DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment PIG-G and AT2G22530

DIOPT Version :9

Sequence 1:	NP_610292.2	Gene:	PIG-G / 35685	FlyBaseID:	FBgn0033187	Length:	927	Species:	Drosophila melanogaster
Sequence 2:	NP_179839.5	Gene:	AT2G22530 / 816786	AraportID:	AT2G22530	Length:	958	Species:	Arabidopsis thaliana

Alignment Length:	1039	Identity:	282/1039 - (27%)
Similarity:	429/1039 - (41%)	Gaps:	258/1039 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 VYTIGMLTAFLCGAVLFLIGFFPA-----------SY-------SVAEKESTVPEGRPTALLGME 55
            ::|:..:...:.|..:|:.||||.           ||       |:...||.:.......||..|
plant    13 IFTVAGILLQIIGLSIFVFGFFPVKPTLSGVSGSESYRDPFCDSSLISNESELHHPEKLRLLYQE 77

  Fly    56 LTPPPPAYDSFVLLLVDALRDDF--------PDAT---SMPVAYSRAC--EKLKLHVDI--PTVT 105
            |:.....||..:|:::|.|..:|        |:..   |||...|...  :.:..|...  ||||
plant    78 LSGISSKYDRLILMVIDGLPAEFVLGKDGKPPEKVLKESMPYTQSLLANGDAIGYHAKAAPPTVT 142

  Fly   106 MPRLKSITTGTLSNFIDIALNVGHTEQMQDSFLHRLKQQNRVVSFAGDHTWVKLFPSEFTRQVEN 170
            |||||::.:|.:..|:|:|.|......:.|:.|.:..:....:...||.||:||||..|.|
plant   143 MPRLKAMVSGAIGGFLDVAFNFNTQALLDDNILGQFFRIGWKMVMLGDETWLKLFPGLFMR---- 203

  Fly   171 HD---SFYVNDFYEGDRNVTKTLETELERSDWSLLILHYLGLDHIGHVEGNASPRVPLKLKEMDE 232
            ||   ||:|.|..:.||||::.|..||...||:|||||||||||:||..|..||.:|.||||||:
plant   204 HDGVSSFFVKDTVQVDRNVSRHLPDELNSDDWNLLILHYLGLDHVGHTGGRNSPLMPAKLKEMDD 268

  Fly   233 VV-----KKILDHK-SFPNVLLMLTGDHGMADGGGHGGNTPAET-LVPLYLYYN-NCSKTPSASK 289
            :|     :.::|.. .....||::..||||.:.|.|||::..|| .:.|::..| |.|...||:.
plant   269 IVRTMHLRAMMDRSHDQGQTLLIIVSDHGMTENGNHGGSSYEETDSLMLFIGLNSNISDYASATN 333

  Fly   290 RYN-QIDLAPTLSVLLSVEIPTLSIGCLIPEMLQSLSLEHQLYAYFYNAHHLLNKARVKFGHEIV 353
            ... |:||||||::|..|.||..::|.|:|..|.||....||.|...|
plant   334 NVAFQVDLAPTLALLFGVPIPKNNVGVLVPGTLCSLRDFEQLRALELN----------------- 381

  Fly   354 HRSDYYTWYQNATLLHKKLLRPLREGDGGGASQVYYQNAKLNYMRVAREISDLLSESLVKFDYGF 418
                  :|         :|||.:
plant   382 ------SW---------QLLRLM------------------------------------------ 389

  Fly   419 IAVGLALTTSTSLHIVISVLYLDLT-EQLQLD-----GLKVGQL-------------W---LSVI 461
                ||...|:|...|....:||.| |.|.||     |.|..||             |   .|..
plant   390 ----LAQIQSSSFPRVSCNCFLDGTCEGLDLDISECSGDKEKQLICLFRNAAALHGIWKSKKSTE 450

  Fly   462 AAVVLNYTSHALDIIMT----------SSTLYSILLLVPISI-AVYLTIDVAQALLKIALPPLY- 514
            ::..:...|.|||...|          |.|....:||:.:.: |:.|:..:...:.......:|
plant   451 SSSTMEDFSRALDAYNTFLKTASEWLASKTTEKPVLLLGLGVSAMLLSCFICGTVFLSLFKEVYH 515

  Fly   515 ---TRRLKISIPLPLP---LLACYAIRTLTLGSSSFIEFEYNTWYYLGNTLILLTAFRTLR-WRI 572
               .|...:|..|.|.   :.|...|..:::||||.:|.|:..|:::.:|..||..|:|.: ::|
plant   516 EPKDRVCSLSNLLNLEEVFIFALLLILVISMGSSSMVEEEHYIWHFMVSTFHLLLLFKTAKSFKI 580

  Fly   573 TK-TNV-----------------ELNGRHLYTIASTCL----------------W-QMRKVLVV- 601
            :| .|:                 .|.|.|...:..|.|                | |:..:::|
plant   581 SKGMNILRDFKFGSIFSLLISGRLLRGWHQGGVNWTYLPDISKWLVQGGSGYVKWIQLISIILVI 645

  Fly   602 -LMLLTLMRYIHRLQAIRSTVVIFSMLLLWARLH---RHSQLPQSLASGAALFMVYCFRGLNGQV 662
             |.|.||.|.....:.:|.....||.......||   ...:|.....:...:.::|....:
plant   646 GLGLYTLFRTGSNRKGVRILAFGFSTCGFLVLLHVGRYQDELSTGFGATVTVKVIYYLLSI---- 706

  Fly   663 LFFDVPSHMAAKLMVPTLVIFWCCLALVLMLGYRAALPQAHSFGKVPPTGALLQLL-QTNLTSSL 726
                  |.:.|.|::|     |            :||.:..||  :...|..|.|: ...:....
plant   707 ------SSIGASLVLP-----W------------SALNKDKSF--LAEVGDCLYLIGSAYILCWC 746

  Fly   727 LLAALLQRVHNILLLPVLLVALQQTYKLCDVYGTSARKFSVRLVHVYKIIMTIFLARMFFFYQGN 791
            ||..|||:..|  ..|:||:.||....||    .|:..|.|.  ...:|....::.....|..||
plant   747 LLQQLLQQPIN--SGPILLLLLQILAILC----LSSSDFQVN--EWVEITALYYMGMAGHFALGN 803

  Fly   792 SNSLSTIDLTPGYIGQTNYNPSIVAIFVTLNTYSADIHAFLYLVVHTLRSDLR--SVGIMQLHPP 854
            ||:|:|||:...:||.::::..:..|.:.:.||::.:...|.||:: :.::||  |...:..|..
plant   804 SNTLATIDVAGAFIGISSHSTILSGILMFMITYASPMLFLLSLVMY-IGANLRNHSNSTISTHRE 867

  Fly   855 YSIA-------ADSLIAPLYAALIMLPAAFYLCLLVGFRYHLFIYSVFSPKVLYDCYTVLVFYL 911
            .|:.       ....:.||....|:|.|  |..:|:..|.|||::||||||.||.|.|.|..|:
plant   868 TSLGQILKLKLGFPCLVPLCINSILLTA--YTVVLLLMRNHLFVWSVFSPKYLYVCATTLCTYI 929

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PIG-G	NP_610292.2	GPI_EPT_2	60..317	CDD:293748	108/283 (38%)
AT2G22530	NP_179839.5	GPI_EPT_2	82..362	CDD:293748	108/283 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	125	1.000	Domainoid score	I1799
eggNOG	1	0.900	-	-		E1_COG1524
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	271	1.000	Inparanoid score	I917
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D848878at2759
OrthoFinder	1	1.000	-	-		FOG0005039
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_104308
Panther	1	1.100	-	-	LDO	PTHR23072
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3564
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	12	11.830