DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1603 and sqz

DIOPT Version :9

Sequence 1:	NP_001260778.1	Gene:	CG1603 / 35683	FlyBaseID:	FBgn0033185	Length:	586	Species:	Drosophila melanogaster
Sequence 2:	NP_524403.1	Gene:	sqz / 42300	FlyBaseID:	FBgn0010768	Length:	535	Species:	Drosophila melanogaster

Alignment Length:	158	Identity:	45/158 - (28%)
Similarity:	84/158 - (53%)	Gaps:	12/158 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   412 GSESQVLYCDYCDKRFHGDYNLRVHIVKAHEVGDLPYLCSFCPRRFDRHVDMDRHKLRSHF-ERK 475
            |.:::...|..|.|.|.....|..| .:.| :|..||.|..|.|:|.:...:.:| :|:|. ::.
  Fly   152 GDQAKPYKCGSCSKSFANSSYLSQH-TRIH-LGIKPYRCEICQRKFTQLSHLQQH-IRTHTGDKP 213

  Fly   476 LKCQY--CEKSFAVDTDLKVHTLIHTGERPHVCDICGKTFRLKL-LLDH---HVNGVHLNIRPYS 534
            .||::  |.|:|:..::|:.|:..|..::|..|:.|.|.|..:: ||:|   |.:..||  :.:.
  Fly   214 YKCRHAGCPKAFSQLSNLQSHSRCHQTDKPFKCNSCYKCFSDEMTLLEHIPKHKDSKHL--KTHI 276

  Fly   535 CNMCTKTFRKKFELANHIKGHLNIRDKK 562
            ||:|.|::.::..|..|::.|....:|:
  Fly   277 CNLCGKSYTQETYLQKHLQKHAEKAEKQ 304

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1603	NP_001260778.1	MADF_DNA_bdg	202..287	CDD:287510
		GT1	321..408	CDD:304916
		C2H2 Zn finger	420..441	CDD:275368	6/20 (30%)
		COG5048	<424..583	CDD:227381	42/146 (29%)
		C2H2 Zn finger	450..471	CDD:275368	6/20 (30%)
		C2H2 Zn finger	478..498	CDD:275368	6/21 (29%)
		zf-H2C2_2	490..513	CDD:290200	7/22 (32%)
		C2H2 Zn finger	506..527	CDD:275368	8/24 (33%)
		C2H2 Zn finger	535..555	CDD:275368	6/19 (32%)
		C2H2 Zn finger	563..583	CDD:275368	45/158 (28%)
sqz	NP_524403.1	C2H2 Zn finger	160..180	CDD:275368	6/20 (30%)
		zf-H2C2_2	172..197	CDD:290200	10/26 (38%)
		zf-C2H2	186..208	CDD:278523	7/22 (32%)
		C2H2 Zn finger	188..208	CDD:275368	6/20 (30%)
		zf-C2H2_8	191..271	CDD:292531	23/80 (29%)
		zf-H2C2_2	200..227	CDD:290200	8/27 (30%)
		C2H2 Zn finger	216..238	CDD:275368	6/21 (29%)
		C2H2 Zn finger	246..266	CDD:275368	7/19 (37%)
		C2H2 Zn finger	277..297	CDD:275368	6/19 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45457123
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930