DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mEFTu2 and RABE1b

DIOPT Version :9

Sequence 1:	NP_610288.1	Gene:	mEFTu2 / 35681	FlyBaseID:	FBgn0033184	Length:	456	Species:	Drosophila melanogaster
Sequence 2:	NP_001329775.1	Gene:	RABE1b / 827784	AraportID:	AT4G20360	Length:	476	Species:	Arabidopsis thaliana

Alignment Length:	431	Identity:	195/431 - (45%)
Similarity:	273/431 - (63%)	Gaps:	23/431 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 SQALIGPGASQSRWTGTRLLATSADKNPAPGL--RELPHCNVGTIGHVDHGKTTLTAAITRIQSQ 83
            |.:|....||||    ||   .|.....|.|.  |:.||.|:||||||||||||||||:|...:.
plant    48 SYSLTTTSASQS----TR---RSFTVRAARGKFERKKPHVNIGTIGHVDHGKTTLTAALTMALAS 105

  Fly    84 KGLAEYLSYDQIDRAPEEKARGITINACHIGYSTTERTYAHTDCPGHADYIKNMISGASQMDGAI 148
            .|.:....||:||.||||:|||||||...:.|.|..|.|||.||||||||:||||:||:||||||
plant   106 IGSSVAKKYDEIDAAPEERARGITINTATVEYETENRHYAHVDCPGHADYVKNMITGAAQMDGAI 170

  Fly   149 LVVAATDGQMPQTREHLLLAKQVGIQRIIVFINKADLVDQ-EVLELVEIEMREMLSDFGFDGVNS 212
            |||:..||.||||:||:|||||||:..::||:||.|.||. |:|||||:|:||:||.:.|:|.:.
plant   171 LVVSGADGPMPQTKEHILLAKQVGVPDMVVFLNKEDQVDDAELLELVELEVRELLSSYEFNGDDI 235

  Fly   213 PVICGSALLAL----REDKSEFG----VPSIEKLLEQCDSYIPTPQRDISSPFILPIDNAFTVPG 269
            |:|.||||||:    ...|.:.|    |..|.:|::..|.|||.|||....||:|.:::.|::.|
plant   236 PIISGSALLAVETLTENPKVKRGDNKWVDKIYELMDAVDDYIPIPQRQTELPFLLAVEDVFSITG 300

  Fly   270 RGTVVVGTIKRGTIPRNADADLLGFNQNLKTSISDIQIFRKSVPQAQAGENVGALLRGIKISAVE 334
            ||||..|.::|||:......||:|..:....:::.:::|:|.:.:|.||:|||.|||||:.:.::
plant   301 RGTVATGRVERGTVKVGETVDLVGLRETRSYTVTGVEMFQKILDEALAGDNVGLLLRGIQKADIQ 365

  Fly   335 RGMLLCATGSEDISNHFEGSMYLLSRAEGGRVKPMLSKYIQQLFSQTWNVPARIDIVPSE----- 394
            |||:|...||......||..:|:|.:.||||..|..:.|..|.:.:|.:|..::..:.::
plant   366 RGMVLAKPGSITPHTKFEAIIYVLKKEEGGRHSPFFAGYRPQFYMRTTDVTGKVTKIMNDKDEES 430

  Fly   395 AMLMPGEHGQVRVTLLRKMVMTPGQAFTIRENGATVATGMV 435
            .|:|||:..::.|.|:..:....|..|.|||.|.||..|::
plant   431 KMVMPGDRVKIVVELIVPVACEQGMRFAIREGGKTVGAGVI 471

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mEFTu2	NP_610288.1	PRK00049	53..437	CDD:234596	184/397 (46%)
		EF_Tu	56..249	CDD:206671	117/201 (58%)
		EFTU_II	257..343	CDD:293898	32/85 (38%)
		mtEFTU_III	347..437	CDD:294005	28/94 (30%)
RABE1b	NP_001329775.1	PLN03126	17..476	CDD:215592	195/431 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0050
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D491836at2759
OrthoFinder	1	1.000	-	-		FOG0002097
OrthoInspector	1	1.000	-	-		mtm1013
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR43721
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	8	7.880