Protein Alignment Orc1 and orc1

DIOPT Version :10

• Sequence 1: NP_477303.1
• Gene: Orc1 / 35686
• FlyBaseID: FBgn0286788
• Length: 924
• Species: Drosophila melanogaster
• Sequence 2: NP_596060.1
• Gene: orc1 / 2540470
• PomBaseID: SPBC29A10.15
• Length: 707
• Species: Schizosaccharomyces pombe
• Alignment Length: 568
• Identity: 208/568 - (36%)
• Similarity: 297/568 - (52%)
• Gaps: 87/568 - (15%)

  Fly   390 RLGVANGDIYHTPTKKSKEPLE--------------SAAATEQTPSTRRKSILKSATSRLAEGTP 440
            |.||      |....|..|||:              .....|....|::||     .|| ..|.|
pombe   179 RRGV------HLKVNKYTEPLDWSYYAHNLERIEDLLVEMEENLRPTKKKS-----GSR-GRGRP 231

  Fly   441 RRSIHLSNIVEQRVFEDDEIISTPKRGRSKKTVQDNDEDYSPKKSVQ-KTPTRTRRSS--TTTKT 502
            |: ..|.|:      |..|..|..........:||:.|......::| :||.|..:.|  .::..
pombe   232 RK-YPLPNV------ESKESSSKVNSKDENFDLQDDSESSEDNLTIQPQTPRRRHKRSRHNSSNL 289

  Fly   503 ATTPSKGITTATATPMTPSQKMKKIRAGELSPSMQQRTDLPAKDSSKSELQ-----LAREQLHVS 562
            |:||.                    |.|...|  .|.|.||.:..|..|.|     .||..|||:
pombe   290 ASTPK--------------------RNGYKQP--LQITPLPIRMLSLEEFQGSPHRKARAMLHVA 332

  Fly   563 VVPKSLPCREREFENIYAFLEGKIQDQCGGCMYVSGVPGTGKTATVTGVIRTLQRMAKQNELPAF 627
            .||.:|.||:.||..|::.||..|:::.|.|:|:||.|||||||||..||..||.::::.:||.|
pombe   333 SVPSTLQCRDNEFSTIFSNLESAIEEETGACLYISGTPGTGKTATVHEVIWNLQELSREGQLPEF 397

  Fly   628 EYLEINGMRLTEPRQAYVQIYKQLTGKTVSWEQAHALLEKRFTTPAPRRVTTVLLVDELDILCNR 692
            .:.||||||:|...|||..:::.|||:.|:...|..||:.|||..:|.|.:.|:|:||||.|...
pombe   398 SFCEINGMRVTSANQAYSILWESLTGERVTPIHAMDLLDNRFTHASPNRSSCVVLMDELDQLVTH 462

  Fly   693 RQDVVYNLLDWPTKSAAKLVVVTIANTMDLPERLLMGKVTSRLGLTRLTFQPYSHKQLQEIVTAR 757
            .|.|:||..:||:...::|:||.:|||||||||:|..:::|||||:|:.|:||:|.||:.|:.||
pombe   463 NQKVLYNFFNWPSLPHSRLIVVAVANTMDLPERILSNRISSRLGLSRVPFEPYTHTQLEIIIAAR 527

  Fly   758 LGG---SETFKGEAVQLVARKVAAVSGDARRALDICRRATEIADTAAVKCVTMLHVQQALAEMIA 819
            |..   .:.|..:|::..|||||||||||||||||||||:|:|:....| ||...:.||::||.|
pombe   528 LEAVRDDDVFSSDAIRFAARKVAAVSGDARRALDICRRASELAENKNGK-VTPGLIHQAISEMTA 591

  Fly   820 SAKVQAIRNCSRMEQIFLQAIAAEVTRTGVEETTFMGVYQQVETIAAFMGVTFPPPGRA------ 878
            |...:.:||.|.|:::||.||...:.|:|..|:.   ||:.:|.....:.|...|...|
pombe   592 SPLQKVLRNLSFMQKVFLCAIVNRMRRSGFAESY---VYEVLEEAERLLRVMTTPDAEAKFGELI 653

  Fly   879 LR------LCSKLGAERLIISEH--SRNDLFQKILLNVSADDIHYALR 918
            ||      :.|.|....::..|:  |||   .::.|.::.|:|..|.|
pombe   654 LRRPEFGYVLSSLSENGVLYLENKSSRN---ARVRLAIADDEIKLAFR 698

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Orc1	NP_477303.1	BAH_Orc1p_animal	44..185	CDD:240070
		PTZ00112	<559..795	CDD:240274	122/238 (51%)
		Cdc6_C	837..917	CDD:215013	23/93 (25%)
orc1	NP_596060.1	BAH_Orc1p_like	34..193	CDD:240066	6/19 (32%)
		PTZ00112	<54..669	CDD:240274	199/534 (37%)