DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment az2 and CG1529

DIOPT Version :9

Sequence 1:	NP_610289.2	Gene:	az2 / 35682	FlyBaseID:	FBgn0025185	Length:	593	Species:	Drosophila melanogaster
Sequence 2:	NP_001138223.2	Gene:	CG1529 / 33077	FlyBaseID:	FBgn0031144	Length:	512	Species:	Drosophila melanogaster

Alignment Length:	225	Identity:	62/225 - (27%)
Similarity:	95/225 - (42%)	Gaps:	24/225 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   372 RQKLKCEVCEHSFSTDHALQAHQFRDHKMGDGGWFRCTLCELNFDRKCHLQQHSQRVHMD----- 431
            |..|.|:.|.........|:|| .|....|....|.|..|:.:|.|...|:.|.:..|..
  Fly   166 RAGLACDQCGKQVYKLPYLEAH-IRSVHQGYSKPFLCRSCDKSFTRYEQLRSHMRNAHPQLEQLQ 229

  Fly   432 ---KSFVCEICSRSFAFGNQLAIHKRTHDEKHVAKPFVCEFCGKCFKQKIQMTTHVTAVHTKIRA 493
               :..:||:|:|.::..|.|..|.:.|.::   |..|||.||.....:.::.||:...:.....
  Fly   230 QELRDLICELCNRQYSTKNALGEHLKRHAQR---KEHVCEHCGVAKVTRTELLTHLRTHNPTWER 291

  Fly   494 FKCDMCPKDFLTKRDLKDHVK-AHLNIRDKVCEVCQKAFTNANALVKHRHIHKEKT--------- 548
            |||:.||:.|..|..:..||: .|...|...|..|:|.|....:.|:|..:|.|.|
  Fly   292 FKCEQCPQLFRHKSAISRHVRVVHEGQRRFQCGHCEKKFGTHASQVRHERLHTESTGSGEAAEEW 356

  Fly   549 -LQCSLCTTRFSERVSLGVHMRRTHKILKS 577
             ..|..|......|.:|.:|:|| |:..|:
  Fly   357 PFACIHCQKPCVSRQTLELHLRR-HRARKT 385

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
az2	NP_610289.2	MADF_DNA_bdg	157..242	CDD:287510
		GT1	276..>341	CDD:304916
		C2H2 Zn finger	377..398	CDD:275368	6/20 (30%)
		C2H2 Zn finger	408..429	CDD:275368	6/20 (30%)
		C2H2 Zn finger	436..456	CDD:275368	7/19 (37%)
		C2H2 Zn finger	467..488	CDD:275368	6/20 (30%)
		C2H2 Zn finger	496..516	CDD:275368	7/20 (35%)
		C2H2 Zn finger	524..544	CDD:275368	6/19 (32%)
		C2H2 Zn finger	551..572	CDD:275368	7/20 (35%)
CG1529	NP_001138223.2	zf-AD	11..79	CDD:285071
		C2H2 Zn finger	171..192	CDD:275368	6/21 (29%)
		zf-C2H2_2	201..>257	CDD:289522	14/55 (25%)
		C2H2 Zn finger	201..222	CDD:275368	6/20 (30%)
		C2H2 Zn finger	237..257	CDD:275368	7/19 (37%)
		C2H2 Zn finger	265..285	CDD:275368	6/19 (32%)
		zf-C2H2_8	268..349	CDD:292531	24/80 (30%)
		C2H2 Zn finger	294..315	CDD:275368	7/20 (35%)
		C2H2 Zn finger	323..343	CDD:275368	6/19 (32%)
		C2H2 Zn finger	360..380	CDD:275368	7/20 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24409
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100