DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PIG-G and enpp7.1

DIOPT Version :9

Sequence 1:	NP_610292.2	Gene:	PIG-G / 35685	FlyBaseID:	FBgn0033187	Length:	927	Species:	Drosophila melanogaster
Sequence 2:	NP_001243734.1	Gene:	enpp7.1 / 557756	ZFINID:	ZDB-GENE-040724-13	Length:	485	Species:	Danio rerio

Alignment Length:	538	Identity:	97/538 - (18%)
Similarity:	172/538 - (31%)	Gaps:	172/538 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 AVLFLIGFFPASYSVAEKESTVPEGRPTALLGMELTPPPPAYDSFVLLLVDALRDDFPDATSMPV 86
            |:..|:..||||.|...:      |..|.           ..:..:|:..|..|.|:......|.
Zfish     4 ALSILLLAFPASLSAPTR------GHCTT-----------GKNKLLLISFDGFRWDYDRDVDTPN 51

  Fly    87 AYSRACEKLKLHVDIP---TVTMPRLKSITTGT-LSNFIDIALNVGHTEQMQDSFLHRLKQQNRV 147
            ....|.:.:|.....|   |:|.|...::.:|. :.|...|..|..:|...:       |:|..:
Zfish    52 LDKMAVDGVKAAYVTPPFLTITSPTHFTLLSGRYIENHGVIHNNWFNTTTQE-------KKQYYM 109

  Fly   148 VSFAGDH-------TWVKL-----------FPSEFTRQVENHDSFYVND----FYEGD------R 184
            ..|..|:       .|:..           ||.  |.....::...|.:    ||:..      .
Zfish   110 TQFVNDYWDNGSLPIWITAQRQGLKTGSLHFPG--TAAKYQNEKIKVGEVEPRFYDHTNETLWME 172

  Fly   185 NVTKTLETELERSDWSLLILHYLGLDHIGHVEGNASPRVPLKLKEMDEVVKKILD----HKSFPN 245
            .|.|.::...:..|...:.|::...|..||..|..||.....:|::|..|..|.:    |....:
Zfish   173 KVDKVMKDWFKDQDLDFVTLYFGDPDSTGHKYGPDSPERREAVKKVDRTVGYIRETAKKHGLSDH 237

  Fly   246 VLLMLTGDHGMA-----------------------------DGGGHGGNTPAETLVPLYLYYNNC 281
            :.:::|.||||:                             |.|..|...|.|.::
Zfish   238 LNIIITADHGMSTVFKGDQVKEIVLTDIPGFSLKDLKFHMVDYGPFGMLLPKEGML--------- 293

  Fly   282 SKTPSASKRYNQIDLA-PTLSVLLSVEIPTLSIGCLIPEMLQSLSLEHQLYA---YFYNAHHLL- 341
                  .|.||.:... |.|:|....::|........|.:|..:     |||   |..|..::.
Zfish   294 ------DKVYNALKGGHPHLNVYKKEDMPARLHYSKHPRLLPII-----LYADPGYVINGFYVFQ 347

  Fly   342 -NKARVKFGHEIVHRSDYY-----TWYQN------------ATLLHKKLLRP-LREGD------- 380
             ||....:.:|::....::     .:::|            ..:.|...:|| :.:|.
Zfish   348 NNKGEHGYDNEVMDMKPFFRAVGPDFHRNLLVGPFETVNVYPLMCHLIGIRPEINDGSLVNTRHM 412

  Fly   381 ----------GGGASQVYYQNAKLNYMRVAREISDLLSESLVKFDYGFIAVGLALTTSTSLH--- 432
                      ||...:...:|..:....||                ||:.:...:.||..:|
Zfish   413 LKSNGETCGYGGDGPESSLRNVFIGLGAVA----------------GFLLLAFVVITSYKVHKRR 461

  Fly   433 -IVISVLYLDLTEQLQLD 449
             :..|...:|..:|::.|
Zfish   462 KVNQSPKVIDDEDQMKAD 479

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PIG-G	NP_610292.2	GPI_EPT_2	60..317	CDD:293748	59/322 (18%)
enpp7.1	NP_001243734.1	Enpp	29..396	CDD:293742	71/395 (18%)
enpp7.1	NP_001243734.1	Phosphodiest	31..356	CDD:279931	68/353 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1524
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900