Protein Alignment Drat and ADH7

DIOPT Version :10

• Sequence 1: NP_610293.3
• Gene: Drat / 35687
• FlyBaseID: FBgn0033188
• Length: 434
• Species: Drosophila melanogaster
• Sequence 2: NP_001159976.1
• Gene: ADH7 / 131
• HGNCID: 256
• Length: 394
• Species: Homo sapiens
• Alignment Length: 325
• Identity: 67/325 - (20%)
• Similarity: 106/325 - (32%)
• Gaps: 115/325 - (35%)

  Fly    90 RIRIVCAGACYRRRDRANSITSMSSVSSELSDYCPSVNSMSSPAHQGIREGSFFP---GFEVAGV 151
            ||:|:..|.| |..|.....|.:|.                            ||   |.|..|:
Human    58 RIKILATGIC-RTDDHVIKGTMVSK----------------------------FPVIVGHEATGI 93

  Fly   152 IESLGSEIT-----------------EAN-------NRGLR---IGQRVI-------------VY 176
            :||:|..:|                 |.|       |..:|   .|:.|:             |:
Human    94 VESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGTTRFTCKGKPVH 158

  Fly   177 PFDETPAGYAELLVVPDLKHVVPIPDSLPMEVAAMLPTGALLAWNAVFKAQAVVTQILSQRAATE 241
            .|..| :.:.|..|| |...|..|.|:.|.|...::..|....:.|..|...|
Human   159 HFMNT-STFTEYTVV-DESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTGKV------------ 209

  Fly   242 PKRKP--KILIVGTGGLALWAVRIASYHFATTGADNVDITVASLRDEGFRLATEIKNVSVVQWNE 304
               ||  ..::.|.||:.|..:....    :.||..: |.:...:|       :.:....|...|
Human   210 ---KPGSTCVVFGLGGVGLSVIMGCK----SAGASRI-IGIDLNKD-------KFEKAMAVGATE 259

  Fly   305 CLYEPQ---------LIERTKDVCGGAVDVVIDFGTTSRSLHRSMHCLSKGGVVLISDEVAEKLL 360
            |: .|:         |.|.|.:..|...:|:....|...:| .|.| ::.|..|::....:.|:|
Human   260 CI-SPKDSTKPISEVLSEMTGNNVGYTFEVIGHLETMIDAL-ASCH-MNYGTSVVVGVPPSAKML 321

  Fly   361  360
            Human   322  321

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Drat	NP_610293.3	MDR	144..428	CDD:450120	57/271 (21%)
ADH7	NP_001159976.1	alcohol_DH_class_I_II_IV	27..394	CDD:176259	67/325 (21%)