Protein Alignment Gpo2 and Gpd2

DIOPT Version :10

• Sequence 1: NP_610295.1
• Gene: Gpo2 / 35689
• FlyBaseID: FBgn0033190
• Length: 713
• Species: Drosophila melanogaster
• Sequence 2: NP_036868.1
• Gene: Gpd2 / 25062
• RGDID: 2726
• Length: 727
• Species: Rattus norvegicus
• Alignment Length: 729
• Identity: 310/729 - (42%)
• Similarity: 469/729 - (64%)
• Gaps: 41/729 - (5%)

  Fly     7 MAVMLGSSKLGHGAFGFDERQAD----------STPVPQMKRELPTRKMCLEAFKRT-HYDILII 60
            :|.:||.|:..|    :..:|..          |.||   .||.|:|:..|...:.| .:|||:|
  Rat    18 LATVLGLSQFAH----YRRKQVSLAYVEAATCFSEPV---NREPPSREAQLMTLQNTSEFDILVI 75

  Fly    61 GGGAVGSGCALDAATRGLKTALVEANDFGSGTSSKSSKLLHGGLRDLEQAISRLDVAAFRRVRCS 125
            ||||.|.||||||.||||||||||.|||.|||||:|:||:|||:|.|::||:.|||..:|.|:.:
  Rat    76 GGGATGCGCALDAVTRGLKTALVERNDFASGTSSRSTKLIHGGVRYLQKAITNLDVEQYRMVKEA 140

  Fly   126 LQERSHIGKLAPHLSQPVPILLPVHHWWQAPLYYMKLKIYHLMA-PKATRSFQYLSADDALEVFP 189
            |.||:::.::|||||.|:||:||::.|||.|.|::.:|:|.|:| ....:|...||...|||.||
  Rat   141 LHERANLLEIAPHLSAPLPIMLPLYKWWQLPYYWVGIKMYDLVAGSHCLKSSYVLSKSRALEHFP 205

  Fly   190 MLRRQELFGAFVFYEGQHDDARMCLSVALTAARYGADICNHMKVSRLIKNKD-----GNVAGAEA 249
            ||::.:|.||.|:|:|||:||||.|::|||||||||...|:|:|..|:|..|     ..|:||..
  Rat   206 MLQKDKLVGAIVYYDGQHNDARMNLAIALTAARYGAATANYMEVVSLLKKTDPETGKERVSGARC 270

  Fly   250 VDQLTGKKYSIRAKVVVNATGHMSDSLRQMEDSEAKPLCTRSWSSIIVMPRFYCPEEVGVFDPHT 314
            .|.|||.::::|||.|:||||..:||:|:|:|::..|:|..|....||||.:|.||.:|:.||.|
  Rat   271 KDVLTGHEFNVRAKCVINATGPFTDSVRKMDDNDVVPICQPSAGVHIVMPGYYSPENMGLLDPAT 335

  Fly   315 PSGRSIFFLPWQGHTLVGSSDEPLNLPEQDTQPTETDVQSLLDCVKHFVTPNFDVRRCDVLAVWG 379
            ..||.||||||:..|:.|::|.|.::..... |:|.|:..:|:.|:::::.:.:|||.||||.|.
  Rat   336 SDGRVIFFLPWEKMTIAGTTDSPTDVTHHPI-PSEDDINFILNEVRNYLSCDVEVRRGDVLAAWS 399

  Fly   380 GYKPL---PVQSDTLHHTRFKNHVIQLGPRNMLSIVGGTWSSFRVLAEKTVNAAIRYGDLS--PL 439
            |.:||   |..::|...:|  |||:::....:::|.||.|:::|.:||.|||.|::..:|:  |.
  Rat   400 GIRPLVTDPKSANTQSISR--NHVVEVSDSGLITIAGGKWTTYRSMAEDTVNKAVKLHNLNAGPS 462

  Fly   440 RKESVTAESCKLDGASGWSPKMFIRLVQDFGMERDVAEHLSNTYGSNAFKVAVSADSSGKAWPIV 504
            |...:.     |.|...|||.::||||||:|:|.:||:||:.|||..||.||..|..:||.||:|
  Rat   463 RTVGLF-----LQGGKDWSPTLYIRLVQDYGLESEVAQHLAKTYGDKAFDVAKMASVTGKRWPVV 522

  Fly   505 GKRLHSEFPYIEAEVKQGVRDFACTLEDMVARRLRVAFLNVQVAEEILPQVANIMAKELNWSRDQ 569
            |.||.|||||||||||.|::::|||..||::||.|:||||||.|||.||::..:|.:|||||..:
  Rat   523 GVRLVSEFPYIEAEVKYGIKEYACTAVDMISRRTRLAFLNVQAAEEALPKIVELMGRELNWSELR 587

  Fly   570 IKKQIRQTRTFLNSQMGQLTKESASQMSIPIKMSVRQVRKFAGQFRQMDDNNTGYVSIADCCKAM 634
            .::::.....||..:||..::......|..|.:....:.::..:|...|::..|:::|.|..:.:
  Rat   588 KQEELETATRFLYYEMGYKSRTEQLTDSTEISLLPPDIDRYKKRFHMFDEDEKGFITIVDVQRVL 652

  Fly   635 KTMGVKEVPVDLMHDVLRDIDVHAQGKVNLYEFLLLMSAIVQGNTEYLRYARLYLDHKRQMQGSN 699
            :::.| ::..|.:|::|.::|::..|:|.|:|||.||||:..|.....|.|.|.   |...:..:
  Rat   653 ESINV-QMDEDTLHEILCEVDLNKNGQVELHEFLQLMSAVHTGRVSGSRLAILM---KTAEENLD 713

  Fly   700 FPTVMQMERAGGGL 713
            ....:.::|:.|||
  Rat   714 RRVPIPVDRSCGGL 727

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gpo2	NP_610295.1	DAO	8..583	CDD:477422	277/596 (46%)
		EF-hand_7	614..672	CDD:463900	17/57 (30%)
Gpd2	NP_036868.1	DAO	1..599	CDD:477422	275/595 (46%)
		EFh	627..689	CDD:238008	17/62 (27%)