Protein Alignment Drat and ADH1C

DIOPT Version :9

• Sequence 1: NP_610293.3
• Gene: Drat / 35687
• FlyBaseID: FBgn0033188
• Length: 434
• Species: Drosophila melanogaster
• Sequence 2: NP_000660.1
• Gene: ADH1C / 126
• HGNCID: 251
• Length: 375
• Species: Homo sapiens
• Alignment Length: 394
• Identity: 73/394 - (18%)
• Similarity: 115/394 - (29%)
• Gaps: 162/394 - (41%)

  Fly    79 VPIEDTPALGARIRIVCAGACYRRRDRANSITSMSSVSSELSDYCPSVNSMSSPAHQGIREGSFF 143
            |.:....|...||::|.||.|  |.|.       ..||..|....|.:
Human    27 VEVAPPKAHEVRIKMVAAGIC--RSDE-------HVVSGNLVTPLPVI----------------- 65

  Fly   144 PGFEVAGVIESLGSEITE----------------------------------ANNRG-LRIGQR- 172
            .|.|.||::||:|..:|.                                  .|.|| |:.|.|
Human    66 LGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTRR 130

  Fly   173 -----------VIVYPFDETPAGYAELLVVPDLKHVVPIPDSLPMEVAAMLPTGALLAWNAVFKA 226
                       |.|..|.:        ..|.|...|..|..:.|:|...::..|....:.:..|.
Human   131 FTCSGKPIHHFVGVSTFSQ--------YTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKV 187

  Fly   227 QAVVTQILSQRAATEPKRKPKILIVGTGGLALWAVRIASYHFATTGADNVDITVASLRDEGFRLA 291
            ..|..      .:|       ..:.|.||:.|..|      .....|....|....:..:.|..|
Human   188 AKVTP------GST-------CAVFGLGGVGLSVV------MGCKAAGAARIIAVDINKDKFAKA 233

  Fly   292 TEIKNVSVVQWNECL----YEPQLIERTKDVCGGAVD--------------------------VV 326
            .|:..      .||:    |:..:.|..|::..|.||                          |:
Human   234 KELGA------TECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVI 292

  Fly   327 IDFGTTSRSLHRSMHCLSKG----GVV------------LISDEVAEK---------LLPKFSRL 366
            :.....|::|..:...|..|    |.:            |::|.:|:|         :|| |.::
Human   293 VGVPPDSQNLSINPMLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILP-FEKI 356

  Fly   367 SEQY 370
            :|.:
Human   357 NEGF 360

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Drat	NP_610293.3	Qor	142..430	CDD:223677	59/331 (18%)
		MDR	144..428	CDD:302572	59/329 (18%)
ADH1C	NP_000660.1	alcohol_DH_class_I_II_IV	3..375	CDD:176259	73/394 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165145119
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.930