DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment az2 and CG10654

DIOPT Version :9

Sequence 1:	NP_610289.2	Gene:	az2 / 35682	FlyBaseID:	FBgn0025185	Length:	593	Species:	Drosophila melanogaster
Sequence 2:	NP_001261767.1	Gene:	CG10654 / 39428	FlyBaseID:	FBgn0036294	Length:	412	Species:	Drosophila melanogaster

Alignment Length:	281	Identity:	67/281 - (23%)
Similarity:	113/281 - (40%)	Gaps:	62/281 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   310 LLTSEFSLGLVTHYDVY---DSIQSMRQWYSRRIKTLTDVQCVGLSLAEKQYIERCNSFMPTKSF 371
            ::.|..:||.....:||   |  :|.:|          |:....||::.|....|     ..:..
  Fly   175 VILSRITLGASLEEEVYVIED--ESAKQ----------DLGQEKLSISSKLLGAR-----KRRGV 222

  Fly   372 RQKLKCEVCEHSFSTDHALQAHQFRDHKMGDGGWFRCTLCELNFDRKCHLQQHSQRVHMDKS--- 433
            |..|:|.:|...|.....|:||..:...:..   :.|..|..::.|...|:.|.:::|.:..
  Fly   223 RHTLECRICHRGFYKPSLLEAHMQQHEGLRP---YTCVHCAKSYARANLLESHLRQMHNNADAAR 284

  Fly   434 --FVCEICSRSFAFGNQLAIH-KRTHDEKHVAKP----FVCEFCGKCFKQKIQMTTHVTAVHTKI 491
              :.|..|::.:.....|..| :|||:..|.::.    .:||.|||||.:|..:|.| ..||..:
  Fly   285 IIYACPSCNKVYTANRSLKYHMRRTHERYHESESPDARHICEECGKCFARKAHLTRH-KMVHGSV 348

  Fly   492 --RAFKCDMCPKDFLTKRDLKDHVKAHLNIRDKVCEVCQKAFTNANALVKHRHIHKEKTLQCSLC 554
              |.:.|:.|.:.|.||.::.||                         :..:|.:|...|:|..|
  Fly   349 EGRRYCCECCDRRFYTKENMVDH-------------------------LLRKHGNKNLLLRCRKC 388

  Fly   555 TTRFSERVSLGVHMRRTHKIL 575
            ...|...|.|..|.|: ||.:
  Fly   389 GRIFQNSVELNAHGRK-HKAM 408

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
az2	NP_610289.2	MADF_DNA_bdg	157..242	CDD:287510
		GT1	276..>341	CDD:304916	8/33 (24%)
		C2H2 Zn finger	377..398	CDD:275368	6/20 (30%)
		C2H2 Zn finger	408..429	CDD:275368	5/20 (25%)
		C2H2 Zn finger	436..456	CDD:275368	5/20 (25%)
		C2H2 Zn finger	467..488	CDD:275368	10/20 (50%)
		C2H2 Zn finger	496..516	CDD:275368	7/19 (37%)
		C2H2 Zn finger	524..544	CDD:275368	1/19 (5%)
		C2H2 Zn finger	551..572	CDD:275368	7/20 (35%)
CG10654	NP_001261767.1	zf-AD	39..115	CDD:285071
		C2H2 Zn finger	228..248	CDD:275368	6/19 (32%)
		C2H2 Zn finger	256..313	CDD:275368	13/56 (23%)
		C2H2 Zn finger	289..314	CDD:275368	7/24 (29%)
		zf-C2H2	323..345	CDD:278523	10/22 (45%)
		C2H2 Zn finger	325..345	CDD:275368	10/20 (50%)
		C2H2 Zn finger	355..376	CDD:275368	7/45 (16%)
		C2H2 Zn finger	385..405	CDD:275368	7/20 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45440003
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24409
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030