Protein Alignment Drat and ADH5

DIOPT Version :9

• Sequence 1: NP_610293.3
• Gene: Drat / 35687
• FlyBaseID: FBgn0033188
• Length: 434
• Species: Drosophila melanogaster
• Sequence 2: NP_000662.3
• Gene: ADH5 / 128
• HGNCID: 253
• Length: 374
• Species: Homo sapiens
• Alignment Length: 390
• Identity: 82/390 - (21%)
• Similarity: 126/390 - (32%)
• Gaps: 145/390 - (37%)

  Fly    81 IEDTP--ALGARIRIVCAGACYRRRDRANSITSMSSVSSELSDYCPSVNSMSSPAHQGIREGSFF 143
            ||..|  |...||:|:....|:         |...::|....:.|                   |
Human    25 IEVAPPKAHEVRIKIIATAVCH---------TDAYTLSGADPEGC-------------------F 61

  Fly   144 P---GFEVAGVIESLGSEITE----------------------------------ANNRGLR--- 168
            |   |.|.||::||:|..:|:                                  ...:||.
Human    62 PVILGHEGAGIVESVGEGVTKLKAGDTVIPLYIPQCGECKFCLNPKTNLCQKIRVTQGKGLMPDG 126

  Fly   169 ------IGQRVIVYPFDETPAGYAELLVVPDLKHVVPIPDSLPMEVAAMLPTGALLAWNAVFKAQ 227
                  .|:.::.|....|   ::|..||.|:. |..|....|::...:|..|....:.|
Human   127 TSRFTCKGKTILHYMGTST---FSEYTVVADIS-VAKIDPLAPLDKVCLLGCGISTGYGA----- 182

  Fly   228 AVVTQILSQRAATEPKRKPKILIVGTGGLA-LWAVRIASYHFATTGADNVDITVASLRDEGFRLA 291
            ||.|      |..||.....:..:|..||| :...::|       ||..: |.|...:|: |..|
Human   183 AVNT------AKLEPGSVCAVFGLGGVGLAVIMGCKVA-------GASRI-IGVDINKDK-FARA 232

  Fly   292 TEIKNVSVVQWNECLYEPQ---------LIERTKDVCGGAVDVVIDFGTTSRSLHRSMHCLSKG- 346
            .|...      .||: .||         |||.|    .|.||...:.....:.:..::....||
Human   233 KEFGA------TECI-NPQDFSKPIQEVLIEMT----DGGVDYSFECIGNVKVMRAALEACHKGW 286

  Fly   347 ------GVVLISDEVAEKLLPKFSRLSEQYQQEIIAISNGTA-------EQLAELVELVANKKIE 398
                  ||....:|:|          :..:|........|||       |.:.:||....:|||:
Human   287 GVSVVVGVAASGEEIA----------TRPFQLVTGRTWKGTAFGGWKSVESVPKLVSEYMSKKIK 341

  Fly   399  398
            Human   342  341

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Drat	NP_610293.3	Qor	142..430	CDD:223677	71/327 (22%)
		MDR	144..428	CDD:302572	70/325 (22%)
ADH5	NP_000662.3	alcohol_DH_class_III	6..373	CDD:176260	82/390 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165145122
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.930