Protein Alignment CG1602 and ZNF782

DIOPT Version :10

• Sequence 1: NP_610291.2
• Gene: CG1602 / 35684
• FlyBaseID: FBgn0033186
• Length: 577
• Species: Drosophila melanogaster
• Sequence 2: NP_001001662.1
• Gene: ZNF782 / 158431
• HGNCID: 33110
• Length: 699
• Species: Homo sapiens
• Alignment Length: 546
• Identity: 134/546 - (24%)
• Similarity: 205/546 - (37%)
• Gaps: 116/546 - (21%)

  Fly    41 NVHSKVRSMEDDFEPVGENS-TESGHVDPPEEKPQAEESIFQQDESADGACVQLHIDAVRSSTNE 104
            :.|.|.:|.  :|...|||. .:|..:.|....|  |:|.::.:::.:..|...|    ::.|..
Human   235 STHPKGKSY--NFNKFGENKYDKSTFIIPQNMNP--EKSHYEFNDTGNCFCRITH----KTLTGG 291

  Fly   105 TEESDVSLVTDEEESVQDEDPSEPALDDANLKTTPTYKFHPSFFRRDHRTIKFIEIYKEHPCLWN 169
            ...|..|.:.:.........|.|.........|.|.:       :|.|.|.|:.:.   |||
Human   292 KSFSQKSHIREHHRVHIGVKPFEYGKSFNRNSTLPVH-------QRTHATDKYSDY---HPC--- 343

  Fly   170 PAHSDYKEPKKCKEALKRMAIDLEATVSVFLNEMALKLAIKKVHMQFNTVHKRVVSGKQKPQSLA 234
                             ......::|.||.          :|||:            :.||..
Human   344 -----------------TETFSYQSTFSVH----------QKVHI------------RAKPYE-- 367

  Fly   235 FSIYKLC---CFLNA-------SNDEEGATNNEKIKLDFSKKNKLTTDLIEMYANFPQLYDSNHK 289
               |..|   |.:|:       |:..|......:....||:|::|...........|...|...|
Human   368 ---YNECGKSCSMNSHLIWPQKSHTGEKPYECPECGKAFSEKSRLRKHQRTHTGEKPYKCDGCDK 429

  Fly   290 EFSNMSSRKQAYESMAAEISVPNVDINSDDIFRAIQNLRQWYYKNTKHAIYAGSTAEK-FYLEVC 353
            .||..|..:....:...|           ..|...:..:.:.||:.........|.|| |....|
Human   430 AFSAKSGLRIHQRTHTGE-----------KPFECHECGKSFNYKSILIVHQRTHTGEKPFECNEC 483

  Fly   354 RFMPAKM---------------YKQRLVCEFCHQITSSDHVLQSHIFKAH--NIGELPFKCTLCD 401
            ....:.|               ||    |:.|.:...    |:|.:.|.|  :.||.|:||..|.
Human   484 GKSFSHMSGLRNHRRTHTGERPYK----CDECGKAFK----LKSGLRKHHRTHTGEKPYKCNQCG 540

  Fly   402 RSFVGRCELANHIQRVHIG-KTHKCTHCERSFAVMSDLQLHIRTHTGHKPYVCEHCGKAFRLRSQ 465
            ::|..:.:|..| .|:|.| |.:||.||..:|:..|:|::|.|||||.|||.||.|||.||.:|.
Human   541 KAFGQKSQLRGH-HRIHTGEKPYKCNHCGEAFSQKSNLRVHHRTHTGEKPYQCEECGKTFRQKSN 604

  Fly   466 MTLHVTAIHTKIRAFKCTMCPKDFVKKVDLSDHIKGHLNIRDKICSVCGKGFTSCHALIRHRQIH 530
            :..| ...||..:.::|..|.|.|.:|..|..|.:.|...:...|:.||:.|:....|..|::.|
Human   605 LRGH-QRTHTGEKPYECNECGKAFSEKSVLRKHQRTHTGEKPYNCNQCGEAFSQKSNLRVHQRTH 668

  Fly   531 SEVKKFVCKLCDSRFSQFVGLNTHMK 556
            :..|.:.|..|...|||...|..|.|
Human   669 TGEKPYKCDKCGRTFSQKSSLREHQK 694

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1602	NP_610291.2	MADF_DNA_bdg	157..244	CDD:463144	14/89 (16%)
		MADF_DNA_bdg	273..356	CDD:463144	15/83 (18%)
		C2H2 Zn finger	367..388	CDD:275368	5/20 (25%)
		C2H2 Zn finger	397..418	CDD:275368	6/20 (30%)
		C2H2 Zn finger	425..445	CDD:275368	8/19 (42%)
		zf-H2C2_2	437..460	CDD:463886	15/22 (68%)
		C2H2 Zn finger	453..470	CDD:275368	8/16 (50%)
		C2H2 Zn finger	482..502	CDD:275368	7/19 (37%)
		C2H2 Zn finger	510..530	CDD:275368	6/19 (32%)
		C2H2 Zn finger	538..559	CDD:275368	8/19 (42%)
ZNF782	NP_001001662.1	KRAB	8..67	CDD:214630
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	75..95
		C2H2 Zn finger	291..307	CDD:275368	2/15 (13%)
		C2H2 Zn finger	314..332	CDD:275368	4/24 (17%)
		C2H2 Zn finger	343..360	CDD:275368	5/46 (11%)
		C2H2 Zn finger	369..388	CDD:275368	3/18 (17%)
		COG5048	392..697	CDD:227381	92/324 (28%)
		C2H2 Zn finger	396..416	CDD:275368	4/19 (21%)
		C2H2 Zn finger	424..444	CDD:275368	5/19 (26%)
		C2H2 Zn finger	452..472	CDD:275368	2/19 (11%)
		C2H2 Zn finger	480..500	CDD:275368	2/19 (11%)
		C2H2 Zn finger	508..528	CDD:275368	6/23 (26%)
		C2H2 Zn finger	536..556	CDD:275368	6/20 (30%)
		C2H2 Zn finger	564..584	CDD:275368	8/19 (42%)
		C2H2 Zn finger	592..612	CDD:275368	9/20 (45%)
		C2H2 Zn finger	620..640	CDD:275368	7/19 (37%)
		C2H2 Zn finger	648..668	CDD:275368	6/19 (32%)
		C2H2 Zn finger	676..696	CDD:275368	8/19 (42%)