DRSC/TRiP Functional Genomics Resources

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Protein Alignment az2 and ZFP92

DIOPT Version :9

Sequence 1:NP_610289.2 Gene:az2 / 35682 FlyBaseID:FBgn0025185 Length:593 Species:Drosophila melanogaster
Sequence 2:NP_001129745.1 Gene:ZFP92 / 139735 HGNCID:12865 Length:416 Species:Homo sapiens


Alignment Length:221 Identity:65/221 - (29%)
Similarity:94/221 - (42%) Gaps:28/221 - (12%)


- Green bases have known domain annotations that are detailed below.


  Fly   354 AEKQYIERCNSFMPTKSFRQKLKCEVCEHSFSTDHALQAHQFRDHKMGDGGWFRCTLCELNFDRK 418
            |||:|:                 |:.|..:||....|..|  |....|:.. :.|..|...|.|.
Human   148 AEKRYL-----------------CQQCGKAFSRSSNLIKH--RIIHSGEKP-YACPECGKLFRRS 192

  Fly   419 CHLQQHSQRVHM-DKSFVCEICSRSFAFGNQLAIHKRTHDEKHVAKPFVCEFCGKCFKQKIQMTT 482
            ..|.:| ||:|. :|.:.|..||::|...:.|..|:..|..:   :||.|..|||.|::...:..
Human   193 FALLEH-QRIHSGEKPYACPECSKTFTRSSNLIKHQVIHSGE---RPFACGDCGKLFRRSFALLE 253

  Fly   483 HVTAVHTKIRAFKCDMCPKDFLTKRDLKDHVKAHLNIRDKVCEVCQKAFTNANALVKHRHIHK-E 546
            | ..||:..|.:.|..|.|.|....:|.:|.:.|...:...|..|.|||...:.|:.|:..|. |
Human   254 H-ARVHSGERPYACPECGKAFSRSSNLIEHQRTHRGEKPYACGQCAKAFKGVSQLIHHQRSHSGE 317

  Fly   547 KTLQCSLCTTRFSERVSLGVHMRRTH 572
            :...|..|...|..|..|..| ||.|
Human   318 RPFACRECGKAFRGRSGLSQH-RRVH 342

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
az2NP_610289.2 MADF_DNA_bdg 157..242 CDD:287510
GT1 276..>341 CDD:304916
C2H2 Zn finger 377..398 CDD:275368 7/20 (35%)
C2H2 Zn finger 408..429 CDD:275368 8/20 (40%)
C2H2 Zn finger 436..456 CDD:275368 6/19 (32%)
C2H2 Zn finger 467..488 CDD:275368 6/20 (30%)
C2H2 Zn finger 496..516 CDD:275368 6/19 (32%)
C2H2 Zn finger 524..544 CDD:275368 7/19 (37%)
C2H2 Zn finger 551..572 CDD:275368 8/20 (40%)
ZFP92NP_001129745.1 KRAB 14..74 CDD:214630
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 86..125
COG5048 <145..286 CDD:227381 46/162 (28%)
C2H2 Zn finger 154..174 CDD:275368 7/21 (33%)
C2H2 Zn finger 182..202 CDD:275368 8/20 (40%)
C2H2 Zn finger 210..230 CDD:275368 6/19 (32%)
C2H2 Zn finger 238..258 CDD:275368 6/20 (30%)
COG5048 262..>315 CDD:227381 15/52 (29%)
C2H2 Zn finger 266..286 CDD:275368 6/19 (32%)
C2H2 Zn finger 294..314 CDD:275368 7/19 (37%)
C2H2 Zn finger 322..342 CDD:275368 8/20 (40%)
zf-H2C2_2 335..359 CDD:404364 5/9 (56%)
C2H2 Zn finger 350..370 CDD:275368
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 368..416
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165142176
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.840

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