Protein Alignment PIG-G and PIG-N

DIOPT Version :10

• Sequence 1: NP_610292.2
• Gene: PIG-G / 35685
• FlyBaseID: FBgn0033187
• Length: 927
• Species: Drosophila melanogaster
• Sequence 2: XP_061501737.1
• Gene: PIG-N / 1273897
• VectorBaseID: AGAMI1_005154
• Length: 920
• Species: Anopheles gambiae
• Alignment Length: 930
• Identity: 194/930 - (20%)
• Similarity: 307/930 - (33%)
• Gaps: 300/930 - (32%)

  Fly    23 VLFLIGFFPASYSVAEKESTVPEGRPTALLGMELTPPPPAYDSFVLLLVDALRDDFPDATSMPVA 87
            ||||:..|...:     :|.:.:|.|.   |.|...||.  |..||.:.|.||
Mosquito    12 VLFLLSIFYIHF-----QSPILKGLPD---GAEHDHPPA--DRLVLFVGDGLR------------ 54

  Fly    88 YSRACEKLKLH----------------------VDIPTVTMPRLKSITTGTLSNFIDIALNVGHT 130
                .|....|                      ..:||.:.|...::..|...:  ..|:..|..
Mosquito    55 ----AESFLRHDLNRTHFLRNTLLREGVFGISNTRVPTESRPGHAALLAGVYED--PSAVFRGWK 113

  Fly   131 EQMQ--DSFLHRLKQQNRVVSFA-GDHTWVKLFPSEFT-------RQVENHDSF----------- 174
            |...  ||.|:|..     ||:. |....|.:|....|       ....|.:||
Mosquito   114 ENPVEFDSVLNRSS-----VSYCWGSPDIVHMFSRGATPGRVHVAAYDSNDESFAQSANTSLLDI 173

  Fly   175 ----YVNDFYEGDRNVTKTLETELERSDWSLLILHYLGLDHIGHVEGNASPRVPLKLKEMDEVVK 235
                .|.:|..|::.....:.::.:    .:|.||.||||..|||....|......|..:|:.::
Mosquito   174 WVFDRVREFLAGEQQTKGGVLSQKK----VVLFLHLLGLDTAGHVHKPYSELFTENLITVDKGIE 234

  Fly   236 KIL-----DHKSFPNVLLMLTGDHGMADGGGHGGNTPAETLVPLYLY---------------YNN 280
            .|:     ..|:......:.|.||||.|.|.||...|.||..|...:               |:|
Mosquito   235 SIVRLIERATKNDGRTAYIFTSDHGMTDQGSHGAGHPHETETPFLAWGAGFKHWKEAIPASDYSN 299

  Fly   281 CSKTPSAS---KRYNQIDLAPTLSVLLSVEIPTLSIGCLIPEMLQSLSLEHQLYAYFYNAHHLLN 342
            ..:....|   ...||.|.||.::.:|.:.:|..|:|.| |..|.::|.|:..:|...||..||
Mosquito   300 ALELDGKSIPVHHLNQADAAPLMAAVLGIAVPKNSLGKL-PRSLLNVSEEYAAWAMRNNAEQLL- 362

  Fly   343 KARVKFGHEIVHRSDYYTWYQNATLLHKKLLRPLREGDGGGASQVYYQNAKLNYMRVARE-ISDL 406
                         |.|:.|.              ||.:  |....:..|.|...::|..| :...
Mosquito   363 -------------SQYHHWQ--------------RESE--GKMLQWLVNTKQTSLKVLIEALQSE 398

  Fly   407 LSESLVKFDYGFIAVGLALTTSTSLHIVISV-------LYLDLTEQLQLDGLKVGQLWLSVIA-- 462
            ::::..:.||..:.....:...|:|:.:...       |||.||  |.:.|      ||.::|
Mosquito   399 IADADYRKDYTEVQSLTKMLIDTALNAIEYFQTYYKPHLYLALT--LTMLG------WLLLLAKE 455

  Fly   463 -------------------AVVLNYTSHALDIIMTSSTLYSILLLVPISIAVYL----------- 497
                               |||:..|....:|...:.|:..:..::|:.:..|:
Mosquito   456 TCTPTNTRIFALNRAVALTAVVVALTVTVFNIAQNTPTVVVLYFVLPVVLWGYIGAHWRQYAPLL 520

  Fly   498 ----------TIDVAQALL------KIALPPLYTRRLKISIPL--------------------PL 526
                      .|..|:||:      ::..|.|:...|.:..||                    .|
Mosquito   521 QGKAAMYSAGFIIAAEALVWAFMDRRLLAPLLWVHCLIVVKPLLDRKPSDVNNRSMVRHWIAFNL 585

  Fly   527 PLLACYAIRTLTLGSSSFIEFEYNTWYYLGNTLILLTAFRTLRWRITKTNVELNGRHLYTIASTC 591
            .|...:.:.|:...||:                :.|.......|....|.:....:|      |.
Mosquito   586 LLSGFFLLPTIGRDSSN----------------VYLLCISIFAWTAVNTMIVHRSKH------TS 628

  Fly   592 LWQMRKVLV-VLMLLTLMRYIHRLQA-------IRSTVVIFSMLLLWARLHRHSQLPQSLASGAA 648
            |.:...||| :|....|:..|..:||       .||...:||.|.|.|        |.|.::..:
Mosquito   629 LLKSIAVLVQLLQAANLLYLIFLIQASANVPQWCRSLCWVFSGLGLLA--------PYSTSTSVS 685

  Fly   649 LFMVYCFRGLNGQVLFFDVPSHMAAKLMVPTLVIFWCCLALVLMLGY-------RAALPQAHSFG 706
            ..|:..|.||:|        .:|...|....|.:...|..|.|.|..       |.||...|...
Mosquito   686 DRMLALFSGLSG--------PYMMLSLSYEPLFLLCFCYTLYLWLNVENCMRNKRIALDSFHYCS 742

  Fly   707 KVPPTGALLQLLQTNLTSSLLLAALLQRVHNILLLPVLLVALQQTYKLCDV----------YGTS 761
            .:...|: :....|.||...:|              .|||:...|..|..|          :.|:
Mosquito   743 SIQAEGS-IDFKNTRLTFGFML--------------FLLVSFFGTGNLATVSSFDTNWVRCFVTT 792

  Fly   762 ARKFSVRLVHVYKIIMTIFL 781
            ...|::..:.|:|:::.:.|
Mosquito   793 FSPFTMMALIVFKLLVPVLL 812

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PIG-G	NP_610292.2	GPI_EPT_2	60..317	CDD:293748	72/326 (22%)
		PIGO_PIGG	<776..901	CDD:437148	1/6 (17%)
PIG-N	XP_061501737.1	None