DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mEFTu2 and eef2a.1

DIOPT Version :9

Sequence 1:	NP_610288.1	Gene:	mEFTu2 / 35681	FlyBaseID:	FBgn0033184	Length:	456	Species:	Drosophila melanogaster
Sequence 2:	NP_001038626.2	Gene:	eef2a.1 / 792182	ZFINID:	ZDB-GENE-050522-500	Length:	854	Species:	Danio rerio

Alignment Length:	416	Identity:	93/416 - (22%)
Similarity:	155/416 - (37%)	Gaps:	115/416 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    59 NVGTIGHVDHGKTTLTAAITRIQSQKGLAEYLSYDQ---IDRAPEEKARGITI--NACHIGYSTT 118
            |:..||..||||:|||..:.   |:.|:.......:   :|...:|:.|.|||  .|..|.|...
Zfish    21 NMSVIGAFDHGKSTLTDWLV---SEAGIVSSARAGETRFMDTRRDEQERCITIKSTAISIFYELA 82

  Fly   119 ERTYAH--------------TDCPGHADYIKNMISGASQMDGAILVVAATDGQMPQTREHLLLAK 169
            |:..|.              .|.|||.|:...:.:.....|||:|||....|...||  ..:|.:
Zfish    83 EKDLAFIKECKDGSGFLLNLIDSPGHVDFSSEVTAALRITDGALLVVDCVSGVCLQT--ETVLRQ 145

  Fly   170 QVGIQRI--IVFINKAD-------LVDQE-------VLELVEIEMREMLSD----FG---FDGVN 211
            .:| :||  ::.|||.|       ||.:|       ::|.|.:.:.....|    .|   .|.|.
Zfish   146 AIG-ERIKPVLMINKMDRALLELQLVPEELYQIFQRIVEKVNVTISTYAEDEKGPMGNVMIDPVI 209

  Fly   212 SPVICGSAL----LALRE----------DKSEFG----VPSIEKLLEQC--DSYIPTP----QRD 252
            ..:..||.|    ..|::          .|::.|    :..:|.::::.  |||..:.    ...
Zfish   210 GNLAFGSGLHGWAFTLKQFAELYVKKFAGKAQLGPEEYIKKVEDMIKRLWGDSYFDSTTGKFSES 274

  Fly   253 ISSP--------FI-LPIDNAFTV----------------------------PGRGTVVVGTIKR 280
            .:||        |: |.:|..|.|                            ...|.:::..:.|
Zfish   275 ATSPDGKKLPRTFVHLVLDPIFKVFDAIMNFKKEETVKLIEKMGIKLDVEDKEKEGKILLKAVMR 339

  Fly   281 GTIPRNADADLLGFNQNLKTSISDIQIFRKSVPQAQAGENVGALLRGIKISAVERGMLLCATGSE 345
            ..:|. .:|.|.....:|.:.:: .||:|..:.....|::..|:  |||....:..:::..  |:
Zfish   340 CWLPA-GEALLQMITIHLPSPVT-AQIYRCELLYEGPGDDEAAM--GIKNCDPKAPLMMYI--SK 398

  Fly   346 DISNHFEGSMYLLSRAEGGRVKPMLS 371
            .|....:|..|...|...|.|...|:
Zfish   399 MIPTSDKGCFYAFGRVFSGCVSTGLN 424

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mEFTu2	NP_610288.1	PRK00049	53..437	CDD:234596	93/416 (22%)
		EF_Tu	56..249	CDD:206671	64/251 (25%)
		EFTU_II	257..343	CDD:293898	19/114 (17%)
		mtEFTU_III	347..437	CDD:294005	7/25 (28%)
eef2a.1	NP_001038626.2	PTZ00416	1..854	CDD:240409	93/416 (22%)
		EF2	20..233	CDD:206672	58/217 (27%)
		Translation_Factor_II_like	392..486	CDD:295476	8/35 (23%)
		EF2_snRNP_III	511..572	CDD:293918
		aeEF2_snRNP_like_IV	572..744	CDD:238839
		eEF2_snRNP_like_C	740..819	CDD:239763
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170592493
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930