DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1602 and sfc2

DIOPT Version :9

Sequence 1:	NP_610291.2	Gene:	CG1602 / 35684	FlyBaseID:	FBgn0033186	Length:	577	Species:	Drosophila melanogaster
Sequence 2:	NP_594670.1	Gene:	sfc2 / 2542887	PomBaseID:	SPAC144.09c	Length:	374	Species:	Schizosaccharomyces pombe

Alignment Length:	237	Identity:	63/237 - (26%)
Similarity:	97/237 - (40%)	Gaps:	48/237 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   368 EFCHQITSSDHVLQSHIFKAHNIGELPFKC--TLCDRSFVGRCELANHIQRVHIG-KTHKCTH-- 427
            |.|.:..|...:|:.|: :.|: .|.||.|  |.|.::|..:..|..| :|.|.. |...|.:
pombe    28 EECGKKYSRPSLLEQHL-RTHS-NERPFVCDYTGCSKAFYRKSHLKIH-KRCHTNVKPFSCHYDG 89

  Fly   428 CERSFAVMSDLQLHIRTHTGHKPYVC--EHCGKAFRLRSQMTLHVTAIHTKIRAFKCTM--CPKD 488
            |:..|.....|:.||..|...|||.|  |.|.:.|....|:..|::|.||.:..:.||.  |...
pombe    90 CDAQFYTQQHLERHIEVHRKPKPYACTWEGCDECFSKHQQLRSHISACHTHLLPYPCTYQDCELR 154

  Fly   489 FVKKVDLSDHIK-----------------GH----------LNIRD---KICSVCGKGFTSC--- 520
            |..|..|.:|:.                 ||          .:||:   ..||:||:.|.:.
pombe   155 FATKQKLQNHVNRAHEKIISYSCPHESCVGHEGFEKWSQLQNHIREAHVPSCSICGRQFKTAAHL 219

  Fly   521 -HALIRHRQIHSEVKKFVCKL--CDSRFSQFVGLNTHMKRTH 559
             |.::.|:....|.|.:.|.:  |...|::...|..|:...|
pombe   220 RHHVVLHQTTLEERKTYHCPMEGCKKSFTRSSALKKHISVIH 261

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1602	NP_610291.2	GT1	157..244	CDD:304916
		MADF_DNA_bdg	273..356	CDD:287510
		C2H2 Zn finger	367..388	CDD:275368	5/19 (26%)
		C2H2 Zn finger	397..418	CDD:275368	7/22 (32%)
		COG5048	<423..554	CDD:227381	43/172 (25%)
		C2H2 Zn finger	425..445	CDD:275368	6/21 (29%)
		zf-H2C2_2	437..460	CDD:290200	10/24 (42%)
		C2H2 Zn finger	453..470	CDD:275368	5/18 (28%)
		C2H2 Zn finger	482..502	CDD:275368	7/38 (18%)
		C2H2 Zn finger	510..530	CDD:275368	7/23 (30%)
		C2H2 Zn finger	538..559	CDD:275368	5/22 (23%)
sfc2	NP_594670.1	COG5048	1..374	CDD:227381	63/237 (27%)
		C2H2 Zn finger	28..47	CDD:275368	5/19 (26%)
		C2H2 Zn finger	55..77	CDD:275368	7/22 (32%)
		C2H2 Zn finger	85..107	CDD:275368	6/21 (29%)
		C2H2 Zn finger	115..138	CDD:275368	7/22 (32%)
		C2H2 Zn finger	146..165	CDD:275368	6/18 (33%)
		C2H2 Zn finger	206..226	CDD:275368	6/19 (32%)
		C2H2 Zn finger	238..261	CDD:275368	5/22 (23%)
		C2H2 Zn finger	269..286	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24393
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100