Protein Alignment Orc1 and cdc6

DIOPT Version :9

• Sequence 1: NP_477303.1
• Gene: Orc1 / 35686
• FlyBaseID: FBgn0286788
• Length: 924
• Species: Drosophila melanogaster
• Sequence 2: NP_001120805.1
• Gene: cdc6 / 402825
• ZFINID: ZDB-GENE-050506-131
• Length: 561
• Species: Danio rerio
• Alignment Length: 569
• Identity: 160/569 - (28%)
• Similarity: 263/569 - (46%)
• Gaps: 88/569 - (15%)

  Fly   402 PTKKS-------KEPLESAAATEQTPSTRRKSILKSATSRLAEGTPRRSIHLSNIVEQRVFEDDE 459
            |.:||       |...|:....:.||.:.||:|:.::.....  :||..: |::.:.:|:
Zfish    15 PRRKSSRLGSRPKSSCENKVDDKTTPLSPRKAIVGNSLGVCQ--SPRNKV-LNSPLSERL----- 71

  Fly   460 IISTPKRGRSKKTVQDNDEDY------SPKKSVQKTPTRTRRS---STTTKTATTPSKGITTATA 515
                |...| |:|..:|..:.      ||.|. :..|..:.|.   :..|...::|.:.|.::..
Zfish    72 ----PLSPR-KRTGDENGCNLPASMLGSPPKQ-RCAPLCSPRKLSFNENTPVLSSPPRPILSSHK 130

  Fly   516 TPMTPSQKMKKIRAGELS-PSMQQRTD--------LPAKDSSKSELQLAREQLHVSVVPKSLPCR 571
            .|::|..:....|..|.| .::..||:        .|.|   ||..|..::.|| :.||:.|..|
Zfish   131 VPLSPISRPSPTRLNETSCTNIIPRTEGKSPVMRLFPMK---KSGFQSVKQALH-TAVPERLLSR 191

  Fly   572 EREFENIYAFLEGKIQDQCGGCMYVSGVPGTGKTATVTGVIRTLQRMAKQNELPAFEYLEINGMR 636
            |.|...|.:||:..:..:....:|:||.|||||||.:..|::..:.:.|     ..:.:.||.|.
Zfish   192 EAERAAIVSFLQNHVVAEKPSSLYISGAPGTGKTACLNCVLQEQKALLK-----GIQTVVINCMN 251

  Fly   637 LTEPRQAYVQIYKQLTGKTVSWEQAHALLEKRFTTPAPRRVTTVLLVDELDILCNRRQDVVYNLL 701
            |......:..:.:||   .|....:.|.|||..|:..|   |.:|::||:|.|.::.|:|:|.:.
Zfish   252 LRSSHAIFPLLGEQL---EVPKGNSQARLEKYLTSSGP---TVLLVLDEMDQLDSKSQEVLYTIF 310

  Fly   702 DWPTKSAAKLVVVTIANTMDLPERL---LMGKVTSRLGLTRLTFQPYSHKQLQEIVTARL---GG 760
            :||....:::.::.|||.:||.:|:   |..|...|..|  |.|.||||::|..||..||   .|
Zfish   311 EWPYLPKSRVCLIGIANALDLTDRILPRLQAKPHCRPKL--LNFPPYSHEELNAIVQDRLTQVSG 373

  Fly   761 SETFKGEAVQLVARKVAAVSGDARRALDICRRATEIAD-----------TAAVKC--VTMLHVQQ 812
            .......|||..||||:|||||||:||||||||.||.:           ||:.|.  |::..|.:
Zfish   374 EGVLDAAAVQFCARKVSAVSGDARKALDICRRAVEIVEAGDRSKMASEPTASSKVSRVSVPQVAR 438

  Fly   813 ALAEMIAS--AKVQAIRNCSRMEQIFLQAIAAEVTRTGVEETTFMG----VYQQV--ETIAAFMG 869
            .|:|:...  |..........::|..|......:.|.|..:...:|    ||.::  :.....:|
Zfish   439 VLSEVYGDRMASSSGDGESFPLQQKLLVCCLLLIIRNGKSKEIQLGKLCEVYSKLCKQRQVGGVG 503

  Fly   870 VTFPPPGRALRLCSKLGAERLIISEHSRNDLFQKILLNVSADDIHYALR 918
            .|     ..|.|||.|.:..::..:.:::....||.|.:...|:.:||:
Zfish   504 QT-----ECLSLCSLLESRGILTLKKAKDARLTKISLKIEERDVEHALK 547

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Orc1	NP_477303.1	BAH_Orc1p_animal	44..185	CDD:240070
		AAA	591..741	CDD:214640	46/152 (30%)
		AAA	594..739	CDD:278434	46/147 (31%)
		Cdc6_C	837..917	CDD:215013	17/85 (20%)
cdc6	NP_001120805.1	CDC6	184..548	CDD:224391	119/382 (31%)
		AAA_16	187..323	CDD:289934	43/146 (29%)
		Cdc6_C	474..546	CDD:215013	16/76 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1474
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D427050at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100406
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R177
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.750