DRSC/TRiP Functional Genomics Resources

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Protein Alignment az2 and E430018J23Rik

DIOPT Version :9

Sequence 1:NP_610289.2 Gene:az2 / 35682 FlyBaseID:FBgn0025185 Length:593 Species:Drosophila melanogaster
Sequence 2:NP_932128.2 Gene:E430018J23Rik / 101604 MGIID:2141981 Length:461 Species:Mus musculus


Alignment Length:216 Identity:61/216 - (28%)
Similarity:92/216 - (42%) Gaps:16/216 - (7%)


- Green bases have known domain annotations that are detailed below.


  Fly   376 KCEVCEHSFSTDHALQAHQFRDHKMGDGGWFRCTLCELNFDRKCHLQQHSQRVHM-DKSFVCEIC 439
            :|..|..||:....|.||.:.  ..|:.. |.|..|..:|.|...|..| :.:|. ::...|..|
Mouse   225 QCPDCGKSFTQRSTLVAHMYT--HTGEKP-FHCPDCNKSFSRPSSLSSH-RAIHRGERPHCCSDC 285

  Fly   440 SRSFAFGNQLAIHKRTHDEKHVAKPFVCEFCGKCFKQKIQMTTHVTAVHTKIRAFKCDMCPKDFL 504
            .|:|...:.|..|.|.|..:   ||:.|..||:||.|...:..|...||:.:..|.|..|.:.|.
Mouse   286 GRAFTHRSGLIAHLRVHTGE---KPYCCADCGRCFSQSSGLREHQRVVHSGVTPFTCTHCGRAFA 347

  Fly   505 TKRDLKDHVKAHLNIRDKVCEVCQKAFTNANALVKHRHIHK-EKTLQCSLCTTRFSERVSLGVHM 568
            ....|:.|::.|...:...|..|.:.|..::.:..||..|. |:...|..|..||..:.::..|.
Mouse   348 RAAYLQCHMRTHTGEKPYSCPDCGRCFRQSSDMAAHRRTHSGERPYPCPQCGRRFPTKSAVTKHQ 412

  Fly   569 ------RRTHKILK-SSLSSS 582
                  .:.||..| |.||.|
Mouse   413 WVHRPGAKGHKDKKFSQLSIS 433

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
az2NP_610289.2 MADF_DNA_bdg 157..242 CDD:287510
GT1 276..>341 CDD:304916
C2H2 Zn finger 377..398 CDD:275368 7/20 (35%)
C2H2 Zn finger 408..429 CDD:275368 6/20 (30%)
C2H2 Zn finger 436..456 CDD:275368 7/19 (37%)
C2H2 Zn finger 467..488 CDD:275368 7/20 (35%)
C2H2 Zn finger 496..516 CDD:275368 5/19 (26%)
C2H2 Zn finger 524..544 CDD:275368 5/19 (26%)
C2H2 Zn finger 551..572 CDD:275368 5/26 (19%)
E430018J23RikNP_932128.2 KRAB 22..81 CDD:214630
KRAB 22..61 CDD:279668
C2H2 Zn finger 170..190 CDD:275368
zf-H2C2_2 183..207 CDD:290200
C2H2 Zn finger 198..218 CDD:275368
zf-H2C2_2 210..235 CDD:290200 4/9 (44%)
COG5048 <223..383 CDD:227381 45/164 (27%)
C2H2 Zn finger 226..246 CDD:275368 7/21 (33%)
zf-H2C2_2 239..259 CDD:290200 7/22 (32%)
C2H2 Zn finger 254..302 CDD:275368 14/48 (29%)
zf-H2C2_2 298..319 CDD:290200 10/23 (43%)
C2H2 Zn finger 310..331 CDD:275368 7/20 (35%)
C2H2 Zn finger 339..359 CDD:275368 5/19 (26%)
zf-H2C2_2 351..376 CDD:290200 6/24 (25%)
C2H2 Zn finger 367..387 CDD:275368 5/19 (26%)
zf-H2C2_2 383..402 CDD:290200 6/18 (33%)
C2H2 Zn finger 395..415 CDD:275368 5/19 (26%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C167832246
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.930

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