DRSC/TRiP Functional Genomics Resources

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Protein Alignment az2 and Zfp764

DIOPT Version :9

Sequence 1:NP_610289.2 Gene:az2 / 35682 FlyBaseID:FBgn0025185 Length:593 Species:Drosophila melanogaster
Sequence 2:XP_006230431.1 Gene:Zfp764 / 102553866 RGDID:7540019 Length:461 Species:Rattus norvegicus


Alignment Length:453 Identity:97/453 - (21%)
Similarity:162/453 - (35%) Gaps:118/453 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly   152 PRITQFIELYKQQTCLWDPADESYRDKEKRANAYEELLEQLKATVNLHLTAYKLKKCITSLHAQY 216
            |.:..::|   ::|.||.|          ||...|                  :..|.|.:|:..
  Rat    68 PALICWVE---EETELWGP----------RAQDPE------------------VAMCKTEVHSDC 101

  Fly   217 ASISRQKKTQKLTKVPLYYHGKYSFLAERGSLEDADSDDVDGDGKIKLVFTEENQLTTQFIDLYS 281
            ....:::|.::.|:..     :.:|..|.|..|...|            |.    .:..:::|.|
  Rat   102 RQEEKRRKPREETEAI-----QRTFSTEAGPKEPCPS------------FA----ASPSYLELLS 145

  Fly   282 KFPQ-------LYDPAHK-------HFCNLN-VRKSSLIEITDLLTSEFSLGLVTHYDVYDSIQS 331
            |.||       |:|...|       |.|..: .|:|.|:|           .|.||..       
  Rat   146 KDPQQGQPTVPLHDTVLKADQRHGCHVCGKSFTRQSKLVE-----------HLYTHTG------- 192

  Fly   332 MRQWYSRRIKTLTDVQCVGLSLAEKQYIERCNSFMPTKSFRQKLK---CEVCEHSFSTDHALQAH 393
                 .:..:.....:|.|          |.:|....::..::.:   |..|..||:....|.||
  Rat   193 -----EKPFQCSECNKCFG----------RASSLSMHRAIHRRERPHCCPDCGKSFTQRSTLVAH 242

  Fly   394 QFRDHKMGDGGWFRCTLCELNFDRKCHLQQHSQRVHM-DKSFVCEICSRSFAFGNQLAIHKRTHD 457
            .:.  ..|:.. |||..|..:|.....|..| :.:|. ::...|..|.|:|...:.|..|.|.|.
  Rat   243 MYT--HTGEKP-FRCPDCNKSFSWPSSLSTH-RAIHRGERPHCCPDCGRAFTHRSGLITHLRVHT 303

  Fly   458 EKHVAKPFVCEFCGKCFKQKIQMTTHVTAVHTKIRAFKCDMCPKDFLTKRDLKDHVKAHLNIRDK 522
            .:   ||:.|..||:||.|...::.|...||:.:..|.|..|.:.|.....|:.|::.|...:..
  Rat   304 GE---KPYCCADCGRCFSQSSGLSEHQRVVHSGMTPFSCTHCGRAFARAAYLRCHMRTHTGEKPY 365

  Fly   523 VCEVCQKAFTNANALVKHRHIHK-EKTLQCSLCTTRFSERVSLGVHM------RRTHKILKSS 578
            .|..|.:.|...:.:..||..|. |:...|..|...|..:.::..|.      .:.|:..|:|
  Rat   366 SCPDCGRCFRQGSDMAAHRRTHSGERPYPCPQCGRGFPTKSAMTKHQWVHRPGAKGHRDRKAS 428

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
az2NP_610289.2 MADF_DNA_bdg 157..242 CDD:287510 13/84 (15%)
GT1 276..>341 CDD:304916 17/79 (22%)
C2H2 Zn finger 377..398 CDD:275368 7/20 (35%)
C2H2 Zn finger 408..429 CDD:275368 5/20 (25%)
C2H2 Zn finger 436..456 CDD:275368 7/19 (37%)
C2H2 Zn finger 467..488 CDD:275368 7/20 (35%)
C2H2 Zn finger 496..516 CDD:275368 5/19 (26%)
C2H2 Zn finger 524..544 CDD:275368 5/19 (26%)
C2H2 Zn finger 551..572 CDD:275368 4/26 (15%)
Zfp764XP_006230431.1 KRAB 22..81 CDD:214630 3/15 (20%)
KRAB 22..60 CDD:279668
C2H2 Zn finger 170..190 CDD:275368 7/30 (23%)
zf-H2C2_2 183..207 CDD:290200 7/56 (13%)
C2H2 Zn finger 198..218 CDD:275368 4/29 (14%)
zf-H2C2_2 210..235 CDD:290200 5/24 (21%)
COG5048 <223..383 CDD:227381 45/166 (27%)
C2H2 Zn finger 226..246 CDD:275368 7/21 (33%)
zf-H2C2_2 239..262 CDD:290200 8/25 (32%)
C2H2 Zn finger 254..274 CDD:275368 5/20 (25%)
zf-H2C2_2 266..291 CDD:290200 7/25 (28%)
C2H2 Zn finger 282..302 CDD:275368 7/19 (37%)
zf-H2C2_2 295..319 CDD:290200 11/26 (42%)
C2H2 Zn finger 310..329 CDD:275368 7/18 (39%)
C2H2 Zn finger 339..359 CDD:275368 5/19 (26%)
zf-H2C2_2 351..376 CDD:290200 6/24 (25%)
C2H2 Zn finger 367..387 CDD:275368 5/19 (26%)
zf-H2C2_2 383..402 CDD:290200 6/18 (33%)
C2H2 Zn finger 395..415 CDD:275368 4/19 (21%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C166335910
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.930

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