Protein Alignment az2 and LOC3290988

DIOPT Version :10

• Sequence 1: NP_610289.2
• Gene: az2 / 35682
• FlyBaseID: FBgn0025185
• Length: 593
• Species: Drosophila melanogaster
• Sequence 2: XP_061506709.1
• Gene: LOC3290988 / 3290988
• VectorBaseID: AGAMI1_013696
• Length: 1078
• Species: Anopheles gambiae
• Alignment Length: 678
• Identity: 137/678 - (20%)
• Similarity: 233/678 - (34%)
• Gaps: 190/678 - (28%)

  Fly    22 HQN----DC-YVEMEFKRWREFIVHV-KEHLEANPSMQQELTTSEVISSAKCEEEVSPAKVFIVE 80
            |:|    .| |....:.|..:..||: |||.:..|                          |...
Mosquito   417 HENVHPFKCGYCSKTYGRNYKLQVHIRKEHTKERP--------------------------FACS 455

  Fly    81 EPPENCLAE-DMFVDVPPSSENDESTSPVEEEEEEDDEVDSSSMTVD---------CELGTRNST 135
            :.||..... :|...........|....||.|.|..|....:..|::         .|..|:..|
Mosquito   456 DCPERFFQRWEMLGHQRVEHGKMEGIESVELETELHDTFTCNYTTLEELLKMNWSSAENSTQKWT 520

  Fly   136 HFAPLTKFNPTFYRRSPRIT-QFIELYKQQTCLWDPADESYR---DKEKRANAYEELLEQLKATV 196
            .|..||..:|.      ::| :.|.|..|.........|.||   .|..|| ||.:...::...|
Mosquito   521 FFEQLTLEDPV------QVTARRILLSNQGVLCLGIIQEFYRIIPIKTNRA-AYGKATNRIWILV 578

  Fly   197 NLHLTAYKLKKCITSLHA---QYASISRQKKTQKLTKVPLYYHGKYSFLAERG-SLEDA------ 251
             :..:.:.:|.|...|..   :|.||.::.....|.::   :|........|| .|.|.
Mosquito   579 -VKYSGFTMKTCRACLQKEADEYCSIFKKINQATLDEM---FHSLTGIRVSRGDGLPDCVCQECS 639

  Fly   252 ------------------------DSDDVDG-------DGKIKLVF----TEENQLTTQFIDLYS 281
                                    .::|.:|       |.:.:.|.    :|||.||.:...|..
Mosquito   640 DFIVMCNNFRKKCLKSDVQLRALLPTEDSEGEHFQTTQDSERQSVHETDCSEENPLTEEECQLVI 704

  Fly   282 KFPQLYDPAHKHFCNLNVRKSSLIEITDLLTSEFSL----GLV-------THYDVYD-------- 327
            |     |.|       ::.:..|...|::|..:..:    .::       ::|::||
Mosquito   705 K-----DHA-------DIYEEDLCSETEILVEQLDVEDGKSIIEQTADHESYYELYDVVEDVEFG 757

  Fly   328 -------------------SIQSMRQWYSRRIKTLTD---------VQCVGLSLAE-------KQ 357
                               .|:|.::.:...:....:         |:|.|....:       ||
Mosquito   758 EIEALNECEDDDSQDAIIERIESRQETHESSVDDPVESTVQATEFVVECCGCPGVQFPSADELKQ 822

  Fly   358 YIERCNSFMPTKSFRQKLKCEVCEHSFSTDHALQAHQ---FRDHKMGDGGWFRCTLCELNFDRKC 419
            :..:.:......:..:..:|::|...|.:..||..||   :|..|.|      |..|..:|..:.
Mosquito   823 HTAQVHENERILTNLRPYECDICYKRFISHAALSKHQAAPYRKKKYG------CQTCGASFCSRS 881

  Fly   420 HLQQHSQRVH-MDKSFVCEICSRSFAFGNQLAIHKRTHDEKHVAKPFVCEFCGKCFKQKIQMTTH 483
            .|..|:...| .|:.:||::|.:.|...:.:..|::.|.|    |.:.|..|.|.|.::..:.:|
Mosquito   882 ALHGHTNSAHTRDRKYVCDVCQKGFYTSSTMLSHRQIHGE----KKYQCSTCAKKFLRQSDLLSH 942

  Fly   484 VTAVHTKIRAFKCDMCPKDFLTKRDLKDHVKAHLNIRDKVCEVCQKAF-TNANALV---KHRHIH 544
             ...|:..|.:.|..|...|..:..|:||...|...|.|.|.:|.|.| |..:..|   :|.::|
Mosquito   943 -QMTHSDERPYGCGECEMRFKCRSHLRDHQTVHTGERTKKCRICGKGFGTYGDRRVHELRHENVH 1006

  Fly   545 KEKTLQCSLCTTRFSERVSLGVHMRRTH 572
            ..|   |..|:..:.....|.||:|:.|
Mosquito  1007 PFK---CGYCSKTYGRNYKLQVHIRKEH 1031

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
az2	NP_610289.2	MADF_DNA_bdg	157..242	CDD:463144	20/90 (22%)
		MADF_DNA_bdg	276..>341	CDD:463144	12/102 (12%)
		C2H2 Zn finger	377..398	CDD:275368	8/23 (35%)
		C2H2 Zn finger	408..429	CDD:275368	5/20 (25%)
		C2H2 Zn finger	436..456	CDD:275368	4/19 (21%)
		C2H2 Zn finger	467..488	CDD:275368	5/20 (25%)
		C2H2 Zn finger	496..516	CDD:275368	6/19 (32%)
		C2H2 Zn finger	524..544	CDD:275368	7/23 (30%)
		C2H2 Zn finger	551..572	CDD:275368	6/20 (30%)
LOC3290988	XP_061506709.1	None