DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1602 and Zbtb16

DIOPT Version :9

Sequence 1:	NP_610291.2	Gene:	CG1602 / 35684	FlyBaseID:	FBgn0033186	Length:	577	Species:	Drosophila melanogaster
Sequence 2:	NP_001013199.1	Gene:	Zbtb16 / 353227	RGDID:	727921	Length:	673	Species:	Rattus norvegicus

Alignment Length:	315	Identity:	78/315 - (24%)
Similarity:	134/315 - (42%)	Gaps:	45/315 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   259 IKLDFSKKNKLTTDLIEMYANFPQLYDSNHKEFSNMS----SRKQAYESMAAEISVPNVDINSDD 319
            :.:|||....|          .||.: ...:.||.:.    ..|.....:..:.||..|::..::
  Rat   364 VSMDFSTYGGL----------LPQGF-IQRELFSKLGELAVGMKAESRPLGEQCSVCGVELPDNE 417

  Fly   320 IFRAIQNLRQWYYKNTKHAIYAGSTAEKFYLEVC--RFMPAKMYKQRL----------VCEFCHQ 372
               |::..|:.:           |..:.:..|:|  ||:.:...:..|          ||:.|..
  Rat   418 ---AVEQHRKLH-----------SGMKTYGCELCGKRFLDSLRLRMHLLAHSAGAKAFVCDQCGA 468

  Fly   373 ITSSDHVLQSHIFKAHNIGELPFKCTLCDRSFVGRCELANHIQRVHIG-KTHKCTHCERSFAVMS 436
            ..|.:..|::| .:.|...::...|.||.:.|..:..|..|:: ||.| :::.|:.|.|:|...:
  Rat   469 QFSKEDALETH-RQTHTGTDMAVFCLLCGKRFQAQSALQQHME-VHAGVRSYICSECNRTFPSHT 531

  Fly   437 DLQLHIRTHTGHKPYVCEHCGKAFRLRSQMTLHVTAIHTKIRAFKCTMCPKDFVKKVDLSDHIKG 501
            .|:.|:|:|||..||.||.||..||..|.:..| ..|||..:.::|..|.|.|..|..|..|.:.
  Rat   532 ALKRHLRSHTGDHPYECEFCGSCFRDESTLKSH-KRIHTGEKPYECNGCGKKFSLKHQLETHYRV 595

  Fly   502 HLNIRDKICSVCGKGFTSCHALIRHRQIHSEVKKFVCKLCDSRFSQFVGLNTHMK 556
            |...:...|.:|.:......|:|:|.:.|:....:.|.:|.........:..|||
  Rat   596 HTGEKPFECKLCHQRSRDYSAMIKHLRTHNGASPYQCTICTEYCPSLSSMQKHMK 650

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1602	NP_610291.2	GT1	157..244	CDD:304916
		MADF_DNA_bdg	273..356	CDD:287510	14/88 (16%)
		C2H2 Zn finger	367..388	CDD:275368	5/20 (25%)
		C2H2 Zn finger	397..418	CDD:275368	6/20 (30%)
		COG5048	<423..554	CDD:227381	39/130 (30%)
		C2H2 Zn finger	425..445	CDD:275368	7/19 (37%)
		zf-H2C2_2	437..460	CDD:290200	12/22 (55%)
		C2H2 Zn finger	453..470	CDD:275368	7/16 (44%)
		C2H2 Zn finger	482..502	CDD:275368	7/19 (37%)
		C2H2 Zn finger	510..530	CDD:275368	5/19 (26%)
		C2H2 Zn finger	538..559	CDD:275368	5/19 (26%)
Zbtb16	NP_001013199.1	BTB	25..106	CDD:279045
		BTB	35..>106	CDD:197585
		C2H2 Zn finger	406..426	CDD:275368	5/22 (23%)
		C2H2 Zn finger	434..454	CDD:275368	5/19 (26%)
		COG5048	<448..622	CDD:227381	53/176 (30%)
		C2H2 Zn finger	463..483	CDD:275368	5/20 (25%)
		C2H2 Zn finger	492..512	CDD:275368	6/20 (30%)
		zf-C2H2	518..540	CDD:278523	7/21 (33%)
		C2H2 Zn finger	520..540	CDD:275368	7/19 (37%)
		zf-H2C2_2	532..555	CDD:290200	12/22 (55%)
		C2H2 Zn finger	548..568	CDD:275368	8/20 (40%)
		zf-H2C2_2	561..584	CDD:290200	7/23 (30%)
		C2H2 Zn finger	576..596	CDD:275368	7/19 (37%)
		zf-H2C2_2	589..610	CDD:290200	5/20 (25%)
		C2H2 Zn finger	604..624	CDD:275368	5/19 (26%)
		C2H2 Zn finger	632..652	CDD:275368	5/19 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24393
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100