Protein Alignment Drat and MECR

DIOPT Version :9

• Sequence 1: NP_610293.3
• Gene: Drat / 35687
• FlyBaseID: FBgn0033188
• Length: 434
• Species: Drosophila melanogaster
• Sequence 2: XP_011539841.1
• Gene: MECR / 51102
• HGNCID: 19691
• Length: 459
• Species: Homo sapiens
• Alignment Length: 344
• Identity: 71/344 - (20%)
• Similarity: 125/344 - (36%)
• Gaps: 118/344 - (34%)

  Fly   109 ITSMSSVSSEL-------SDYCPSVNSMSSPAH-------QGIREGSFFP------GFEVAGVIE 153
            |:|.|:|...|       ||.  .|..:::|.:       ||  ...|.|      |.|....:.
Human    81 ISSASTVLKNLELAAVRGSDV--RVKMLAAPINPSDINMIQG--NYGFLPELPAVGGNEGVAQVV 141

  Fly   154 SLGSEITEANNRGLRIGQRVIVYPFD------ETPAGYAELLVVPDLKHVVPIPDSLPMEVAAML 212
            ::||.:|     ||:.|..||  |.:      .|.|.::|       :.::.:|..:|::.||.|
Human   142 AVGSNVT-----GLKPGDWVI--PANAGLGTWRTEAVFSE-------EALIQVPSDIPLQSAATL 192

  Fly   213 PTGALLAWNAVFKAQAVVTQILSQRAATEPKRKPKILIV---GTGGLALWAVRIASYHFATTGAD 274
            ......|:..:...:.:               :|...::   ...|:....::||    |..|..
Human   193 GVNPCTAYRMLMDFEQL---------------QPGDSVIQNASNSGVGQAVIQIA----AALGLR 238

  Fly   275 NVDITVASLRDEGFRLATEIKNVSVVQWNECLYEPQLIERTKDVCGGAVDVVIDFGTTSRSLHR- 338
            .:::    :||.     .:|:.:|              :|.|.:  ||..|:     |...|.|
Human   239 TINV----VRDR-----PDIQKLS--------------DRLKSL--GAEHVI-----TEEELRRP 273

  Fly   339 SMHCLSKGGVVLISDEVAEKLLPKFSRLSEQYQQEIIAISNGTAEQLAELVELVANKK----IEP 399
            .|....|         :.:..|.|...|::.:     .:..|:.|  :||..:..|.|    .||
Human   274 EMKNFFK---------IRKLRLRKEEMLNQNH-----IVYKGSRE--SELASVSPNSKPLNLPEP 322

  Fly   400 PPHSVFPCEQAAEVIAKLC 418
            |||:: |....|...::||
Human   323 PPHNM-PRHAPATACSQLC 340

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Drat	NP_610293.3	Qor	142..430	CDD:223677	60/297 (20%)
		MDR	144..428	CDD:302572	59/295 (20%)
MECR	XP_011539841.1	ETR	44..459	CDD:176250	71/344 (21%)
		Qor	100..>269	CDD:223677	43/235 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0604
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900