Protein Alignment PIG-G and Pigg

DIOPT Version :10

• Sequence 1: NP_610292.2
• Gene: PIG-G / 35685
• FlyBaseID: FBgn0033187
• Length: 927
• Species: Drosophila melanogaster
• Sequence 2: NP_001297618.1
• Gene: Pigg / 433931
• MGIID: 3576484
• Length: 983
• Species: Mus musculus
• Alignment Length: 1060
• Identity: 291/1060 - (27%)
• Similarity: 455/1060 - (42%)
• Gaps: 265/1060 - (25%)

  Fly    21 GAVLFLIGFFPA---SYSVAEKESTVPEGRPTALLGMELTP-PPPAYDSFVLLLVDALRDDFPDA 81
            |..:|:.|||||   |.:..|.::..|...|.|.:....|. |||.:...|::|:|||||||...
Mouse    19 GVAIFIRGFFPAPVRSSARPEHDAETPAPEPVAGVRSNWTKLPPPLFSKVVIVLIDALRDDFVFG 83

  Fly    82 TS----MPVAYSRACEKLKLHVDI-----PTVTMPRLKSITTGTLSNFIDIALNVGHTEQMQDSF 137
            :.    ||.. :...||...|..:     |||||||:|::.||:|..|:|:..|:.....::|:.
Mouse    84 SKGVKYMPYT-TYLVEKGASHSFVAEAKPPTVTMPRIKALMTGSLPGFVDVIRNLNSPVLLEDNV 147

  Fly   138 LHRLKQQNRVVSFAGDHTWVKLFPSEFTRQVENHDSFYVNDFYEGDRNVTKTLETELERSDWSLL 202
            |.:.|...:.:.|.||.|||||||..|. :.:...||:|:|:.|.|:|||:.|:..|:|.||.:|
Mouse   148 LRQAKAAGKRIIFYGDETWVKLFPKHFV-EYDGTTSFFVSDYIEVDKNVTRHLDKVLKRGDWDVL 211

  Fly   203 ILHYLGLDHIGHVEGNASPRVPLKLKEMDEVVKKI------LDHKSFPNVLLMLTGDHGMADGGG 261
            ||||||||||||:.|..||.:..||.|||.|:.||      .|.::....||:|.|||||::.|.
Mouse   212 ILHYLGLDHIGHISGPNSPLIGHKLSEMDSVLMKIHTSLLSKDRETLLPSLLVLCGDHGMSETGS 276

  Fly   262 HGGNTPAETLVPLYLYYNNCSKTPS---ASKRYNQIDLAPTLSVLLSVEIPTLSIGCLIPEMLQS 323
            ||.::..|...||.|..:...:.|.   ..|...|.|||.||::.|.:.||..|:|.|:..:::.
Mouse   277 HGASSTEEVSTPLLLISSAFERKPGDIRHPKHVQQTDLAATLAIGLGLPIPKDSVGSLLFPVIEG 341

  Fly   324 LSLEHQLYAYFYNAHHLLNKARVKFGHEIVHRSDYYTWYQNATLLHKKLLR---PLREGDGG--- 382
            ..:..||.....|                             ||...|||:   |..|.|.|
Mouse   342 KPMREQLRFLHLN-----------------------------TLQLSKLLQENVPSYEKDPGFEQ 377

  Fly   383 --GASQVYYQNAKL-------------------NYMRVAREISDLLSESLVKFDYGFIAVG---- 422
              .|.:::....||                   :|:...:.:|..||..:.::|...:|||
Mouse   378 FKMAEKLHGNWVKLHLEENHSDILLGLGTKVLRHYLGALKTLSLSLSTQVAQYDMYSMAVGTLIV 442

  Fly   423 ---LALTTSTSLHIVISVLYLDLTEQLQLDGLKVGQLWLSVIAAVVLNYTSHALDIIMTSSTLY- 483
               |||...::.|::.....||:.....:..|....::| |::|:      |.|....:.|:.|
Mouse   443 LEVLALFLLSTPHVLCRKAELDVPLLSPVFSLLFYLVFL-VLSAI------HVLVCTSSESSCYL 500

  Fly   484 ---------SILLLVP------ISIAVYLTIDVAQALLKIALPPLYTRRLKISIPLPLPLLACYA 533
                     :::|||.      :|..:.:.||  ..|||.......:...::::.|.|..:.
Mouse   501 CSLSWLAVGAVMLLVSALFCAILSALIRMVID--STLLKKNAADASSGWSEVNLLLLLGTVG--- 560

  Fly   534 IRTLTLGSSSFIEFEYNTWYYLGNTLILLTAFRTLRWRI-------------------------- 572
             ..|:||:|||:|.|:.|||:|.|||.|..:..|.|...
Mouse   561 -HVLSLGASSFVEEEHQTWYFLINTLCLALSQETCRSYFLGDECEPQRHSHVEQQCVNLLACPLQ 624

  Fly   573 --TKTNVELNGR-----HLYTIASTCLW--QMRKVLVVLMLLTLMRYI----------------- 611
              |..|...:|.     .|.....:|.|  .:....:||:...|:|.:
Mouse   625 DSTSYNTPESGTAGKRVSLLEAQGSCKWWTVLASPWLVLLCCRLLRSLNQTGVQGAHRPDFSHWL 689

  Fly   612 ----HRLQ----AIRSTVVIFSMLLLWARLHRHSQLPQSLASGAALFMVYCFRGLNGQVLF-FDV 667
                |::|    |..|.||||.:      :.|...|...:|....|..|:|:|...|.|.| :..
Mouse   690 TSSDHKVQLSGLAALSLVVIFML------VQRRCSLVSKVALALGLLGVFCYRAAIGIVQFPWQS 748

  Fly   668 PSHMAAKLMVPTLVIFWCCLALVLMLGYRAALPQAHSFGKVPPTGALLQLLQTNLTSS------- 725
            .:...:|.::....::...|. :|..|.:..|.              .|::.|:..:.
Mouse   749 DNKGISKGIIEARFVYVFVLG-ILFTGTKDLLK--------------AQVIATDFKTKTVGLWEM 798

  Fly   726 ----LLLAALLQRVHNILLLPVLLVALQQTYKLCDVYGTSARKFSVRLVHVYK---------IIM 777
                :||||||.|.||   ||||..:|        :..|...||      ::|         .:|
Mouse   799 HSGLVLLAALLLRPHN---LPVLAFSL--------LIQTVMTKF------IWKPLRHDAAEITVM 846

  Fly   778 TIFLARMFFFYQGNSNSLSTIDLTPGYIGQTNYNPSIVAIFVTL-NTYSADIHAFLYLVVHTLRS 841
            ..:..:.||::|||||:::|||::.|::|...| ..:.|.|:|: .||...:
Mouse   847 HYWFGQAFFYFQGNSNNIATIDISAGFVGLDTY-MEVPATFLTVFGTYVGPV------------- 897

  Fly   842 DLRSVGIMQLHPPYSIAADSLIAPL------YAALIMLPAAFYLCLLVGFRYHLFIYSVFSPKVL 900
                  :...|..|.::::...:.|      ||.:..:|.|.|:.|:...||||||:||||||:|
Mouse   898 ------LWASHLVYFLSSEGNNSALSRSCFCYALICSVPVATYIVLVTSLRYHLFIWSVFSPKLL 956

  Fly   901 YDCYTVLV---FYLVFLVTS 917
            |:...:|:   ...||..|:
Mouse   957 YEGMHLLITAAICAVFTATN 976

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PIG-G	NP_610292.2	GPI_EPT_2	60..317	CDD:293748	111/274 (41%)
		PIGO_PIGG	<776..901	CDD:437148	40/131 (31%)
Pigg	NP_001297618.1	GPI_EPT_2	62..335	CDD:293748	111/274 (41%)
		PIGO_PIGG	<811..965	CDD:437148	55/190 (29%)