DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1602 and ZNF181

DIOPT Version :9

Sequence 1:	NP_610291.2	Gene:	CG1602 / 35684	FlyBaseID:	FBgn0033186	Length:	577	Species:	Drosophila melanogaster
Sequence 2:	XP_016882229.1	Gene:	ZNF181 / 339318	HGNCID:	12971	Length:	585	Species:	Homo sapiens

Alignment Length:	413	Identity:	105/413 - (25%)
Similarity:	163/413 - (39%)	Gaps:	119/413 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   223 VVSGKQKPQSLAFSIYKLCCFLNASNDEEGATNNEKI-------KLDFSKKNKLTTDLI--EMYA 278
            :::.::.|  .|.|:||...|.:..:.:...:..:||       |.|..|||.....:|  |...
Human   156 ILTSRESP--TADSVYKYNIFRSTFHSKSTLSEPQKISAEGNSHKYDILKKNLPKKSVIKNEKVN 218

  Fly   279 NFPQLYDSNHKEFSNMSSRKQAYESMAAEISVPNVDINSDDIF-----------RAIQNLRQWYY 332
            ...:|.:||         :..|..|....:::|.. .|.:.|:           ::|.| |.|
Human   219 GGKKLLNSN---------KSGAAFSQGKSLTLPQT-CNREKIYTCSECGKAFGKQSILN-RHW-- 270

  Fly   333 KNTKHAIYAGSTAEKFYLEVCRFMPAKMYKQRLVCEFCHQITSSDHVLQSHIFKAHNIGELPFKC 397
                 .|:.|   ||.|                .|..|.:..|....|..|:. :|: ||.|:||
Human   271 -----RIHTG---EKPY----------------ECRECGKTFSHGSSLTRHLI-SHS-GEKPYKC 309

  Fly   398 TLCDRSFVGRCELANHIQRVHIG-KTHKCTHCERSFAVMSDLQLHIR------------------ 443
            ..|.::|.....|.|| |..|.| |.::|.:|.:||:.:|.|..|:|
Human   310 IECGKAFSHVSSLTNH-QSTHTGEKPYECMNCGKSFSRVSHLIEHLRIHTQEKLYECRICGKAFI 373

  Fly   444 ----------THTGHKPYVCEHCGKAFRLRSQMTLHV---------------------------T 471
                      .|||.|||.|..|||||...|.:|.|.                           .
Human   374 HRSSLIHHQKIHTGEKPYECRECGKAFCCSSHLTRHQRIHTMEKQYECNKCLKVFSSLSFLVQHQ 438

  Fly   472 AIHTKIRAFKCTMCPKDFVKKVDLSDHIKGHLNIRDKICSVCGKGFTSCHALIRHRQIHSEVKKF 536
            :|||:.:.|:|..|.|.|.:...|:.|::.|:.::...||:|||.|:...:|::|.:||:..|.:
Human   439 SIHTEEKPFECQKCRKSFNQLESLNMHLRNHIRLKPYECSICGKAFSHRSSLLQHHRIHTGEKPY 503

  Fly   537 VCKLCDSRFSQFVGLNTHMKRTH 559
            .|..|...||....|..| :|.|
Human   504 ECIKCGKTFSCSSNLTVH-QRIH 525

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1602	NP_610291.2	GT1	157..244	CDD:304916	5/20 (25%)
		MADF_DNA_bdg	273..356	CDD:287510	19/95 (20%)
		C2H2 Zn finger	367..388	CDD:275368	5/20 (25%)
		C2H2 Zn finger	397..418	CDD:275368	7/20 (35%)
		COG5048	<423..554	CDD:227381	50/185 (27%)
		C2H2 Zn finger	425..445	CDD:275368	8/47 (17%)
		zf-H2C2_2	437..460	CDD:290200	13/50 (26%)
		C2H2 Zn finger	453..470	CDD:275368	8/16 (50%)
		C2H2 Zn finger	482..502	CDD:275368	6/19 (32%)
		C2H2 Zn finger	510..530	CDD:275368	8/19 (42%)
		C2H2 Zn finger	538..559	CDD:275368	7/20 (35%)
ZNF181	XP_016882229.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165142428
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.930