Protein Alignment Orc1 and ORC1B

DIOPT Version :10

• Sequence 1: NP_477303.1
• Gene: Orc1 / 35686
• FlyBaseID: FBgn0286788
• Length: 924
• Species: Drosophila melanogaster
• Sequence 2: NP_192999.1
• Gene: ORC1B / 826875
• AraportID: AT4G12620
• Length: 813
• Species: Arabidopsis thaliana
• Alignment Length: 863
• Identity: 245/863 - (28%)
• Similarity: 384/863 - (44%)
• Gaps: 207/863 - (23%)

  Fly   180 KRSYRLIPLEIHLEQPEDNARPTRSSRKSLTAHRESKRSISARHD--DTAGN---KGSS-VEKRR 238
            ::||.......|..|..:...|.|.|.      |...|.|...:|  |..||   :|.: :.||.
plant    22 RKSYLSPSSTSHTPQTPETHTPLRRSA------RHVSRKIDLGNDPIDAPGNDPIEGMNLIRKRE 80

  Fly   239 RASMAASSSVEFIDVNSFICENKVSPIKIVGGRSVVRLSEKKNAPEINA---NYLPASPLTEKNA 300
            ||....::.|                        |...|:|...|:...   ::.|.||:..:..
plant    81 RAPRKPTTDV------------------------VPSKSKKTETPKKKKKIDSFTPVSPIRSETI 121

  Fly   301 KVETPKSRASAARRNL---------NLSLDRGADTTAD------------------------SDC 332
            |....|.|....:...         ::.:.|..|:.:|                        .||
plant   122 KKTKKKKRVYYNKVEFDETEFEIGDDVYVKRREDSNSDEEEDPEIEDCQICFKSDTNIMIECDDC 186

  Fly   333 LN--YSIVQQTPDPKTPSNDMKIKLRLSERRRSVRLASMDVDPLSLEEAVQEPNAQGRK-----R 390
            |.  :....:.|..:.|..|.  ..:..|.::|.:..::|         :.:| .:|:|     |
plant   187 LGGFHLKCLKPPLKEVPEGDW--ICQFCEVKKSGQSQTLD---------LPKP-PEGKKLARTMR 239

  Fly   391 LGVANGDIYHTPTKKSKEPLESAA---------ATEQTPSTRRKSILKSATSRLAEGTPRRSIHL 446
            ..:.:||::.....|..:.::...         ..|:|.|.|:...||            |.::|
plant   240 EKLLSGDLWAARIDKLWKEVDDGVYWIRARWYMIPEETVSGRQPHNLK------------RELYL 292

  Fly   447 SNIVEQRVFEDDEI--------ISTPK-------------------------------------- 465
            :|     .|.|.|:        :..||
plant   293 TN-----DFADIEMECILRHCSVKCPKEFSKASNDGDDVFLCEYEYDVHWRSFKRLAELADGDSD 352

  Fly   466 -----RGRSKKTVQDNDEDYSPKKSVQKTPTRTRRSSTTTKTATTPSKGITTATATPMTPSQKMK 525
                 .||.::.|.|:||:......|.|:   .|...|:.:......||....          ::
plant   353 SDQEWNGRKEEEVDDSDEEMELDDEVLKS---KRGGLTSARGGANSRKGRFFG----------VE 404

  Fly   526 KIRAGELSPSMQQRTDLPAKDSSKSELQLAREQLHVSVVPKSLPCREREFENIYAFLEGKI-QDQ 589
            |: ..:|.|.       ..:...:|||:.|:..|.::..|||||||.:|.|.|.:|::|.| .||
plant   405 KV-GMKLIPE-------HVRCHKQSELEKAKATLLLATRPKSLPCRSKEMEEITSFIKGSISDDQ 461

  Fly   590 C-GGCMYVSGVPGTGKTATVTGVIRTLQRMAKQNELPAFEYLEINGMRLTEPRQAYVQIYKQLTG 653
            | |.|||:.||||||||.:|..|::.|:...::..:..:.::||||::|..|...|..||:.|:|
plant   462 CLGRCMYIHGVPGTGKTISVLSVMKNLKAEVEEGSVSPYCFVEINGLKLASPENIYSVIYEALSG 526

  Fly   654 KTVSWEQAHALLEKRFTTPAPRRV------TTVLLVDELDILCNRRQDVVYNLLDWPTKSAAKLV 712
            ..|.|::|...|.:||.  ..:|:      ..:||:||||:|..|.|.|:||:||||||..:|||
plant   527 HRVGWKKALQCLNERFA--EGKRIGKEDEKPCILLIDELDLLVTRNQSVLYNILDWPTKPNSKLV 589

  Fly   713 VVTIANTMDLPERLLMGKVTSRLGLTRLTFQPYSHKQLQEIVTARLGGSETFKGEAVQLVARKVA 777
            |:.|||||||||:|| .:::||:|:.||.|.||:|.|||||::.||.|.:.|:..|::..:||||
plant   590 VLGIANTMDLPEKLL-PRISSRMGIQRLCFGPYNHTQLQEIISTRLNGIDAFEKTAIEFASRKVA 653

  Fly   778 AVSGDARRALDICRRATEIAD-------TAAVKCVTMLHVQQALAEMIASAKVQAIRNCSRMEQI 835
            |:||||||||:|||||.|:||       :|..:.|.|..|:.|:.||..:..:|.:::.|::.:|
plant   654 AISGDARRALEICRRAAEVADHRLNTNKSAKNQLVIMADVEAAIQEMFQAPHIQVMKSVSKLSKI 718

  Fly   836 FLQAIAAEVTRTGVEETTFMGVYQQVETIAAFMGVTFPPPGRALRLCSKLGAERLIISEHSRNDL 900
            ||.|:..|:.:||:.||||..|...|.:|....|..||.....|::...||..|:|:.|......
plant   719 FLTAMVHELYKTGMAETTFDRVATTVSSICLTNGEAFPGWDILLKIGCDLGECRIILCEPGEKHR 783

  Fly   901 FQKILLNVSADDIHYALR 918
            .||:.||..:||:.:||:
plant   784 LQKLQLNFPSDDVAFALK 801

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Orc1	NP_477303.1	BAH_Orc1p_animal	44..185	CDD:240070	2/4 (50%)
		PTZ00112	<559..795	CDD:240274	120/243 (49%)
		Cdc6_C	837..917	CDD:215013	27/79 (34%)
ORC1B	NP_192999.1	BAH_plant_2	189..344	CDD:240069	27/183 (15%)
		PTZ00112	<424..727	CDD:240274	137/305 (45%)