DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1602 and prz1

DIOPT Version :9

Sequence 1:	NP_610291.2	Gene:	CG1602 / 35684	FlyBaseID:	FBgn0033186	Length:	577	Species:	Drosophila melanogaster
Sequence 2:	NP_593073.1	Gene:	prz1 / 2541806	PomBaseID:	SPAC4G8.13c	Length:	681	Species:	Schizosaccharomyces pombe

Alignment Length:	401	Identity:	89/401 - (22%)
Similarity:	149/401 - (37%)	Gaps:	98/401 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   240 LCCFLNASNDEEGATNNEKIKLDFSKKN-KLTTDLIEMYANFPQLYD-SNHKEFSNMSS------ 296
            |..|.|||..|    :|..|..|....| ..:.||:..::....::: |...|||:.||
pombe   290 LGAFTNASPGE----SNTGIDFDTDNTNLNPSVDLLSNHSTPSFIFENSPSAEFSHQSSPYLVPN 350

  Fly   297 ------RKQAYESMAAEISVPNVDINSD-----DIF-----RAIQNLRQWYYKNTKHAIYAGSTA 345
                  .:.|.||....::.|..:.::|     .:|     .|:.|....|..|.    ::|:.
pombe   351 SGRTLNSENARESTIRSVNSPFSEDHADASLTTHVFDPISPTALSNSVLNYDSNN----FSGTP- 410

  Fly   346 EKFYLEVCRFMPAKMYKQRLVCEFCHQITSSDHVLQSHIFKAHNIGELPF--KCTLCDRSFVGRC 408
               .:.|....|:|......:        .::.:||:.|...::....|.  :..:.:.|:
pombe   411 ---QINVVPSSPSKSQSGPSL--------PANPLLQTDISITYSQSASPVSGQPAMNENSY---- 460

  Fly   409 ELAN-HIQRVHIGKTHKCTHCERSFAVMSDL-----QLHIRTHTGHKPYVC-------EHCGKAF 460
            :|.| ::....:..|:...|...|.....|.     ||:  ||..|.. .|       |..||..
pombe   461 DLQNANLCAPEMSPTYTARHRSNSAGSRFDAYEPIPQLY--THFSHSS-ECLSVNQDTELLGKIE 522

  Fly   461 RLRSQMTLHVTAIHTKIRA----------------------------FKCTM--CPKDFVKKVDL 495
            ...|:...:::..:|:.|:                            :.||.  |.|.|.:..:|
pombe   523 NDNSKSNDYLSVRNTRPRSRSLNSLVGNKSENSSSSKAKSESKSQGNYVCTFAGCNKRFTRAYNL 587

  Fly   496 SDHIKGHLNIRDKICSVCGKGFTSCHALIRHRQIHSEVKKFVCKLCDSRFSQFVGLNTHMKRT-- 558
            ..|:..|.|.|...||:|.|.|...|...||.|:|:.:|.|.|..|:.||::...||.|.|..
pombe   588 KSHMNTHTNYRPFQCSICKKSFARQHDKRRHEQLHTGIKAFACVTCNQRFARMDALNRHYKSEVG 652

  Fly   559 HNILRNNSQKG 569
            .|.||..:::|
pombe   653 QNCLRTATERG 663

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1602	NP_610291.2	GT1	157..244	CDD:304916	1/3 (33%)
		MADF_DNA_bdg	273..356	CDD:287510	19/105 (18%)
		C2H2 Zn finger	367..388	CDD:275368	3/20 (15%)
		C2H2 Zn finger	397..418	CDD:275368	3/21 (14%)
		COG5048	<423..554	CDD:227381	43/172 (25%)
		C2H2 Zn finger	425..445	CDD:275368	5/24 (21%)
		zf-H2C2_2	437..460	CDD:290200	10/34 (29%)
		C2H2 Zn finger	453..470	CDD:275368	5/23 (22%)
		C2H2 Zn finger	482..502	CDD:275368	7/21 (33%)
		C2H2 Zn finger	510..530	CDD:275368	9/19 (47%)
		C2H2 Zn finger	538..559	CDD:275368	8/22 (36%)
prz1	NP_593073.1	COG5048	121..620	CDD:227381	73/356 (21%)
		zf-C2H2	570..594	CDD:278523	7/23 (30%)
		C2H2 Zn finger	577..594	CDD:275368	5/16 (31%)
		zf-H2C2_2	586..611	CDD:290200	10/24 (42%)
		C2H2 Zn finger	602..622	CDD:275368	9/19 (47%)
		zf-H2C2_2	616..639	CDD:290200	10/22 (45%)
		C2H2 Zn finger	630..648	CDD:275368	7/17 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24393
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100