Protein Alignment az2 and ZNF184

DIOPT Version :10

• Sequence 1: NP_610289.2
• Gene: az2 / 35682
• FlyBaseID: FBgn0025185
• Length: 593
• Species: Drosophila melanogaster
• Sequence 2: NP_009080.2
• Gene: ZNF184 / 7738
• HGNCID: 12975
• Length: 751
• Species: Homo sapiens
• Alignment Length: 235
• Identity: 74/235 - (31%)
• Similarity: 102/235 - (43%)
• Gaps: 38/235 - (16%)

  Fly   367 PTKSFRQKLKCEVCEHSFSTDHALQAHQFRDHKMGDGGWFRCTLCELNFDRKCHLQQHSQRVHM- 430
            |.|. .:..||..|..:||...||..|| |.| .|:.. ::|..||..|.|..:|..| ||:|.
Human   215 PVKK-EKSCKCNECGKAFSYCSALIRHQ-RTH-TGEKP-YKCNECEKAFSRSENLINH-QRIHTG 274

  Fly   431 DKSFVCEICSRSFAFGNQLAIHKRTHDEKHVAKPFVCEFCGKCFKQKIQMTTHV----------- 484
            ||.:.|:.|.:.|..|..|..|:|.|..:   ||:.|:.|||.|.|:..:..|.
Human   275 DKPYKCDQCGKGFIEGPSLTQHQRIHTGE---KPYKCDECGKAFSQRTHLVQHQRIHTGEKPYTC 336

  Fly   485 ----------------TAVHTKIRAFKCDMCPKDFLTKRDLKDHVKAHLNIRDKVCEVCQKAFTN 533
                            ..:||..:.||||.|.|.|.....|..|.|.|...:...|..|.|||..
Human   337 NECGKAFSQRGHFMEHQKIHTGEKPFKCDECDKTFTRSTHLTQHQKIHTGEKTYKCNECGKAFNG 401

  Fly   534 ANALVKHRHIHK-EKTLQCSLCTTRFSERVSLGVHMRRTH 572
            .:..::|..||. ||..:|:.|...||:..:|..| ::||
Human   402 PSTFIRHHMIHTGEKPYECNECGKAFSQHSNLTQH-QKTH 440

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
az2	NP_610289.2	MADF_DNA_bdg	157..242	CDD:463144
		MADF_DNA_bdg	276..>341	CDD:463144
		C2H2 Zn finger	377..398	CDD:275368	9/20 (45%)
		C2H2 Zn finger	408..429	CDD:275368	9/20 (45%)
		C2H2 Zn finger	436..456	CDD:275368	7/19 (37%)
		C2H2 Zn finger	467..488	CDD:275368	7/47 (15%)
		C2H2 Zn finger	496..516	CDD:275368	8/19 (42%)
		C2H2 Zn finger	524..544	CDD:275368	6/19 (32%)
		C2H2 Zn finger	551..572	CDD:275368	6/20 (30%)
ZNF184	NP_009080.2	KRAB	28..88	CDD:214630
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	191..212
		C2H2 Zn finger	224..244	CDD:275368	9/20 (45%)
		COG5048	<248..409	CDD:227381	47/165 (28%)
		C2H2 Zn finger	252..272	CDD:275368	9/20 (45%)
		C2H2 Zn finger	280..300	CDD:275368	7/19 (37%)
		C2H2 Zn finger	308..328	CDD:275368	7/19 (37%)
		C2H2 Zn finger	336..356	CDD:275368	0/19 (0%)
		COG5048	360..736	CDD:227381	29/82 (35%)
		C2H2 Zn finger	364..384	CDD:275368	8/19 (42%)
		C2H2 Zn finger	392..412	CDD:275368	6/19 (32%)
		C2H2 Zn finger	420..440	CDD:275368	6/20 (30%)
		C2H2 Zn finger	448..468	CDD:275368
		C2H2 Zn finger	476..496	CDD:275368
		C2H2 Zn finger	504..524	CDD:275368
		C2H2 Zn finger	532..552	CDD:275368
		C2H2 Zn finger	560..580	CDD:275368
		C2H2 Zn finger	588..608	CDD:275368
		C2H2 Zn finger	616..636	CDD:275368
		C2H2 Zn finger	644..664	CDD:275368
		C2H2 Zn finger	672..692	CDD:275368
		C2H2 Zn finger	700..720	CDD:275368
		C2H2 Zn finger	728..748	CDD:275368