Protein Alignment PIG-G and pigg-1

DIOPT Version :9

• Sequence 1: NP_610292.2
• Gene: PIG-G / 35685
• FlyBaseID: FBgn0033187
• Length: 927
• Species: Drosophila melanogaster
• Sequence 2: NP_001022123.1
• Gene: pigg-1 / 174377
• WormBaseID: WBGene00009204
• Length: 745
• Species: Caenorhabditis elegans
• Alignment Length: 959
• Identity: 235/959 - (24%)
• Similarity: 377/959 - (39%)
• Gaps: 331/959 - (34%)

  Fly    50 ALLGMELTPPPPAYD--------------SFVLLLVDALRDDFPDATSMPVAYS------RACEK 94
            :.:.:::||.||..:              ..|.:::||.|..|..::..|::::      ::.:.
 Worm    25 SFVALDITPTPPTEEFGFKDGNQESSSSPRLVFMVIDAFRLSFLTSSKSPMSFTKSEITKKSAKL 89

  Fly    95 LKLHVDIPTVTMPRLKSITTGTLSNFIDIALNVGHTEQMQDSFLHRLKQQNRVVSFAGDHTWVKL 159
            ...:..:||||:||:.:..||||.:|..:..|:...|....:::.|:::..:.|.|.||.||::|
 Worm    90 FDAYARMPTVTLPRITAYLTGTLPSFGTVLTNLATAEMKTANWISRIQKIGKKVHFFGDDTWIRL 154

  Fly   160 FPSEFTRQVENHDSFYVNDFYEGDRNVTKTLETELERSD--WSLLILHYLGLDHIGHVEGNASPR 222
            .|..| .:.|...||:|:|:.:.|.|||:.|:|||..::  |..|||||||||||||..|.:|.:
 Worm   155 LPRSF-EKFEGVTSFFVSDYTDVDNNVTRHLDTELSNTNHSWDALILHYLGLDHIGHSLGGSSSK 218

  Fly   223 VPLKLKEMDEVVKKI---------LDHKSFPNVLLMLTGDHGMADGGGHGGNTPAETLVPLYLY- 277
            :|.||||||:|:.:|         :|.:|:    |::.|||||...|.|||.:|.||.||:.::
 Worm   219 IPEKLKEMDDVIGRIHKYLKSSTSVDQESY----LIVCGDHGMTAAGSHGGASPDETRVPVVIWK 279

  Fly   278 ---------YNNCSKTPSASKRYNQIDLAPTLSVLLSVEIPTLSIGCLIPEMLQSLSLEHQLYAY 333
                     |.|...:.....|..|||::.|:..:.::.||..|.|.             .|..|
 Worm   280 FGREEGNKNYGNQDDSLKQPPRIEQIDVSSTIFDVFNMPIPIESYGI-------------SLINY 331

  Fly   334 FYNAHHLLNKARVKFGHEIVHRSDYYTWYQNATLLHKKLLRPLREGDGGGASQVYYQNAKLNYMR 398
            |                     ||                          ..:.|::.....:.|
 Worm   332 F---------------------SD--------------------------DEEEYFEKQHNQFRR 349

  Fly   399 VAR----EISDLLSESLVKFDYG-----------FIAVGLALTTST------SLHIVISVLYLDL 442
            :.:    .|||:..|:.   ||.           |:.|...|..|.      ||.:.:.:|.:.|
 Worm   350 IVQAKHLAISDICDENC---DYSDKFIKSALKKWFLTVQSELIGSASEVPNKSLGVCVFLLLVAL 411

  Fly   443 TEQLQLDGLKVGQLWLSVIAAVVLNYTSHALDIIMTSSTLYSILLLVPISIAVYLTIDVAQALLK 507
            |       |.:| ||                ::.::.|..:..|:
 Worm   412 T-------LSMG-LW----------------NLHLSKSDFFIFLI-------------------- 432

  Fly   508 IALPPLYTRRLKISIPLPLPLLACYAIRTLTLGSSSFIEFEYNTWYYLGNTLILLTAFRTLRWRI 572
                                        .:|..:||.||.|:..|||||:|::.:.|.|..:
 Worm   433 ----------------------------NITYFASSLIEEEHEIWYYLGSTVVAIRALRNFK--- 466

  Fly   573 TKTNVELNGRHLYTIASTCLWQMRKVLVVLMLLTLMRYIHRL-----QAIRSTVVIFSMLLLWAR 632
                               :|...:|..:..|    .::||:     |:.|...::.|.|
 Worm   467 -------------------IWNKTEVKSIFFL----AFLHRIACSYTQSTRRRWIMDSSL----- 503

  Fly   633 LHRHSQLPQSLASGAALFMVYCFRGLNGQVLFFDVPSHMAAKL-MVPTLVIFWCCLALVLMLGYR 696
                  ||.|:.|....|.                |:::...| ..|.:||..|  :|..|.||:
 Worm   504 ------LPPSIFSDTLDFQ----------------PNNLNTILNEYPIIVILTC--SLFWMYGYK 544

  Fly   697 AA-----LPQAHSFGKVPPTGALLQLLQTN----------------LTSSLLLAALLQRVHNILL 740
            .:     ||....|.:      |.:|.|.|                .|.|:|...
 Worm   545 QSKFHIILPMVSHFLR------LFELTQFNEVLMHFIRLSILPISYSTGSVLAGC---------- 593

  Fly   741 LPVLL--VALQQTYKLCDVY--GTSARKFSVRLVHVYKIIMTIFLARMFFFYQGNSNSLSTIDLT 801
            ||:||  |.:.|...|..:|  |....|.::..|....:.|:      .|||.||||||||:.||
 Worm   594 LPLLLAIVPVSQILLLLVIYNMGKLFSKLNLGSVEFVTLCMS------SFFYTGNSNSLSTLSLT 652

  Fly   802 PGYIGQTNYNPSIVAIFVTLNTYSADIHAFLYLVVHTLRSDLRSVGIMQLHPPYSIAADSLIAPL 866
            ..|:|.::|.|.:|.:.:.|.|:|..|   |:|......|                 ..||:..|
 Worm   653 SAYVGLSSYQPILVGLQLMLYTFSGPI---LFLCGCNASS-----------------CTSLLNHL 697

  Fly   867 YAALIMLPAAFYLCLLVGFRYHLFIYSVFSPKVLYDCYTVLVFYLVFLV 915
            ::..|.......:||.: |:.||||:||:||||:||...|:.|.|:.|:
 Worm   698 FSYRISSMCTSLICLYI-FQNHLFIWSVYSPKVVYDMAHVIFFGLIGLL 745

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PIG-G	NP_610292.2	GPI_EPT_2	60..317	CDD:293748	97/297 (33%)
pigg-1	NP_001022123.1	GPI_EPT_2	54..328	CDD:293748	95/291 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160167586
Domainoid	1	1.000	121	1.000	Domainoid score	I3534
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	257	1.000	Inparanoid score	I1943
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28704
OrthoDB	1	1.010	-	-		D313125at33208
OrthoFinder	1	1.000	-	-		FOG0005039
OrthoInspector	1	1.000	-	-		oto18692
orthoMCL	1	0.900	-	-		OOG6_104308
Panther	1	1.100	-	-	LDO	PTHR23072
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R518
SonicParanoid	1	1.000	-	-		X3564
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	14	13.940