Protein Alignment Drat and CRYZ

DIOPT Version :10

• Sequence 1: NP_610293.3
• Gene: Drat / 35687
• FlyBaseID: FBgn0033188
• Length: 434
• Species: Drosophila melanogaster
• Sequence 2: NP_001880.2
• Gene: CRYZ / 1429
• HGNCID: 2419
• Length: 329
• Species: Homo sapiens
• Alignment Length: 326
• Identity: 76/326 - (23%)
• Similarity: 130/326 - (39%)
• Gaps: 74/326 - (22%)

  Fly   131 SPAHQGIREGS--------FFPGFEVAGVIESLGSEITEANNRGLRIGQRVIVYPFDETPAGYAE 187
            :|....||.|:        :.||.:||||||::|.     |....:.|.|  |:.......||||
Human    48 NPVETYIRSGTYSRKPLLPYTPGSDVAGVIEAVGD-----NASAFKKGDR--VFTSSTISGGYAE 105

  Fly   188 LLVVPDLKHVV-PIPDSLPMEVAAMLPTGALLAWNAVFKAQAVVTQILSQRAATEPKRKPKILIV 251
            ..:..|  |.| .:|:.|..:..|.:......|:.|:..:..|             |....:|:.
Human   106 YALAAD--HTVYKLPEKLDFKQGAAIGIPYFTAYRALIHSACV-------------KAGESVLVH 155

  Fly   252 G-TGGLALWAVRIA-SYHFATTGADNVDITVASLRDEGFRLATEIKNVSVVQWNECLYEPQLIER 314
            | :||:.|.|.:|| :|.....|....        :||.::..:.....|....|..|    |::
Human   156 GASGGVGLAACQIARAYGLKILGTAGT--------EEGQKIVLQNGAHEVFNHREVNY----IDK 208

  Fly   315 TKDVCG-GAVDVVIDFGTTSRSLHRSMHCLSKGG-VVLISDEVAEKLLPK--------------F 363
            .|...| ..:|::|:. ..:.:|.:.:..||.|| |:::......::.|:              |
Human   209 IKKYVGEKGIDIIIEM-LANVNLSKDLSLLSHGGRVIVVGSRGTIEINPRDTMAKESSIIGVTLF 272

  Fly   364 SRLSEQYQQEIIAISNGTAEQLAELVELVANKKIEPPPHSVFPCEQAAEVIAKLCN-SEIPGRAI 427
            |...|::||...|:..|        :|:   ..::|...|.:|.|:.||....:.: |...|:.|
Human   273 SSTKEEFQQYAAALQAG--------MEI---GWLKPVIGSQYPLEKVAEAHENIIHGSGATGKMI 326

  Fly   428 L 428
            |
Human   327 L 327

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Drat	NP_610293.3	MDR	144..428	CDD:450120	70/303 (23%)
CRYZ	NP_001880.2	zeta_crystallin	8..329	CDD:176215	76/326 (23%)