DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1602 and CG8089

DIOPT Version :9

Sequence 1:	NP_610291.2	Gene:	CG1602 / 35684	FlyBaseID:	FBgn0033186	Length:	577	Species:	Drosophila melanogaster
Sequence 2:	NP_611014.1	Gene:	CG8089 / 36679	FlyBaseID:	FBgn0033993	Length:	624	Species:	Drosophila melanogaster

Alignment Length:	458	Identity:	104/458 - (22%)
Similarity:	182/458 - (39%)	Gaps:	101/458 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   174 DYKEPKKCKEALKRMAIDLEATVSVFLNEMALKLAIKKVHMQFNTVHKRVVSGKQKPQSLAFSIY 238
            |..|.|..|..|:::|..|: |||........:||.::.|            |..:|:..|..:.
  Fly   114 DAFEEKNRKVQLEKLAAILD-TVSSGYRRSVSQLAGQEAH------------GALRPKIAALFLP 165

  Fly   239 KLCC-----------FLNASNDEEGA---TNNEKIKLDFSK---KNKLTTDLIEMYANFPQLYDS 286
            .|.|           .|....|.:..   ::|...::.:.:   ::.||:.:|....:..:|::
  Fly   166 GLRCDCYKCENLPWKKLQDVEDHQKTHRYSDNFHCQICYRRFYLQHSLTSHIIRKSTSSRELHE- 229

  Fly   287 NHKEFSNMSSRKQAYESMAAEISVPNVDINSDDIFRAIQNLRQWYYKNTKHAIYAGSTAEKFYLE 351
             :|.:..:...:::.|....|:|:..|:   |.:....::|:.::...:||.|....|:......
  Fly   230 -NKRYKRLLENQKSQEEKELELSLNKVE---DILVPVAEDLQSYFKDESKHPIQKRKTSSLSKCP 290

  Fly   352 VCRFMPAKMYKQRLVCEFCHQITSSDHVLQSHIFKAHNIGELPFKCTLCDRSFVGRCELANHIQR 416
            .|        .|.....|.||:    |:::....:.:.  ..||.|:.|:|||:.|..|..|.||
  Fly   291 SC--------AQNYGFSFSHQL----HMVKHRRERLYT--NFPFHCSFCNRSFLTRKFLRKHQQR 341

  Fly   417 VHIGKT-----HKCTHCERSFAVMSDLQLHI-RTHTGHKP-YVC--------------EHCGKAF 460
            |....|     .||.||...|.:.|.|..|: |.|...|| .:|              :.|.:|.
  Fly   342 VRTFSTLLYRPFKCPHCTWRFQLKSALDSHVLRIHERRKPCLICKLPTSRLCCSAHTSKECNRAM 406

  Fly   461 RLRSQMTLHVTAIHTKIRAFK--------------CTMCPKDFVKKVDLSDHI-KGHLNIRDKIC 510
            :          ....|:|..:              |.:|.:.|.:|..|.:|: |.|||.|:..|
  Fly   407 Q----------KYRDKMRPLREPPKGGCRKQPTPVCKICNRKFTRKFFLEEHMNKAHLNKRNFTC 461

  Fly   511 SVCGKGFTSCHALIRHRQ-IHSEVKKFVCKLCDSRFSQFVGLNTHMK-RTH--NILR--NNSQKG 569
            .:||..|.|...:..||: :|..|....|::||...........|.| ::|  |:::  .|:.|.
  Fly   462 EICGANFYSQGTMQTHRKAVHLLVHTVQCEVCDLTIKSKGNYRRHCKSQSHKDNLVKFGKNNDKT 526

  Fly   570 KDA 572
            ||:
  Fly   527 KDS 529

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1602	NP_610291.2	GT1	157..244	CDD:304916	18/80 (23%)
		MADF_DNA_bdg	273..356	CDD:287510	14/82 (17%)
		C2H2 Zn finger	367..388	CDD:275368	4/20 (20%)
		C2H2 Zn finger	397..418	CDD:275368	10/20 (50%)
		COG5048	<423..554	CDD:227381	40/162 (25%)
		C2H2 Zn finger	425..445	CDD:275368	8/20 (40%)
		zf-H2C2_2	437..460	CDD:290200	8/38 (21%)
		C2H2 Zn finger	453..470	CDD:275368	3/30 (10%)
		C2H2 Zn finger	482..502	CDD:275368	7/20 (35%)
		C2H2 Zn finger	510..530	CDD:275368	7/20 (35%)
		C2H2 Zn finger	538..559	CDD:275368	5/21 (24%)
CG8089	NP_611014.1	C2H2 Zn finger	289..309	CDD:275368	6/31 (19%)
		C2H2 Zn finger	322..343	CDD:275368	10/20 (50%)
		C2H2 Zn finger	355..376	CDD:275368	8/20 (40%)
		C2H2 Zn finger	432..453	CDD:275368	7/20 (35%)
		C2H2 Zn finger	461..486	CDD:275368	8/24 (33%)
		C2H2 Zn finger	490..506	CDD:275368	3/15 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45440009
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840