIVGG 414
            |...:.........|   :|..:.|.:||....|..........::.|      |....::|.||
E. coli   292 LREGEKLAPVMAKTR---ILRAYSGVRPLVASDDDPSGRNVSRGIVLLDHAERDGLDGFITITGG 353

  Fly   415 TWSSFRVLAEKTVNAAIR-YGDLSPLRKESVTAESCKLDGASGWSP-KMFIRLVQDFGMERDVAE 477
            ...::|::||...:|..| .|:..|     .|.....|.|:.  .| ::.:|.|
E. coli   354 KLMTYRLMAEWATDAVCRKLGNTRP-----CTTADLALPGSQ--EPAEVTLRKV----------- 400

  Fly   478 HLSNTYGSNAFKVAVSADSSGK----------AWPIVGKRLHSEFPYIEAEVKQGVRDFACTLED 532
                        :::.|...|.          ||...| |||              |...|..|.
E. coli   401 ------------ISLPAPLRGSAVYRHGDRTPAWLSEG-RLH--------------RSLVCECEA 438

  Fly   533 MVARRLRVAFLNVQV------------------AEEILPQVANIMAKELNWSRDQIKKQIRQTRT 579
            :.|..::.|..|:.|                  .|....:.|.::.:   ::.....:.|.|..|
E. coli   439 VTAGEVQYAVENLNVNSLLDLRRRTRVGMGTCQGELCACRAAGLLQR---FNVTTSAQSIEQLST 500

  Fly   580 FLNSQ--------MGQLTKES 592
            |||.:        .|...:||
E. coli   501 FLNERWKGVQPIAWGDALRES 521

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gpo2	NP_610295.1	DAO	8..583	CDD:477422	130/587 (22%)
		EF-hand_7	614..672	CDD:463900
glpA	NP_416744.1	glpA	25..536	CDD:236847	124/591 (21%)