DRSC/TRiP Functional Genomics Resources

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Protein Alignment az2 and LOC100365363

DIOPT Version :9

Sequence 1:NP_610289.2 Gene:az2 / 35682 FlyBaseID:FBgn0025185 Length:593 Species:Drosophila melanogaster
Sequence 2:XP_006228060.2 Gene:LOC100365363 / 100365363 RGDID:2319215 Length:670 Species:Rattus norvegicus


Alignment Length:427 Identity:107/427 - (25%)
Similarity:153/427 - (35%) Gaps:129/427 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly   272 LTTQFIDLYSKFPQLYDPAHKHFCNLNVRKSSLIEI--------------------TDLLTSE-- 314
            :|.|.::..||..|...|.......:..|||::.|.                    :.:|:|:  
  Rat    49 MTLQSLNAVSKLEQNKGPWTVESEAIITRKSNVQEYAIAMNAENIDCMEAKSISNGSSILSSDRI 113

  Fly   315 FSLG----LVTHYDVYDSIQSMRQWYSRRIKTLTDVQCVGLSLAEKQYIERCNS----FMPTKSF 371
            |..|    .|..||||.|:....|               ..::.||.|  :||.    |..|.|.
  Rat   114 FLSGDKAPFVHEYDVYSSLLMKGQ---------------KAAIKEKPY--QCNECDKVFRYTSSL 161

  Fly   372 R--------QKL-KCEVCEHSFSTDHALQAHQFRDHKMGDGGWFRCTLCELNFDRKCHLQQHSQR 427
            .        :|| ||..|..:|.....|..|: |.|.....  ::|..|...|.:..||:.| :|
  Rat   162 AYHRQIHTGEKLYKCVECGKAFFRRSYLLVHE-RHHSGAKP--YKCNECGKVFSQNSHLKSH-RR 222

  Fly   428 VHM-----------------------------DKSFVCEICSRSFAFGNQLAIHKRTH-DEK--- 459
            :|.                             ||.:.|..|.:.|:..:.|.||:||| .||   
  Rat   223 IHTGEKPYKCNDCGKAFSVRSNLTHHLVIHTGDKPYKCNECGKVFSQTSSLTIHRRTHTGEKPYR 287

  Fly   460 ----------------HVA-----KPFVCEFCGKCFKQKIQMTTHVTAVHTKIRAFKCDMCPKDF 503
                            |.|     ||:.|..|||.|.|...:..| ...||..:.:||:.|.|.|
  Rat   288 CNECGKVFSSHSNLNTHQAIHTGEKPYKCSECGKVFTQNSHLANH-WRTHTGEKPYKCNECGKAF 351

  Fly   504 LTKRDLKDHVKAHLNIRDKVCEVCQKAFTNANALVKHRHIHK-EKTLQCSLCTTRFSERVSLGVH 567
            .....|..|:..|...:...||.|.|.||..:.|..||.||. ||..:|..|...|::..:|..|
  Rat   352 SVYSSLTTHLAIHTGEKPYKCEECGKVFTQNSHLANHRGIHSGEKPYKCEECGKHFNQTSNLARH 416

  Fly   568 MR-----RTHKI--------LKSSLSSSDALFTKTFP 591
            .|     :.:|.        ::|||:|...:.|...|
  Rat   417 WRVHTGEKPYKCSECGKAFSVRSSLTSHQVIHTGEKP 453

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
az2NP_610289.2 MADF_DNA_bdg 157..242 CDD:287510
GT1 276..>341 CDD:304916 19/90 (21%)
C2H2 Zn finger 377..398 CDD:275368 6/20 (30%)
C2H2 Zn finger 408..429 CDD:275368 7/20 (35%)
C2H2 Zn finger 436..456 CDD:275368 7/19 (37%)
C2H2 Zn finger 467..488 CDD:275368 7/20 (35%)
C2H2 Zn finger 496..516 CDD:275368 6/19 (32%)
C2H2 Zn finger 524..544 CDD:275368 9/19 (47%)
C2H2 Zn finger 551..572 CDD:275368 6/25 (24%)
LOC100365363XP_006228060.2 KRAB 8..68 CDD:214630 6/18 (33%)
SFP1 <143..221 CDD:227516 24/83 (29%)
C2H2 Zn finger 148..168 CDD:275368 5/19 (26%)
C2H2 Zn finger 176..196 CDD:275368 6/20 (30%)
COG5048 200..575 CDD:227381 68/258 (26%)
C2H2 Zn finger 204..224 CDD:275368 7/20 (35%)
C2H2 Zn finger 232..252 CDD:275368 0/19 (0%)
C2H2 Zn finger 260..280 CDD:275368 7/19 (37%)
C2H2 Zn finger 288..308 CDD:275368 2/19 (11%)
C2H2 Zn finger 316..336 CDD:275368 7/20 (35%)
C2H2 Zn finger 344..364 CDD:275368 6/19 (32%)
C2H2 Zn finger 372..392 CDD:275368 9/19 (47%)
C2H2 Zn finger 400..420 CDD:275368 6/19 (32%)
C2H2 Zn finger 428..448 CDD:275368 4/19 (21%)
C2H2 Zn finger 456..476 CDD:275368
C2H2 Zn finger 484..504 CDD:275368
C2H2 Zn finger 512..532 CDD:275368
C2H2 Zn finger 540..560 CDD:275368
C2H2 Zn finger 568..588 CDD:275368
zf-H2C2_2 580..604 CDD:404364
C2H2 Zn finger 596..615 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C166335944
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.930

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