DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1603 and ZNF664

DIOPT Version :9

Sequence 1:	NP_001260778.1	Gene:	CG1603 / 35683	FlyBaseID:	FBgn0033185	Length:	586	Species:	Drosophila melanogaster
Sequence 2:	NP_001191227.1	Gene:	ZNF664 / 144348	HGNCID:	25406	Length:	261	Species:	Homo sapiens

Alignment Length:	172	Identity:	59/172 - (34%)
Similarity:	78/172 - (45%)	Gaps:	13/172 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   420 CDYCDKRFHGDYNLRVHIVKAH-----EVGDLPYLCSFCPRRFDRHVDMDRHKLRSHFERKLKCQ 479
            ||.|||.|       .||.:.|     ..|:..|.|..|.:.|.....::|||.....|:..||.
Human    33 CDKCDKGF-------FHISELHIHWRDHTGEKVYKCDDCGKDFSTTTKLNRHKKIHTVEKPYKCY 90

  Fly   480 YCEKSFAVDTDLKVHTLIHTGERPHVCDICGKTFRLKLLLDHHVNGVHLNIRPYSCNMCTKTFRK 544
            .|.|:|...:.|::|..:||||:|:||..||:.|.....|..| ..||...:|:.|..|.|.||.
Human    91 ECGKAFNWSSHLQIHMRVHTGEKPYVCSECGRGFSNSSNLCMH-QRVHTGEKPFKCEECGKAFRH 154

  Fly   545 KFELANHIKGHLNIRDKKCEYCDATFYDHSSLSRHRRSHRSE 586
            ...|..|.:.|...:..||..|...|...|||..|:|.|..|
Human   155 TSSLCMHQRVHTGEKPYKCYECGKAFSQSSSLCIHQRVHTGE 196

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1603	NP_001260778.1	MADF_DNA_bdg	202..287	CDD:287510
		GT1	321..408	CDD:304916
		C2H2 Zn finger	420..441	CDD:275368	8/20 (40%)
		COG5048	<424..583	CDD:227381	54/163 (33%)
		C2H2 Zn finger	450..471	CDD:275368	6/20 (30%)
		C2H2 Zn finger	478..498	CDD:275368	6/19 (32%)
		zf-H2C2_2	490..513	CDD:290200	11/22 (50%)
		C2H2 Zn finger	506..527	CDD:275368	6/20 (30%)
		C2H2 Zn finger	535..555	CDD:275368	7/19 (37%)
		C2H2 Zn finger	563..583	CDD:275368	8/19 (42%)
ZNF664	NP_001191227.1	C2H2 Zn finger	5..25	CDD:275368
		C2H2 Zn finger	33..53	CDD:275368	9/26 (35%)
		C2H2 Zn finger	61..81	CDD:275368	6/19 (32%)
		zf-H2C2_2	74..97	CDD:404364	8/22 (36%)
		C2H2 Zn finger	89..109	CDD:275368	6/19 (32%)
		COG5048	<94..256	CDD:227381	38/104 (37%)
		C2H2 Zn finger	117..137	CDD:275368	6/20 (30%)
		C2H2 Zn finger	145..165	CDD:275368	7/19 (37%)
		C2H2 Zn finger	173..193	CDD:275368	8/19 (42%)
		C2H2 Zn finger	201..221	CDD:275368
		C2H2 Zn finger	229..249	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S7426
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.950