Protein Alignment Gpo2 and GUT2

DIOPT Version :10

• Sequence 1: NP_610295.1
• Gene: Gpo2 / 35689
• FlyBaseID: FBgn0033190
• Length: 713
• Species: Drosophila melanogaster
• Sequence 2: NP_012111.1
• Gene: GUT2 / 854651
• SGDID: S000001417
• Length: 649
• Species: Saccharomyces cerevisiae
• Alignment Length: 622
• Identity: 207/622 - (33%)
• Similarity: 318/622 - (51%)
• Gaps: 86/622 - (13%)

  Fly    34 PQMKRELPT-------RKMCLEAFKRTH-YDILIIGGGAVGSGCALDAATRGLKTALVEANDFGS 90
            |....:.||       |:..|:...:|| :|:|||||||.|:|||||||||||..||||..||.|
Yeast    39 PSYMVQFPTAAPPQVSRRDLLDRLAKTHQFDVLIIGGGATGTGCALDAATRGLNVALVEKGDFAS 103

  Fly    91 GTSSKSSKLLHGGLRDLEQAISRLDVAAFRRVRCSLQERSHIGKLAPHLSQPVPILLPVHHWWQA 155
            ||||||:|::|||:|.||:|......|....|..:|.||.|:...||||...:|||:|::..||.
Yeast   104 GTSSKSTKMIHGGVRYLEKAFWEFSKAQLDLVIEALNERKHLINTAPHLCTVLPILIPIYSTWQV 168

  Fly   156 PLYYMKLKIYHLMAPKATRSFQYLSADDA-LEVFPMLRRQELFGAFVFYEGQHDDARMCLSVALT 219
            |..||..|.|...|........||.:..| :|..|||....|..:.|:::|..:|:|:..::|:|
Yeast   169 PYIYMGCKFYDFFAGSQNLKKSYLLSKSATVEKAPMLTTDNLKASLVYHDGSFNDSRLNATLAIT 233

  Fly   220 AARYGADICNHMKVSRLIKN-KDGNVAGAEAVDQLTGKKYSIRAKVVVNATGHMSDSLRQMEDSE 283
            |...||.:.|:::|.:|||: ..|.|.||||.|..|.:...|.||.||||||..||::.||:.:.
Yeast   234 AVENGATVLNYVEVQKLIKDPTSGKVIGAEARDVETNELVRINAKCVVNATGPYSDAILQMDRNP 298

  Fly   284 A----KPLCTRS-----WSSI---------------IVMPRFYCPEEVGVFDPHTPSGRSIFFLP 324
            :    .||...|     ::.|               ||:|.||||:::|:.|..|..||.:||||
Yeast   299 SGLPDSPLNDNSKIKSTFNQIAVMDPKMVIPSIGVHIVLPSFYCPKDMGLLDVRTSDGRVMFFLP 363

  Fly   325 WQGHTLVGSSDEPLNLPEQDTQPTETDVQSLLDCVKHFVTPNFDVRRCDVLAVWGGYKPL----- 384
            |||..|.|::|.||....::..|||.|:|.:|..::|::  .|.|:|.|||:.|.|.:||
Yeast   364 WQGKVLAGTTDIPLKQVPENPMPTEADIQDILKELQHYI--EFPVKREDVLSAWAGVRPLVRDPR 426

  Fly   385 --PVQSDTLHHTR--FKNHVIQLGPRNMLSIVGGTWSSFRVLAEKTVNAAIRYG---DLSPLRKE 442
              |........|:  .::|.:......:::|.||.|:::|.:||:||:..:..|   :|.|....
Yeast   427 TIPADGKKGSATQGVVRSHFLFTSDNGLITIAGGKWTTYRQMAEETVDKVVEVGGFHNLKPCHTR 491

  Fly   443 SVTAESCKLDGASGWSPKMFIRLVQDFGMERDVAEHLSNTYGSNA------FKVAVS-------A 494
            .:     ||.||..|:......|.|::.:...::.:|...||:.:      ||.::.       |
Yeast   492 DI-----KLAGAEEWTQNYVALLAQNYHLSSKMSNYLVQNYGTRSSIICEFFKESMENKLPLSLA 551

  Fly   495 DSSGKAWPIVGKRLHS------------EFPYIEAEVKQGVR-DFACTLEDMVARRLRVAFLNVQ 546
            |.....       ::|            .:|:...|:|..:: ::..|..|.:.||.|.|||:.:
Yeast   552 DKENNV-------IYSSEENNLVNFDTFRYPFTIGELKYSMQYEYCRTPLDFLLRRTRFAFLDAK 609

  Fly   547 VAEEILPQVANIMAKELNWSRDQIKKQIRQTRTFLNS 583
            .|...:.....:|..|.|||..:.:.::.:|..|:.:
Yeast   610 EALNAVHATVKVMGDEFNWSEKKRQWELEKTVNFIKT 646

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gpo2	NP_610295.1	DAO	8..583	CDD:477422	207/620 (33%)
		EF-hand_7	614..672	CDD:463900
GUT2	NP_012111.1	DAO	28..647	CDD:477422	207/622 (33%)